Body

New general concept for the treatment of cancer

A team of researchers from five Swedish universities, led by Karolinska Institutet and the Science for Life Laboratory, have identified a new way of treating cancer. The concept is presented in the journal Nature and is based on inhibiting a specific enzyme called MTH1, which cancer cells, unlike normal cells, require for survival. Without this enzyme, oxidized nucleotides are incorporated into DNA, resulting in lethal DNA double-strand breaks in cancer cells.

Call for circumcision gets a boost

Rochester, MN, April 2, 2014 – In the United States the rate of circumcision in men has increased to 81% over the past decade. In an important new study just published in advance in Mayo Clinic Proceedings authors from Australia and the United States have shown that the benefits of infant male circumcision to health exceed the risks by over 100 to 1.

Killing a name of an extinct sea cow species

Sirenians, or sea cows, are a particular group of mammals that superficially resembles whales in having, amongst other features, a streamlined-body and horizontal tail fluke. Though belonging to the so-called marine mammals, such as whales and seals, sea cows are members of a group having a single origin that includes their closest living relatives, the proboscideans (or elephants in the broader sense).

One or 2? How to decide how many species you have got

It is often difficult to decide whether two animals belong to the same or two distinct species. This can be especially challenging for animals which externally look very similar.

Don't move a mussel (or a clam, or a snail)

(Millbrook, NY) Anyone that has spent time at a seaside pier has witnessed the destruction barnacles wreak on boat hulls. But biofouling animals are not limited to marine environments. A new paper published in the journal Frontiers in Ecology and the Environment estimates that the global management of freshwater mussels, clams, and other clinging animals costs $277 million U.S. dollars annually.

Beyond proficiency: How early English exposure influences non-native speakers

PRINCETON, N.J.—Non-native speakers exposed to English before moving to America are more likely to use the language in their daily lives in the United States, according to a report led by Princeton University's Woodrow Wilson School of Public and International Affairs.

Radiation able to be securely stored in nontoxic molecule, study finds

MANHATTAN, Kan. — Researchers have discovered that microscopic "bubbles" developed at Kansas State University are safe and effective storage lockers for harmful isotopes that emit ionizing radiation for treating tumors.

The findings can benefit patient health and advance radiation therapy used to treat cancer and other diseases, said John M. Tomich, a professor of biochemistry and molecular biophysics who is affiliated with the university's Johnson Cancer Research Center.

Strain-specific Lyme disease immunity lasts for years, Penn research finds

Lyme disease, if not treated promptly with antibiotics, can become a lingering problem for those infected. But a new study led by researchers from the University of Pennsylvania has some brighter news: Once infected with a particular strain of the disease-causing bacteria, humans appear to develop immunity against that strain that can last six to nine years.

Criticism of violent video games has decreased as technology has improved, gamers age

COLUMBIA, Mo. – Members of the media and others often have attributed violence in video games as a potential cause of social ills, such as increased levels of teen violence and school shootings. Now, a University of Missouri researcher has found that media acceptance of video game violence has increased as video game technology has improved over time. Greg Perreault, a doctoral student at the MU School of Journalism, examined the coverage of violent video games throughout the 1990s by GamePro Magazine, the most popular video game news magazine during that time period.

Researchers identify how zinc regulates a key enzyme involved in cell death

The molecular details of how zinc, an essential trace element of human metabolism, interacts with the enzyme caspase-3, which is central to apoptosis or cell death, have been elucidated in a new study led by researchers at Virginia Commonwealth University. The study is featured on the cover of the April issue of the journal Angewandte Chemie's International Edition.

Pharmocogenomics has not fulfilled its promise to developing countries

From 1997 to 2010, despite promises made by the international scientific community, pharmacogenomic research produced few studies focusing on rare, orphan and tropical diseases prevalent in developing countries. Catherine Olivier, bioethics research at the University of Montreal's School of Public Health, recently published these findings in the journal Global Public Health.

Albertans support perinatal mental health screening

After struggling with anxiety and depression since her teens, Lana Berry hit bottom at age 26. Divorced, unemployed and back living with her parents, she found herself in a dark place—"as sick as I'd ever been."

Berry persevered, pouring her energy into getting better. She found work, met the love of her life, remarried and, six years after her low point, found out she was going to be a mom. Given her past, she was understandably anxious about what to expect.

Making the most of carbon nanotube-liquid crystal combos

Dispersions of carbon nanotubes with liquid crystals have attracted much interest because they pave the way for creating new materials with added functionalities. Now, a study published in EPJ E by Marina Yakemseva and colleagues at the Nanomaterials Research Institute in Ivanovo, Russia, focuses on the influence of temperature and nanotube concentration on the physical properties of such combined materials.

Why were young males behind recent attacks on schools and public gatherings?

New Rochelle, NY, April 2, 2014–Recent mass killings at schools, movie theaters, political rallies, and races, whether in the U.S., Norway, or elsewhere around the globe, have generally been perpetrated by young males 15-30 years of age. In a provocative Roundtable Discussion published in the preview issue of Violence and Gender, a new peer-reviewed journal from Mary Ann Liebert, Inc., publishers, a multidisciplinary expert panel explores the possible reasons for high incidence of these crimes, especially in the U.S., and the motives of the young male perpetrators.

Pathological complete response predictor of favorable breast cancer outcome

Results of EORTC trial 10994 appearing in the Annals of Oncology show that pathological complete response after neoadjuvant chemotherapy is an independent predictive factor of favorable clinical outcomes in all molecular subtypes of breast cancer.