Body

Protein found in insect blood that helps power pests' immune responses

MANHATTAN, Kansas — Pest insects may be sickened to learn to that researchers at Kansas State University have discovered a genetic mechanism that helps compromise their immune system.

Michael Kanost, university distinguished professor of biochemistry and molecular biophysics, led a study by Kansas State University researchers that looked at how protein molecules in the blood of insects function in insects' immune system. Insects use proteins that bind to the surface of pathogens to detect infections in their body.

The Costco effect: Do consumers buy less variety at bigger stores?

Do consumers make the same choices when products such as beer, soft drinks, or candy bars are sold individually or in bundles? According to a new study in the Journal of Consumer Research, consumers purchase a greater variety of products when they are packaged individually rather than bundled together.

Defective gene renders diarrhoea vaccine ineffective

Every year rotavirus causes half a million diarrhoea-related deaths amongst children in developing countries. Existing vaccines provide poor protection. The reason could be a widespread genetic resistance amongst children, according to virologists at Linköping University.

Scientists link ALS progression to increased protein instability

LA JOLLA, CA—October 13, 2014—A new study by scientists from The Scripps Research Institute (TSRI), Lawrence Berkeley National Laboratory (Berkeley Lab) and other institutions suggests a cause of amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease.

"Our work supports a common theme whereby loss of protein stability leads to disease," said John A. Tainer, professor of structural biology at TSRI and senior scientist at Berkeley Lab, who shared senior authorship of the new research with TSRI Professor Elizabeth Getzoff.

Mediterranean diet, olive oil and nuts can help reverse metabolic syndrome

For people with metabolic syndrome, a Mediterranean diet supplemented with extra-virgin olive oil or nuts may help reverse the condition, indicate findings from a clinical trial published in CMAJ (Canadian Medical Association Journal).

About 25% of adults around the world have metabolic syndrome. The syndrome exists in the presence of three or more factors such as large waist circumference, high blood pressure, low HDL-cholesterol, high levels of triglycerides and high blood sugar concentrations that can increase the risk of diabetes, heart disease and death.

For one family, zebrafish help provide genetic answers

Research in zebrafish has helped identify the cause of an unknown genetic disorder affecting a boy and two of his uncles, scientists report in an article published October 14 in the journal Genetics.

The findings demonstrate the growing importance of zebrafish as laboratory models of rare diseases. Such models allow geneticists to make sense of the deluge of candidate disease genes being uncovered by advances in sequencing technologies. Although rare diseases are uncommon individually, together they affect as many as 25 million people in the United States.

Side effects of cancer prevention surgery can be helped with education program

BOSTON –– More women are having ovary-removing surgery as a cancer prevention measure, but many are often unaware of sexual or psychological side effects of the procedure. A new study by researchers at Dana-Farber Cancer Institute shows a half-day educational program can help successfully deal with these issues by educating women on how to address them.

Scientists create new protein-based material with some nerve

Berkeley — Scientists at the University of California, Berkeley, have taken proteins from nerve cells and used them to create a "smart" material that is extremely sensitive to its environment. This marriage of materials science and biology could give birth to a flexible, sensitive coating that is easy and cheap to manufacture in large quantities.

Feeling guilty or ashamed? Think about your emotions before you shop

Suppose you grabbed a few cookies before heading out to the grocery store and start to feel guilty or ashamed about breaking your diet. According to a new study in the Journal of Consumer Research, feeling guilty might find you comparing calories in different cartons of ice cream. Feeling ashamed might keep you from buying any ice cream in the first place.

Marketing an innovative new product? An exciting product launch could hurt sales

Should every successful product launch involve some sort of dazzling spectacle? A new study in the Journal of Consumer Research tells us that this might be a great way to market an upgrade, but a flashy launch could backfire if a new product is truly innovative.

Discovery of cellular snooze button advances cancer and biofuel research

EAST LANSING, Mich. – The discovery of a cellular snooze button has allowed a team of Michigan State University scientists to potentially improve biofuel production and offer insight on the early stages of cancer.

The discovery that the protein CHT7 is a likely repressor of cellular quiescence, or resting state, is published in the current issue of the Proceedings of the National Academy of Sciences. This cellular switch, which influences algae's growth and oil production, also wields control of cellular growth – and tumor growth – in humans.

Sustained feedback to doctors may help maintain appropriate antibiotic usage in children

A program that provides guidance to primary care physicians about appropriately prescribing antibiotics for children is effective, but its improvements wear off after regular auditing and feedback are discontinued.

"Our findings suggest that interventions with outpatient healthcare providers should include continued feedback to clinicians to remain effective," said study leader Jeffrey S. Gerber, M.D., Ph.D., an infectious diseases specialist at The Children's Hospital of Philadelphia (CHOP).

'Grapes of Wrath': Stomping out grape disease one vineyard at a time

Cracking the genetic code of a common disease affecting grape production could improve vineyard management and help protect the multibillion-dollar industry that includes raisins, juice, jam/jelly, fresh grapes, grape-seed extract and oil, vinegar and wine.

Brand loyalty: What happens when our favorite products are unavailable?

What would happen to all those millions of Snickers fans if their favorite chocolate bar was temporarily out of stock? Would they wait for it to be available again or would they quickly switch allegiance to Milky Way or Kit Kat? According to a new study in the Journal of Consumer Research, when you can't get your favorite product, you'll quickly forget about it if you can find a good replacement.

New treatment target identified for aggressive breast cancer

AUGUSTA, Ga. – One of the first-known oncogenes has a protein partner that helps breast cancer proliferate and when it's blocked, so is the cancer, scientists report.

The gene ErbB2, commonly called HER2, is highly expressed in about 25 percent of breast cancers. Scientists have now found the protein Erbin, thought to be an anti-tumor factor, also is highly expressed in these cancers and essential to ErbB2's support of breast cancer.