Body

Discovery of heart's repair process suggests new treatment strategy for heart attack

UCLA researchers have discovered that some scar-forming cells in the heart, known as fibroblasts, have the ability to become endothelial cells — the cells that form blood vessels. The finding could point the way toward a new strategy for treating people who have suffered a heart attack, because increasing the number of blood vessels in the heart boosts its ability to heal after injury.

In studies involving mice, the UCLA team also found that a drug could enhance this phenomenon and improve the repair process after a heart attack.

UNC researchers boost the heart's natural ability to recover after heart attack

CHAPEL HILL – Researchers from the UNC School of Medicine have discovered that cells called fibroblasts, which normally give rise to scar tissue after a heart attack, can be turned into endothelial cells, which generate blood vessels to supply oxygen and nutrients to the injured regions of the heart, thus greatly reducing the damage done following heart attack.

Post-tonsillectomy complications more likely in kids from lower-income families

Removing a child's tonsils is one of the most common surgeries performed in the United States, with approximately 500,000 children undergoing the procedure each year. New research finds that children from lower-income families are more likely to have complications following the surgery.

In the first study of its kind to analyze post-operative complications requiring a doctor's visit within the first 14 days after tonsillectomy, researchers saw a significant disparity based on income status, race and ethnicity.

Tuning light to kill deep cancer tumors

WORCESTER, MA – An international group of scientists led by Gang Han, PhD, at the University of Massachusetts Medical School, has combined a new type of nanoparticle with an FDA-approved photodynamic therapy to effectively kill deep-set cancer cells in vivo with minimal damage to surrounding tissue and fewer side effects than chemotherapy. This promising new treatment strategy could expand the current use of photodynamic therapies to access deep-set cancer tumors.

New guideline in genetic testing for certain types of muscular dystrophy

Rochester, Minn. – The American Academy of Neurology (AAN) and the American Association of Neuromuscular & Electrodiagnostic Medicine (AANEM) offer a new guideline on how to determine what genetic tests may best diagnose a person's subtype of limb-girdle or distal muscular dystrophy. The guideline is published in the October 14, 2014, print issue of Neurology®, the medical journal of the AAN.

Key moment mapped in assembly of DNA-splitting molecular machine

UPTON, NY—The proteins that drive DNA replication—the force behind cellular growth and reproduction—are some of the most complex machines on Earth. The multistep replication process involves hundreds of atomic-scale moving parts that rapidly interact and transform. Mapping that dense molecular machinery is one of the most promising and challenging frontiers in medicine and biology.

Bullies in the workplace

AMES, Iowa – The stories are shocking and heartbreaking, but they are often disjointed and hard to follow. In severe cases, the narratives are even more chaotic. This is reality for victims of workplace bullying and a major reason why they stay silent, said Stacy Tye-Williams, an assistant professor of communications studies and English at Iowa State University.

Study models ways to cut Mexico's HIV rates

PROVIDENCE, R.I. [Brown University] — To address the HIV epidemic in Mexico is to address it among men who have sex with men (MSM), because they account for a large percentage of the country's new infections, says Omar Galárraga, assistant professor of health services policy and practice in the Brown University School of Public Health.

Sharks that hide in coral reefs may be safe from acidifying oceans

A study published online today in the journal Conservation Physiology has shown that the epaulette shark (Hemiscyllium ocellatum) displays physiological tolerance to elevated carbon dioxide (CO2) in its environment after being exposed to CO2 levels equivalent to those that are predicted for their natural habitats in the near future.

This image shows an epaulette shark in the wild.

(Photo Credit: M. Heupel)

Sheltering habits help sharks cope with acid oceans

A shark's habitat can reduce its sensitivity to rising CO2 levels, according to Australian scientists.

Globally, ocean acidification - linked to emissions of greenhouse gases - remains a major concern and scientists say it will harm many marine species over the next century.

Subsidies help breast cancer patients adhere to hormone therapy

A federal prescription-subsidy program for low-income women on Medicare significantly improved their adherence to hormone therapy to prevent the recurrence of breast cancer after surgery.

Dolphin 'breathalyzer' could help diagnose animal and ocean health

Alcohol consumption isn't the only thing a breath analysis can reveal. Scientists have been studying its possible use for diagnosing a wide range of conditions in humans — and now in the beloved bottlenose dolphin. In a report in the ACS journal Analytical Chemistry, one team describes a new instrument that can analyze the metabolites in breath from dolphins, which have been dying in alarming numbers along the Atlantic coast this year.

Discarded cigarette ashes could go to good use -- removing arsenic from water

Arsenic, a well-known poison, can be taken out of drinking water using sophisticated treatment methods. But in places that lack the equipment or technical know-how required to remove it, it still laces drinking water and makes people sick. To tackle this problem, scientists have come up with a new low-cost, simple way to remove arsenic using leftovers from another known health threat — cigarettes. They report their method in ACS' journal Industrial & Engineering Chemistry Research.

Academies call for consequences from the Ebola virus epidemic

The Ebola virus is spreading rapidly and to an unexpected extent. The outbreak does not follow the patterns experienced in the past and the virus shows a new disease dynamic in regions, where it has never been recorded before. For this reason, the German National Academy of Sciences Leopoldina, acatech – the German Academy of Science and Engineering, and the Union of the German Academies of Sciences and Humanities have presented a statement on the Ebola epidemic today.

Researchers look to exploit females' natural resistance to infection

Researchers have linked increased resistance to bacterial pneumonia in female mice to an enzyme activated by the female sex hormone estrogen.

Females are naturally more resistant to respiratory infections than males. Now, an international team of scientists has shown that increased resistance to bacterial pneumonia in female mice is linked to the enzyme nitric oxide synthase 3 (NOS3). They also show that this enzyme is ultimately activated by the release of the female sex hormone estrogen.