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Rare bacteria outbreak in cancer clinic tied to lapse in infection control procedure

CHICAGO (February 12, 2014) – Improper handling of intravenous saline at a West Virginia outpatient oncology clinic was linked with the first reported outbreak of Tsukamurella spp., gram-positive bacteria that rarely cause disease in humans, in a new report from the Centers for Disease Control and Prevention (CDC). The report was published in the March issue of Infection Control and Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America.

Solving an evolutionary puzzle

For four decades, waste from nearby manufacturing plants flowed into the waters of New Bedford Harbor—an 18,000-acre estuary and busy seaport. The harbor, which is contaminated with polychlorinated biphenyls (PCBs) and heavy metals, is one of the EPA's largest Superfund cleanup sites.

It's also the site of an evolutionary puzzle that researchers at Woods Hole Oceanographic Institution (WHOI) and their colleagues have been working to solve.

Revision to rules for color in dinosaurs suggests connection between color and physiology

New research that revises the rules allowing scientists to decipher color in dinosaurs may also provide a tool for understanding the evolutionary emergence of flight and changes in dinosaur physiology prior to its origin.

Cancer researchers discover pre-leukemic stem cell at root of AML, relapse

(TORONTO, Canada – Feb. 12, 2014) – Cancer researchers led by stem cell scientist Dr. John Dick have discovered a pre-leukemic stem cell that may be the first step in initiating disease and also the culprit that evades therapy and triggers relapse in patients with acute myeloid leukemia (AML).

Advanced techniques yield new insights into ribosome self-assembly

CHAMPAIGN, Ill. — Ribosomes, the cellular machines that build proteins, are themselves made up of dozens of proteins and a few looping strands of RNA. A new study, reported in the journal Nature, offers new clues about how the ribosome, the master assembler of proteins, also assembles itself.

America's only Clovis skeleton had its genome mapped

They lived in America about 13,000 years ago where they hunted mammoth, mastodons and giant bison with big spears. The Clovis people were not the first humans in America, but they represent the first humans with a wide expansion on the North American continent – until the culture mysteriously disappeared only a few hundred years after its origin. Who the Clovis people were and which present day humans they are related to has been discussed intensely and the issue has a key role in the discussion about how the Americas were peopled.

Cities support more native biodiversity than previously thought

(Santa Barbara, Calif.) — The rapid conversion of natural lands to cement-dominated urban centers is causing great losses in biodiversity. Yet, according to a new study involving 147 cities worldwide, surprisingly high numbers of plant and animal species persist and even flourish in urban environments — to the tune of hundreds of bird species and thousands of plant species in a single city.

Help for a scarred heart: Scarring cells turned to beating muscle

ANN ARBOR – Poets and physicians know that a scarred heart cannot beat the way it used to, but the science of reprogramming cells offers hope--for the physical heart, at least.

A team of University of Michigan biomedical engineers has turned cells common in scar tissue into colonies of beating heart cells. Their findings could advance the path toward regenerating tissue that's been damaged in a heart attack.

New NIST method evaluates response to oxidation in live cells

Researchers at the National Institute of Standards and Technology (NIST) have developed a new method for accurately measuring a key process governing a wide variety of cellular functions that may become the basis for a "health checkup" for living cells.

Popular disinfectants do not kill HPV

Commonly used disinfectants do not kill human papillomavirus (HPV) that makes possible non-sexual transmission of the virus, thus creating a need for hospital policy changes, according to researchers from Penn State College of Medicine and Brigham Young University.

"Because it is difficult to produce infectious HPV particles for research, little has been known about HPV susceptibility to disinfection," said Craig Meyers, Distinguished Professor of Microbiology and Immunology, Penn State College of Medicine.

Test for persistent Lyme infection using live ticks shown safe in clinical study

In a first-of-its-kind study for Lyme disease, researchers have used live, disease-free ticks to see if Lyme disease bacteria can be detected in people who continue to experience symptoms such as fatigue or arthritis after completing antibiotic therapy. The technique, called xenodiagnosis, attempts to find evidence of a disease-causing microbe indirectly, through use of the natural disease-carrier—in this case, ticks.

U-M scientists & colleagues investigate the fiber of our being

ANN ARBOR, Mich. — We are all aware of the health benefits of dietary fiber. But what is dietary fiber and how do we metabolize it?

Research at the University of Michigan Medical School, the University of York's Structural Biology Laboratory, and institutions in Canada and Sweden, has begun to uncover how our gut bacteria metabolize the complex dietary carbohydrates found in fruits and vegetables.

Study highlights long-term effects of childhood obesity on late-life health

Childhood obesity rates have nearly tripled in the previous 30 years and researchers are asking the important question of how this epidemic will impact the future health of these obese children and public health in general. A University of Colorado Cancer Center article recently published in the journal Gerontology shows that even in cases in which obese children later lose weight, the health effects of childhood obesity may be long-lasting and profound.

Study: IOC should ban lead shot to help wildlife, water

With the world watching the Sochi Winter Olympics including the biathlon shooting events, now is the time for the International Olympic Committee (IOC) to ban the use of lead shot to prevent wildlife poisoning and health threats to surface and groundwater, says a new paper co-authored this month by a University of Guelph biologist.

Thousands of tons of lead shot discharged every year during training by Olympic shooters pose a threat to birds and mammals and to water resources, says Vernon Thomas, professor emeritus in the Department of Integrative Biology.

From artificial to natural, the food industry makes a major shift

Extracts from algae, rosemary and monk fruit could soon replace synthetic ingredients and food additives such as Blue No. 1, BHT and aspartame that label-conscious grocery shoppers are increasingly shunning. Research is enabling this shift from artificial colors, sweeteners and preservatives to naturally derived ones, and could soon yield many more natural options, reports Chemical & Engineering News, the weekly newsmagazine of the American Chemical Society.