Body

HOUSTON – Consider two drivers, each with a key that fits the same car. Driver 1 wants simply to turn on the ignition and leave the vehicle idling, ready and waiting to roll. Driver 2 wants to take it on a destructive joy ride.

Such is the case with two proteins identified by scientists at The University of Texas MD Anderson Cancer Center that fit on to the same binding site on an important cellular growth factor receptor called FGFR2 with starkly different results.

In 2010, the total cost of cancer care in the United States reached $125 billion. Globally, the economic toll from cancer is nearly 20 percent higher than the leading cause of death, heart disease. Cancer patients are also living longer today, which is further increasing the cost of their continued care. As the health insurance exchanges have opened and heated debate about the Affordable Care Act (ACA) continues, many questions remain, including the $125 billion question: "How will the ACA affect the most expensive disease: cancer?"

New Rochelle, January 23, 2014—The search for extraterrestrial life extends far beyond Earth's solar system, looking for planets or moons outside the "stellar habitable zone" that may have environments even more favorable to supporting life than here on Earth.

WASHINGTON, Jan. 23—In work that has major implications for improving the performance of building insulation, scientists at the University of Namur in Belgium and the University of Hassan I in Morocco have calculated that hairs that reflect infrared light may contribute significant insulating power to the exceptionally warm winter coats of polar bears and other animals. The research was published today in The Optical Society's (OSA) open-access journal, Optics Express.

New Rochelle, NY, January 23, 2013-The U.S. Food and Drug Administration (FDA) mandates adequate enrollment of women in post-approval studies (PAS) of medical devices to ensure that any sex differences in device safety and effectiveness are not overlooked. A group of authors from the FDA report the results of a study evaluating the participation of women and analysis of sex differences in PAS in Journal of Women's Health, a peer-reviewed publication from Mary Ann Liebert, Inc., publishers.

A visit to the Natural History Museum, London, yielded an unexpected surprise for Dr. Joseph Parker, a UK biologist based in New York at Columbia University and the American Museum of Natural History.

The ribosome can be thought of as a decryption device housed within the cell. It is able to decipher the genetic code, which is delivered in the form of messenger ribonucleic acid (mRNA), and translate it into a specific sequence of amino acids. The final assembly of amino acids into long protein chains also takes place in these enzyme complexes. Without ribosomes, a cell would be unable to produce any proteins. Due to their central function, these enzyme complexes have long been the focus of attention of biologists.

This news release is available in German.

Each cell in our body is unique. Even cells of the same tissue type that look identical under the microscope differ slightly from each other. To understand how a heart cell can develop from a stem cell, why one beta-cell produces insulin and the other does not, or why a normal tissue cell suddenly mutates to a cancer cell, scientists have been targeting the activities of ribonucleic acid, RNA.

Singapore, 23 January 2014 – A team of scientists from the National Cancer Centre Singapore (NCCS), the Institut de Génétique et de Biologie Moleculaire et Cellulaire (Strassbourg France), and the Institut Albert Bonniot (Grenoble, France) have made an important finding on how genes are regulated. This study will be released in the January 30th, 2014 print issue of the journal Nature.

Swedish archaeologists in Jordan led by Professor Peter M. Fischer from the University of Gothenburg have excavated a nearly 60-metre long well-preserved building from 1100 B.C. in the ancient settlement Tell Abu al-Kharaz. The building is from an era characterised by major migration.

New finds support the theory that groups of the so-called Sea Peoples emigrated to Tell Abu al-Kharaz. They derive from Southern or Eastern Europe and settled in the Eastern Mediterranean region all the way to the Jordan Valley.

The findings of the scientists of the Institute of Diabetes and Regeneration Research (IDR) at Helmholtz Zentrum München (HMGU) provide new insights into the molecular regulation of stem cell differentiation. These results reveal important target structures for regenerative therapy approaches to chronic diseases such as diabetes.

To test whether female mate choice enhances the health and disease-resistance of offspring, either through immune resistance, tolerance to infection, or both, researchers led by Dustin Penn tested female house mice's preferences (Mus musculus) for particular males and then experimentally assigned each female to mate with either their preferred or their non-preferred male.

NEW YORK (January 22, 2014) -- Use of a twice-daily pill could turn a deadly blood cancer into a highly treatable disease, according to scientists at Weill Cornell Medical College who led a multinational research team. Their findings on the therapy for chronic lymphocytic leukemia (CLL), reported in the Jan. 22 issue of the New England Journal of Medicine, suggest that patients may be able to avoid having to take debilitating chemotherapy.

Silicon-based electronics has certain limits, in the physical sense of the word: this type of circuit can never become "nano" because of the physical laws governing the flow of electrons. This imposes a halt to the process of miniaturization of electronic devices. One of the possible solutions is to use molecules as circuits, but their poor conduction capabilities make them unlikely candidates.

NEW YORK, NY (January 22, 2014) — Columbia University Medical Center (CUMC) researchers have identified a gene, called matrix metalloproteinase-9 (MMP-9), that appears to play a major role in motor neuron degeneration in amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease. The findings, made in mice, explain why most but not all motor neurons are affected by the disease and identify a potential therapeutic target for this still-incurable neurodegenerative disease. The study was published today in the online edition of the journal Neuron.