Body

Smoking affects allergy-relevant stem cells

Leipzig. Environmental contaminants, such as smoking, are harmful to the human organism in relation to the occurrence of allergies. This is known. Until now, researchers had never investigated whether and to what extent environmental contaminants also affect allergy-relevant stem cells. For the first time a team at the Helmholtz Centre for Environmental Research (UFZ) has found evidence for this: Smoking affects the development of peripheral allergy-relevant stem cells in the blood. In order to present this result Dr. Irina Lehmann and Dr.

'Missing link' discovered in the defence mechanism of the tuberculosis pathogen

Brussels, 14 November 2012 – Flemish biologists lead by Joris Messens (VIB / Vrije Universiteit Brussel) have discovered that Mycobacterium tuberculosis – the bacterium that causes tuberculosis – has an ingenious defence mechanism against oxygen. This knowledge is important in the search for a treatment for tuberculosis. 9.4 million people are infected with tuberculosis annually and 1.7 million people die as a result.

The leggiest animal on Earth lives in the outskirts of Silicon Valley

The most noticeable thing about millipedes are their number of legs, which lined up along their bodysides step in synchronous "metachronal waves". The acme of legginess in millipedes, and all animals for that matter, is the Californian species Illacme plenipes (literally meaning "in highest fulfillment of feet"). The females have up to an astounding 750 legs, outclassing the males who only have a maximum leg count of 562.

Pancreas stem cell discovery may lead to new diabetes treatments

Stem cells in the adult pancreas have been identified that can be turned into insulin producing cells, a finding that means people with type 1 diabetes might one day be able to regenerate their own insulin-producing cells.

The discovery was made by scientists from the Walter and Eliza Hall Institute and provides further evidence that stem cells don't only occur in the embryo.

PCBs, other pollutants may play role in pregnancy delay

Couples with high levels of PCBs and similar environmental pollutants take longer to achieve pregnancy in comparison to other couples with lower levels of the pollutants, according to a preliminary study by researchers at the National Institutes of Health and other institutions.

Timing of first menstrual cycle may be predictor of cardiovascular disease risk in women

Chevy Chase, MD—Age at onset of menarche (first menstrual cycle) is associated with increased body mass index (BMI), waist circumference, and overall obesity in adulthood, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).

BPA shown to disrupt thyroid function in pregnant animals and offspring

Chevy Chase, MD –– In utero exposure to bisphenol A (BPA) can be associated with decreased thyroid function in newborn sheep, according to a recent study accepted for publication in Endocrinology, a journal of The Endocrine Society. Hypothyroidism is characterized by poor mental and physical performance in human adults and in children can result in cognitive impairment and failure to grow normally.

Metals versus microbes: The biocidal effect of metalloacid-coated surfaces

A new study published in BioMed Central's open access journal Antimicrobial Resistance and Infection Control reports of a phenomenon that could help control the spread of hospital-acquired infections: a surface-coating of metalloacids kills off microbial strains, even in multidrug-resistant microorganisms.

Cancer: Exercise reduces tiredness

Aerobic exercise can help relieve the fatigue often associated with cancer and cancer treatment, according to Cochrane researchers. Their updated systematic review strengthens findings from an earlier version on cancer-related fatigue published in The Cochrane Library.

Fatigue is a common and potentially long-lasting side-effect of cancer and cancer treatment. It may last for months or years. Dealing with cancer-related fatigue is crucial because those who suffer its effects may be less inclined to continue with treatment.

Mobile phone services help smokers quit

Support for quitting smoking via text and video messages can help smokers kick the habit according to a new Cochrane systematic review. The authors of the review found that people were more likely to stay away from cigarettes over a six month period if they received motivational messages and advice to their mobile phones.

Grasshoppers change their tune to stay tuned over traffic noise

Grasshoppers are having to change their song – one of the iconic sounds of summer – to make themselves heard above the din of road traffic, ecologists have discovered. The study, published in the British Ecological Society's journal Functional Ecology, is the first to show that man-made noise affects natural insect populations.

Bacterial DNA sequence used to map an infection outbreak

For the first time, researchers have used DNA sequencing to help bring an infectious disease outbreak in a hospital to a close.

Drug shrinks brain tumors in children with tuberous sclerosis complex

A drug originally developed to prevent the rejection of transplanted organs has now been shown to dramatically reduce a particular kind of brain tumor in patients with tuberous sclerosis complex (TSC) -- a genetic disease that causes tumors to grow on vital organs.

The study, published online in The Lancet, is the latest to show the effectiveness of everolimus in slowing the cell growth that is overactive in patients with TSC.

International action needed to ensure the quality of medicines and tackle the fake drugs trade

Their call comes just days before 100 World Health Organisation member states hold their first meeting to discuss the problem, and the authors hope it will help to influence the debate and lead to some concrete actions.

Common enzyme deficiency may hinder plans to eradicate malaria

In malaria-endemic countries, 350 million people are predicted to be deficient in an enzyme that means they can suffer severe complications from taking primaquine, a key drug for treating relapsing malaria, according to a study funded by the Wellcome Trust and published in this week's PLOS Medicine.