Researchers from Nottingham have played their part in the discovery of a rare genetic mutation that increases the risk of Alzheimer's disease, in a study with major implications for understanding the causes of the disease.
The international team, which involved a research team led by Kevin Morgan, Professor of Human Genomics and Molecular Genetics at The University of Nottingham, used data from more than 25,000 people to link a rare variant of the TREM2 gene — which is known to play a role in the immune system — to a higher risk of Alzheimer's.