Body

New findings on glucagon synthesis

Researchers at Karolinska Institutet in Sweden have shown that the cells that produce glucagon are stimulated by the hormone itself. A previous study by the same group demonstrated that this principle also applies to insulin. This means that a feedback system is at work in the body, whereby hormone secreting cells receive an immediate signal to produce more of the hormone.

Biophysicists unravel cellular 'traffic jams' in active transport

AMHERST, Mass. – Inside many growing cells, an active transport system runs on nano-sized microtubule tracks that resemble a highway, complete with motors carrying cargo quickly from a central supply depot to growing tips or wherever materials are needed. In spite of the cell's busy, high-traffic environment, researchers know the system somehow works efficiently, without accidents or traffic jams.

Plant organ development breakthrough

Stanford, CA — Plants grow upward from a tip of undifferentiated tissue called the shoot apical meristem. As the tip extends, stem cells at the center of the meristem divide and increase in numbers. But the cells on the periphery differentiate to form plant organs, such as leaves and flowers. In between these two layers, a group of boundary cells go into a quiescent state and form a barrier that not only separates stem cells from differentiating cells, but eventually forms the borders that separate the plant's organs.

New study shows probiotics help fish grow up faster and healthier

BALTIMORE, MD (December 3, 2012)— Probiotics like those found in yogurt are not only good for people--they are also good for fish. A new study by scientists at the Institute of Marine and Environmental Technology found that feeding probiotics to baby zebrafish accelerated their development and increased their chances of survival into adulthood.

Western University researchers make breakthrough in arthritis research

Researchers at Western University have made a breakthrough that could lead to a better understanding of a common form of arthritis that, until now, has eluded scientists.

New Jamaica butterfly species emphasizes need for biodiversity research

GAINESVILLE, Fla. — University of Florida scientists have co-authored a study describing a new Lepidoptera species found in Jamaica's last remaining wilderness.

Baby's health is tied to mother's value for family

The value that an expectant mother places on family—regardless of the reality of her own family situation—predicts the birthweight of her baby and whether the child will develop asthma symptoms three years later, according to new research from USC.

The findings suggest that one's culture is a resource that can provide tangible physical health benefits.

Children with autism arrive at emergency room for psychiatric crisis 9 times more than peers

BALTIMORE, Md. (December 3, 2012) – In the first study to compare mental health-related emergency department (ED) visits between children with and without autism spectrum disorders (ASD), researchers found that ED visits are nine times more likely to be for psychiatric reasons if a child has an ASD diagnosis. Published in the journal Pediatric Emergency Care (Epub ahead of print), the study found externalizing symptoms, such as severe behaviors tied to aggression, were the leading cause of ED visits among children with ASD.

DNA analysis of microbes in a fracking site yields surprises

SAN FRANCISCO—Researchers have made a genetic analysis of the microbes living deep inside a deposit of Marcellus Shale at a hydraulic fracturing, or "fracking," site, and uncovered some surprises.

They expected to find many tough microbes suited to extreme environments, such as those that derive from archaea, a domain of single-celled species sometimes found in high-salt environments, volcanoes, or hot springs. Instead, they found very few genetic biomarkers for archaea, and many more for species that derive from bacteria.

Multitasking plasmonic nanobubbles kill some cells, modify others

HOUSTON – (Dec. 3, 2012) – Researchers at Rice University have found a way to kill some diseased cells and treat others in the same sample at the same time. The process activated by a pulse of laser light leaves neighboring healthy cells untouched.

The unique use for tunable plasmonic nanobubbles developed in the Rice lab of Dmitri Lapotko shows promise to replace several difficult processes now used to treat cancer patients, among others, with a fast, simple, multifunctional procedure.

U-M study shows BPA exposure in fetal livers

ANN ARBOR—New research from the University of Michigan School of Public Health found BPA, or bisphenol A, in fetal liver tissue, demonstrating that there is considerable exposure to the chemical during pregnancy.

Researchers also found a proportionately higher concentration of free BPA—as opposed to the conjugated forms modified by the body for elimination—further showing that in fetuses the ability to eliminate the chemical from the body is not the same as in adults.

Kansas State University research shows iron's importance in infection, suggests new therapies

MANHATTAN, KAN. -- A Kansas State University research team has resolved a 40-year-old debate on the role of iron acquisition in bacterial invasion of animal tissues.

The collaborative research -- led by Phillip Klebba, professor and head of the department of biochemistry -- clarifies how microorganisms colonize animal hosts and how scientists may block them from doing so. The findings suggest new approaches against bacterial disease and new strategies for antibiotic development.

College students report low flu vaccine rate

WINSTON-SALEM, N.C. – Dec. 3, 2012 – College football and basketball games may provide more than a way for students to show school spirit – they could help prevent the flu.

According to a new study by researchers at Wake Forest Baptist Medical Center, colleges and universities should implement new or improved influenza vaccine strategies, such as giving flu shots at sporting events or during campus-wide, day-long campaigns, to increase the number of their students who get the annual flu vaccine.

PAR1 contributes to influenza A virus pathogenicity in mice

Infection with the influenza virus induces an immune response to fight the virus; however, this natural defense sometimes results in excessive inflammation that can damage the lungs.

In the Journal of Clinical Investigation, researchers led by Béatrice Riteau at the University of Lyon in Lyon, France, found that mice infected with influenza A had increased PAR1 activity, a protein that attracts inflammatory cells to the site of infection.

Stem cell-derived dopaminergic neurons rescue motor defects in Parkinsonian monkeys

Parkinson's disease is a degenerative disorder of the central nervous system that is characterized by tremors, rigidity, slowness of movement, and difficulty walking. It is caused by loss of the neurons that produce the neurotransmitter dopamine (known as dopaminergic neurons). One of the primary goals in Parkinson's disease research is to develop a replacement for dopaminergic neurons.