Body

Nature Materials study: Boosting heat transfer with nanoglue

Troy, N.Y. – A team of interdisciplinary researchers at Rensselaer Polytechnic Institute has developed a new method for significantly increasing the heat transfer rate across two different materials. Results of the team's study, published in the journal Nature Materials, could enable new advances in cooling computer chips and lighting-emitting diode (LED) devices, collecting solar power, harvesting waste heat, and other applications.

Fish oil helps heal bed sores of the critically ill

Chock-full of Omega-3 fatty acids and antioxidants, fish oil can help lower blood pressure, reduce inflammation in the skin and joints, and promote healthy fetal development. Now a Tel Aviv University researcher has found that it has a positive effect on bedsores, too.

New method for creating long-lived stem cells used for bone replacement

New Rochelle, NY, December 4, 2012—Human mesenchymal stem cells (hMSCs) can develop into bone cells and are useful for tissue engineering and regeneration. However, when grown in the laboratory they quickly lose their ability to continue dividing and they die. A method for genetically engineering hMSCs so they become immortal and still retain their ability to become bone cells is described in an article published in BioResearch Open Access, a bimonthly peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

Super-resolution microscope shows how human T-cells make life or death decisions

Sydney, Australia - Using a super-resolution fluorescent microscope, Australian medical scientists are a step closer to understanding why and how human immune cells decide to activate or not, thus enabling or preventing disease taking hold in the body.

Professor Katharina Gaus and her team at the Centre for Vascular Research based at UNSW's Lowy Cancer Research Centre used some of the most advanced super-resolution optical microscope technology available anywhere in the world to see changes in individual proteins in T-cells – the workhorse of our immune system.

The dance of quantum tornadoes

Tornado-like vortexes can be produced in bizarre fluids which are controlled by quantum mechanics, completely unlike normal liquids. New research published today in the journal Nature Communications demonstrates how massed ranks of these quantum twisters line up in rows, and paves the way for engineering quantum circuits and chips measuring motion ultra-precisely.

New study shows how copper restricts the spread of global antibiotic-resistant infections

New research from the University of Southampton has shown that copper can prevent horizontal transmission of genes, which has contributed to the increasing number of antibiotic-resistant infections worldwide.

Horizontal gene transfer (HGT) in bacteria is largely responsible for the development of antibiotic-resistance, which has led to an increasing number of difficult-to-treat healthcare-associated infections (HCAIs).

Metabolic biomarkers for preventive molecular medicine

One of the big challenges of biomedicine is understanding the origin of illnesses in order to improve early detection and significantly increase recovery rates, as well as being able to do what CNIO researchers call preventive molecular medicine, which consists of identifying those individuals who have a greater molecular risk of suffering certain pathologies in order to prevent them. The ageing of the organism, and therefore of the cells and tissues it is made of, represents the greatest risk factor for the majority of developed-world illnesses, including cancer.

African savannah -- and its lions -- declining at alarming rates

DURHAM, NC -- About 75 percent of Africa's savannahs and more than two-thirds of the lion population once estimated to live there have disappeared in the last 50 years, according to a study published this week in the journal Biodiversity and Conservation.

The study, led by Duke University researchers, estimates the number of lions now living on the savannahs to be as low as 32,000, down from nearly 100,000 in 1960. Lion populations in West Africa have experienced the greatest declines.

Fox invasion threatens wave of extinction, UC research finds

Using DNA detection techniques developed at the University, the team mapped the presence of foxes in Tasmania, predicted their spread and developed a model of their likely distribution as a blueprint for fox eradication, but swift and decisive action is needed.

University of Canberra professor in wildlife genetics and leader of the team, Stephen Sarre, found foxes are widespread in northern and eastern Tasmania and the model developed by his team forecasts they will spread even further with likely devastating consequences for the island's wildlife.

Ray of hope for human Usher syndrome patients

After years of basic research, scientists at Johannes Gutenberg University Mainz (JGU) are increasingly able to understand the mechanisms underlying the human Usher syndrome and are coming ever closer to finding a successful treatment approach. The scientists in the Usher research group of Professor Dr. Uwe Wolfrum are evaluating two different strategies. These involve either the repair of mutated genes or the deactivation of the genetic defects using agents. Based on results obtained to date, both options seem promising.

Fitness for toad sperm: The secret is to mate frequently

Fertility tests frequently reveal that males have problems with the quality of their sperm. The problems often relate to sperm senescence, which is a reduction in quality with age. Sperm senescence can arise either before or after the DNA in the sperm cells is produced by a process known as meiosis. So-called "pre-meiotic" senescence results from accumulated damage in the germline cells with increasing age and results in older males having sperm of lower quality.

Unexpected toughness may mark out cancer cells in the blood

A surprising discovery about the physical properties of cancer cells could help improve a new diagnostic approach – a liquid biopsy – that detects, measures, and evaluates cancer cells in blood.

Cancer cells circulating in the bloodstream can form metastases – new tumors. Detecting these rare circulating cancer cells in a blood sample is much less invasive than a standard tumor biopsy, and could prove useful for monitoring cancer progression and detecting recurrence.

Salk scientists develop faster, safer method for producing stem cells

LA JOLLA, CA---- A new method for generating stem cells from mature cells promises to boost stem cell production in the laboratory, helping to remove a barrier to regenerative medicine therapies that would replace damaged or unhealthy body tissues.

The technique, developed by researchers at the Salk Institute for Biological Studies, allows for the unlimited production of stem cells and their derivatives as well as reduces production time by more than half, from nearly two months to two weeks.

Genetic data shows that skin cancer risk includes more than UV exposure

BETHESDA, MD – DECEMBER 4, 2012 -- It's common knowledge that excessive UV exposure from sunlight raises your chances for skin cancer, but predicting whether someone will actually develop skin cancer remains difficult. In a new research report, scientists from the University of Alabama at Birmingham (UAB) and the University of Wisconsin–Madison show that the risk for skin cancer involves numerous genetic factors including family history, ethnicity, and genetic variations specific to each individual.

Gene functional trade-offs and the evolution of pleiotropy

Gene functional trade-offs and the evolution of pleiotropy, pp. 1389-1409Frédéric Guillaume and Sarah P. OttoPleiotropy—the property of genes affecting multiple features of an organism—is often considered to be an unavoidable by-product of a gene's evolutionary history. These authors explored how the pleiotropic degree of a gene may evolve, providing clues to why pleiotropy varies among genes.