Body

Philadelphia, Pa. (December 4, 2012) – Road networks and geographic factors affecting "spatial accessibility" have a major impact on the spread of HIV across sub-Saharan Africa, according to a study published online by the journal AIDS, official journal of the International AIDS Society.

To grasp and move microscopic objects, such as bacteria and the components of living cells, scientists can harness the power of concentrated light to manipulate them without ever physically touching them.

Now, doctoral student Amr Saleh and Assistant Professor Jennifer Dionne, researchers at the Stanford School of Engineering, have designed an innovative light aperture that allows them to optically trap smaller objects than ever before – potentially just a few atoms in size.

New Rochelle, NY, December 4, 2012—About 30 million women in the U.S. have osteoporosis, with low bone mass and deteriorating bone structure that increases their risk for fractures. Racial differences in the rates of detection and management of osteoporosis were explored in a study of African American and white women published in Journal of Women's Health, a peer-reviewed publication from Mary Ann Liebert, Inc., publishers.

URBANA – A detailed annotation of the genome of T.J. Tabasco, a pig from the University of Illinois South Farms, is the outcome of over 10 years of work by an international consortium. It is expected to speed progress in both biomedical and agricultural research. U of I Vice President for Research Lawrence Schook said that the College of ACES played a crucial role in getting the work started.

December 4, 2012 – About 60% of infectious diseases are caused by viruses, bacteria and other pathogens that make the jump to humans from other species. This includes some of the most devastating disease outbreaks of the past 30 years, including HIV/AIDS, Ebola, and SARS. Despite the huge and rising toll of such diseases, many gaps remain in our understanding of how these "zoonoses" evolve, develop, and spread—gaps that must be filled if we are to succeed in preventing or at least reducing the impact of a next pandemic.

The population of the United States is getting older, due not only to aging boomers but also to a four-year increase in life expectancy from 1990 to 2010. An aging population means increased diagnosis of prostate cancer. Statistically, the older the patient at time of diagnosis, the more aggressive the disease – and also the less well the patient is likely to tolerate traditional chemotherapies. In sum, we have more, aggressive prostate cancer that can't be targeted by traditional treatments.

These results reveal how the immune system can then limit the effectiveness of some cancer chemotherapies. The researchers now intend to block the molecules responsible for negative immune system activation to increase the efficiency of chemotherapy. A clinical trial to test this hypothesis should begin very soon.

A new study released this week confirms that lions are rapidly and literally losing ground across Africa's once-thriving savannahs due to burgeoning human population growth and subsequent, massive land-use conversion. Representing the most comprehensive assessment of the state and vitality of African savannah habitat to date, the report maintains that the lion has lost 75% of its original natural habitat in Africa – a reduction that has devastated lion populations across the continent.

Evanston, Ill. (December 4, 2012) – In 2008, research showed that expressing support for Barack Obama increased people's comfort in subsequently saying or doing things that might be considered racist. Researchers argued that endorsing a black political figure made people feel as if they had "non-racist credentials" that reduced their concern about subsequently seeming prejudiced.

Philadelphia, PA, December 4, 2012 – A new study of working women has identified factors during pregnancy and postpartum that can predict pain in the joints that comprise the pelvic girdle. While 90 percent of working women in the Netherlands return to work after the birth of their first child, health issues during the postpartum period often require sick leave. Chief among these health issues is pelvic girdle pain (PGP).

Wilmington, DE – This month, Molecular Pharmaceutics reported promising findings from the Nemours Center for Childhood Cancer Research and the Materials Science and Engineering Department at the University of Delaware, about the potential for nanotechnology to deliver chemotherapeutic agents in a way that attacks cancer cells without harming healthy cells. To date, nanoparticle-based drug delivery approaches have been poorly developed for the treatment of childhood leukemia, which comprises 30% of childhood cancers.

MANHATTAN, Kan. -- A new study may help scientists produce better climate-resistant corn and other food production plants by putting a spin on the notion that we are what we eat.

Kansas State University geneticists and colleagues found that by applying a genetic-analysis method used to study and prioritize the genes in humans, it improved the likelihood of finding critical genes in food production plants. These genes control quantitate traits in plants, such as how the plants grow and when they flower.

Raising the retirement age to increase financial stability does not make men worse off psychologically in the long-run, according to a new study by Dr. Elizabeth Mokyr Horner, from the University of California, Berkeley in the US. Her work shows that individuals go through the same psychological stages as they adjust to retirement, with life satisfaction stabilizing after 70, irrespective of how old they are when they retire. The study is published online in Springer's Journal of Happiness Studies.

This study provided important data about the fertility window of women who had suffered from childhood cancer and information concerning the associated risk factors, but did not confirm the greater risk of premature menopause (before the age of 40) that was reported by the American studies.

The results were published in the review Human Reproduction of November 15.

ANN ARBOR, Mich. — A new drug demonstrated dramatic and rapid effects on prostate cancer that had spread to the bone, according to a study reported by University of Michigan Comprehensive Cancer Center researchers.

About two-thirds of patients treated with cabozantinib had improvements on their bone scans, with 12 percent seeing complete resolution of uptake on bone scan. Bone scans assess the degree to which cancer is in the bone; improvements on these scans suggest a response to the drug.