Body

Tourists face health risks from contact with captive sea turtles

LA, CA (05 February 2013). Tourists coming into contact with sea turtles at holiday attractions face a risk of health problems, according to research published today by JRSM Short Reports. Encountering free-living sea turtles in nature is quite safe, but contact with wild-caught and captive-housed sea turtles, typically through handling turtles in confined pools or through consuming turtle products, carries the risk of exposure to toxic contaminants and to zoonotic (animal to human) pathogens such as bacteria, viruses, fungi and parasites.

Paternal obesity impacts child's chances of cancer

Maternal diet and weight can impact their child's health even before birth – but so can a father's, shows a study published in BioMed Central's open access journal BMC Medicine. Hypomethylation of the gene coding for the Insulin-like growth factor 2, (IGF2),in newborns correlates to an increased risk of developing cancer later in life, and, for babies born to obese fathers, there is a decrease in the amount of DNA methylation of IGF2 in foetal cells isolated from cord blood.

The number of multiple births affected by congenital anomalies has doubled since the 1980s

The number of congenital anomalies, or birth defects arising from multiple births has almost doubled since the 1980s, suggests a new study published today (6 February) in BJOG: An International Journal of Obstetrics and Gynaecology.

The study investigates how the change in the proportion of multiple births has affected the prevalence of congenital anomalies from multiple births, and the relative risk of congenital anomaly in multiple versus singleton births.

Obesity in dads may be associated with offspring's increased risk of disease

DURHAM, N.C. -- A father's obesity is one factor that may influence his children's health and potentially raise their risk for diseases like cancer, according to new research from Duke Medicine.

The study, which appears Feb. 6 in the journal BMC Medicine, is the first in humans to show that paternal obesity may alter a genetic mechanism in the next generation, suggesting that a father's lifestyle factors may be transmitted to his children.

Obesity leads to vitamin D deficiency

Obesity can lead to a lack of vitamin D circulating in the body, according to a study led by the UCL Institute of Child Health (ICH). Efforts to tackle obesity should thus also help to reduce levels of vitamin D deficiency in the population, says the lead investigator of the study, Dr Elina Hypponen.

While previous studies have linked vitamin D deficiency with obesity, the ICH-led paper, published in the journal PLOS Medicine, sought to establish the direction of causality i.e. whether a lack of vitamin D triggers a weight gain, or whether obesity leads to the deficiency.

Steroids help reverse rapid bone loss tied to rib fractures

(Embargoed) CHAPEL HILL, N.C. – New research in animals triggered by a combination of serendipity and counterintuitive thinking could point the way to treating fractures caused by rapid bone loss in people, including patients with metastatic cancers.

A series of studies at the University of North Carolina School of Medicine found that steroid drugs, known for inducing bone loss with prolonged use, actually help suppress a molecule that's key to the rapid bone loss process. A report of the new findings appears online Feb. 5, 2013 in the journal PLOS ONE.

Plants cut the mustard for basic discoveries in metabolism

LA JOLLA, CA----You might think you have nothing in common with mustard except hotdogs. Yet based on research in a plant from the mustard family, Salk scientists have discovered a possible explanation for how organisms, including humans, directly regulate chemical reactions that quickly adjust the growth of organs. These findings overturn conventional views of how different body parts coordinate their growth, shedding light on the development of more productive plants and new therapies for metabolic diseases.

Lower proportion of Medicare patients dying in hospitals

In a study that included data on more than 800,000 Medicare beneficiaries who died between 2000 – 2009, a lower proportion died in an acute care hospital in recent years, although both intensive care unit (ICU) use and the rate of health care transitions increased during the last month of life, according to a study appearing in the February 6 issue of JAMA.

Study finds potential to match tumors with known cancer drugs

ANN ARBOR, Mich. — When it comes to gene sequencing and personalized medicine for cancer, spotting an aberrant kinase is a home run. The proteins are relatively easy to target with drugs and plenty of kinase inhibitors already exist.

New modeling approach transforms imaging technologies

WEST LAFAYETTE, Ind. – Researchers are improving the performance of technologies ranging from medical CT scanners to digital cameras using a system of models to extract specific information from huge collections of data and then reconstructing images like a jigsaw puzzle.

The new approach is called model-based iterative reconstruction, or MBIR.

Scientists discover protein that allows safe recycling of iron from old red blood cells

COLLEGE PARK, Md. – Humans survive by constantly recycling iron, a metal that is an essential component of red blood cells, but which is toxic outside of those cells. More than 90 percent of the iron in an adult human's 25 trillion life-sustaining red blood cells is recycled from worn-out cells.

Fighting fat with fat: Stem cell discovery identifies potential obesity treatment

February 5, 2013—Ottawa—Ottawa scientists have discovered a trigger that turns muscle stem cells into brown fat, a form of good fat that could play a critical role in the fight against obesity. The findings from Dr. Michael Rudnicki's lab, based at the Ottawa Hospital Research Institute, were published today in the prestigious journal Cell Metabolism.

Some omega-3 oils better than others for protection against liver disease

CORVALLIS, Ore. – Research at Oregon State University has found that one particular omega-3 fatty acid has a powerful effect in preventing liver inflammation and fibrosis – common problems that are steadily rising along with the number of Americans who are overweight.

Tendency to fear is strong political influence

It's no secret that fear is a mechanism often used in political campaigns to steer public opinion on hot-button issues like immigration and war. But not everyone is equally predisposed to be influenced by such a strategy, according to new research by Rose McDermott, professor of political science, and colleagues published in the American Journal of Political Science.

Samoan obesity epidemic starts at birth

PROVIDENCE, R.I. [Brown University] — As some Pacific island cultures have "westernized" over the last several decades, among the changes has been a dramatic increase in obesity. Researchers don't understand all the reasons why, but even a decade ago in American Samoa 59 percent of men and 71 percent of women were obese. A new Brown University study finds that the Samoan epidemic of obesity may start with rapid weight gain in early infancy.