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Found a genetic mutation causing mental retardation very similar to Angelman syndrome in Amish

Researchers from the research group in growth factors and cell differentiation at IDIBELL and the University of Barcelona (UB) have participated in an international study that has identified the genetic cause of developmental delay observed in Amish individuals in the USA. The research results have been published in the Journal of Medical Genetics.

Amish community

Nearly a third of antibiotic prescriptions for dialysis patients inappropriate

Patients who receive hemodialysis are at a significant risk of developing infections, a leading cause of hospitalization and death in this patient population. A new study highlights the need to improve antibiotic use in outpatient dialysis facilities as data shows nearly a third of antibiotic prescriptions are deemed inappropriate. The study is published in the April issue of Infection Control and Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America.

BUSM study reveals therapeutic targets to alter inflammation, type 2 diabetes

New research from Boston University School of Medicine (BUSM) reveals that B cells regulate obesity-associated inflammation and type 2 diabetes through two specific mechanisms. The study, published in the Proceedings of the National Academies of Sciences, indicates the importance of continuing to explore B cells as a therapeutic target to treat these diseases. Barbara Nikolajczyk, PhD, associate professor of microbiology at BUSM, is the study's senior author.

Sri Lankan snake study reveals new species, rich biodiversity in island country

WASHINGTON Alex Pyron's expertise is in family trees. Who is related to whom, who begat whom, how did they get where they are now. But not for humans: reptiles.

Sleator lab identifies single point mutation in Listeria monocytogenes

The bacterial foodborne pathogen, Listeria monocytogenes is the causative agent of listeriosis—a debilitating disease linked with ~2,500 illnesses and more than 500 deaths per annum in the US alone. A characteristic feature of L. monocytogenes is its ability to grow at refrigeration temperatures and in the presence of high concentrations of salt—traditional food preservation techniques, which arrest the growth of most other pathogens.

Penn study: Financial incentives affect prostate cancer treatment patterns

Philadelphia - According to a new study by researchers at the Perelman School of Medicine at the University of Pennsylvania, prostate cancer patients of urologists who own expensive radiation equipment are more likely to receive radiation treatment in lieu of surgery than patients treated by urologists without an ownership stake in the equipment.

Mystery of 'zombie worm' development unveiled

How do bone-eating worms reproduce? A new study by Norio Miyamoto and colleagues from the Japan Agency for Marine-Earth Science and Technology sheds light on this question through a detailed observation of the postembryonic development and sexual maturation of Osedax worms, also known as "zombie worms." These worms typically inhabit vertebrate bones on the seafloor. The study is published online in Springer's journal Naturwissenschaften - The Science of Nature.

4 dinosaur egg species identified in Lleida

A study headed by the Miquel Crusafont Catalan Palaeontology Institute has for the first time documented detailed records of dinosaur egg fossils in the Coll de Nargó archaeological site in Lleida, Spain. Up until now, only one type of dinosaur egg had been documented in the region.

Young pigs prefer traditional soybean diet

Des Moines, IA – Pigs aren't known for being picky, but new research shows they avoid bitter tastes when they can.

In a new study of nursery pig diets, researchers from the University of Alberta offered pigs different amounts of soybean meal, napus canola meal and juncea canola meal. They found that pigs ate more soybean meal when given a choice.

Some bacteria may protect against disease caused by stomach infection

Half of the world's human population is infected with the stomach bacteria called Helicobacter pylori, yet it causes disease in only about 10 percent of those infected. Other bacteria living in the stomach may be a key factor in whether or not H. pylori causes disease, according to a new study led by scientists at the University of California, Santa Cruz.

The nose's unheralded neighbor

Pity the poor maxillary sinuses. Those bulbous pouches on either side of the human nose are known more for trapping mucus and causing sinus infections than anything else. They were thought to be an evolutionary relic of our distant past, with little known present value.

Antibiotic-resistant strain of E. coli increasing among older adults and residents of nursing homes

Antibiotic-resistant Escherichia coli (E. coli) continues to proliferate, driven largely by expansion of a strain of E. coli know as sequence type ST131. A new study points to hospitals and long-term care facilities (LTCF) as settings in which this antibiotic-resistant strain is increasingly found. The study is published in the April issue of Infection Control and Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America.

Repairing the nose after skin cancer in just one step

ANN ARBOR, Mich. — The skin cancer growing on Carolyn Bohlmann's nose was not a very aggressive variety. But it was deep and located right on her nostril. The tricky part was not so much removing it – MOHS surgery, the procedure Bohlmann had, is a fairly common outpatient procedure.

The tricky part would be reconstructing her nostril so that it didn't lift up or droop down. It's an important cosmetic issue, but it's also critical for breathing.

Cryptic clams: U-M biologists find species hiding in plain view

ANN ARBOR— Cryptic comments seem to have an ambiguous, obscure or hidden meaning. In biology, cryptic species are outwardly indistinguishable groups whose differences are hidden inside their genes.

Two University of Michigan marine biologists have identified three cryptic species of tiny clams, long believed to be members of the same species, which have been hiding in plain view along the rocky shores of southern Australia for millions of years.

Havoc in biology's most-used human cell line

HeLa cells are the world's most commonly used human cell lines, and have served as a standard for understanding many fundamental biological processes. In a study published today in G3: Genes, Genomes and Genetics online, scientists at the European Molecular Biology Laboratory in Heidelberg, announce they have successfully sequenced the genome of a HeLa cell line. It provides a high-resolution genomic reference that reveals the striking differences between the HeLa genome and that of normal human cells. The study could improve the way HeLa cells are used to model human biology.