Body

Lower incidence of genital warts in young girls

The incidence of genital warts, or condylomata, declined by 93 per cent in girls given the HPV vaccine before the age of 14, according to a Swedish national registry study. The study was carried out by researchers at Karolinska Institutet in Sweden, and published in Journal of the National Cancer Institute.

Dwelling on stressful events can increase inflammation in the body, study finds

ATHENS, Ohio (March 13, 2013)—Dwelling on negative events can increase levels of inflammation in the body, a new Ohio University study finds.Researchers discovered that when study participants were asked to ruminate on a stressful incident, their levels of C-reactive protein, a marker of tissue inflammation, rose. The study is the first time to directly measure this effect in the body.

Scientists discover novel chemical that controls cell behavior

March 12, 2013 — Albuquerque, NM (UNM Cancer Center) — It's the spread of the original cancer tumor that kills most people. That's why cancer researchers vigorously search for drugs that can prevent metastases, the spread of cancer. The research team co-led by Angela Wandinger-Ness, PhD, and Larry Sklar, PhD, at the University of New Mexico Cancer Center has found a chemical compound that appears to control cell migration and adhesion, two important characteristics of metastatic cancer cells.

Vitamin D may lower blood pressure in African Americans

Boston – High blood pressure, a risk factor for heart attacks, heart failure and stroke, is 40 percent more common in African-Americans than in other American ethnic groups. In a new study from Brigham and Women's Hospital (BWH), along with the Dana-Farber Cancer Institute and Massachusetts General Hospital, researchers show that vitamin D supplementation may help African-Americans lower their blood pressure. The study publishes online in the March 13, 2013 edition of the American Heart Association journal Hypertension.

1 in 4 colonoscopies in Medicare patients found to be potentially inappropriate

Colonoscopy is one of the most effective cancer screening procedures available. Colon cancer grows very slowly and can be treated if caught early through screening. But, perhaps because of this success, older Americans are undergoing screening colonoscopies despite recommendations against screening in adults aged 76 and older.

More accurate, sensitive DNA test allows early identification of fungus causing WNS

MADISON, Wis., March 13, 2013 – Even after researchers studying White Nose Syndrome (WNS) established that a fungus called Geomyces destructans is at the heart of the devastating disease, detecting it depended largely on finding dead or dying bats.

Protein may alter inevitability of osteoarthritis

HOUSTON -- (March 13, 2013) – Few things in life are inevitable – death, taxes, and, if you live long enough, osteoarthritis.

Strange phallus-shaped creature provides crucial missing link

Christopher Cameron of the University of Montreal's Department of Biological Sciences and his colleagues have unearthed a major scientific discovery - a strange phallus-shaped creature they found in Canada's Burgess Shale fossil beds, located in Yoho National Park. The fossils were found in an area of shale beds that are 505 million years old.

Burgess Shale worm provides crucial missing link

Canada's 505 million year-old Burgess Shale fossil beds, located in Yoho National Park, have yielded yet another major scientific discovery – this time with the unearthing of a strange phallus-shaped creature.

Joslin scientists discover mechanism that regulates production of energy-burning brown fat

BOSTON – March 13, 2013 – Joslin scientists have discovered a mechanism that regulates the production of brown fat, a type of fat which plays an important role in heat production and energy metabolism. The findings, which appear in the upcoming issue of Nature, may lead to new therapies that increase BAT formation to treat obesity.

Tapeworm DNA contains drug weak spots

For the first time, researchers have mapped the genomes of tapeworms to reveal potential drug targets on which existing drugs could act. The genomes provide a new resource that offers faster ways to develop urgently needed and effective treatments for these debilitating diseases.

Molecule's structure reveals new therapeutic opportunities for rare diabetes

ORLANDO, Fla., March 13, 2013 – Researchers at Sanford-Burnham Medical Research Institute (Sanford-Burnham) have determined the complete three-dimensional structure of a protein called HNF-4α. HNF-4α controls gene expression in the liver and pancreas, switching genes on or off as needed. People with mature onset diabetes of the young (MODY1), a rare form of the disease, have inherited mutations in the HNF-4α protein. This first-ever look at HNF-4α's full structure, published March 13 in Nature, uncovers new information about how it functions.

New monoclonal antibody developed that can target proteins inside cancer cells

NEW YORK, MARCH 13, 2013 – Researchers have discovered a unique monoclonal antibody that can effectively reach inside a cancer cell, a key goal for these important anticancer agents, since most proteins that cause cancer or are associated with cancer are buried inside cancer cells. Scientists from Memorial Sloan-Kettering Cancer Center and Eureka Therapeutics have collaborated to create the new human monoclonal antibody, which targets a protein associated with many types of cancer and is of great interest to cancer researchers.

Polo takes the bait

KANSAS CITY, MO—A seemingly obscure gene in the female fruit fly that is only active in cells that will become eggs has led researchers at the Stowers Institute for Medical Research to the discovery of a atypical protein that lures, traps, and inactivates the powerful Polo kinase, widely considered the master regulator of cell division. Its human homolog, Polo-like kinase-1 (Plk1), is misregulated in many types of cancer.

UT study identifies ways children can meet recommended activity goals

KNOXVILLE—Despite overwhelming evidence about the benefits of physical activity for children, most American youngsters are not meeting the federal recommendation of 60 minutes a day.

A new study by a team of University of Tennessee researchers has identified specific ways—and estimated minutes for each approach—that can help children achieve the recommended daily physical activity goal.