Body

(WASHINGTON)-Transplants of blood-forming stem cells from umbilical cord blood may be an effective alternative to transplants of matched donor bone marrow stem cells to treat children with a rare, debilitating disease known as Hurler's syndrome (HS), according to results of a study published online today in Blood, the Journal of the American Society of Hematology (ASH).

TORONTO, ON — Researchers from the University of Toronto and SickKids Research Institute announced today that they have successfully mapped the genes in the fungus that causes Dutch Elm Disease.

The researchers believe this is the first time the 30 million DNA letters for the fungus Ophiostoma ulmi have been mapped. The findings, published in this week's online journal BMC Genomics, could help scientists figure out how to prevent the fungus from destroying elm trees in the future.

A virus that most people have probably never heard of, yet most of us carry, is the number 1 infectious cause of congenital birth defects. One in 750 children are born with, or develop, permanent disabilities such as hearing loss or brain damage as a result of CMV (cytomegalovirus) infection in the womb. Major research efforts are underway to combat this invidious disease.

Researchers from Cardiff University and the La Jolla Institute, California, have discovered a previously unknown cellular mechanism that could prove critical in creating a CMV vaccine.

Valdivia, Chile, and Washington, D.C.—Cancer cells break down sugars and produce the metabolic acid lactate at a much higher rate than normal cells. This phenomenon provides a telltale sign that cancer is present, via diagnostics such as PET scans, and possibly offers an avenue for novel cancer therapies. Now a team of Chilean researchers at The Centro de Estudios Científicos (CECs), with the collaboration of Carnegie's Wolf Frommer, has devised a molecular sensor that can detect levels of lactate in individual cells in real time.

Terahertz (THz) radiation, a slice of the electromagnetic spectrum that occupies the middle ground between microwaves and infrared light, is rapidly finding important uses in medical diagnostics, security, and scientific research. As scientists and engineers find evermore practical uses for this form of radiation, questions persist about its potential human health risks.

The beetle family Cerambycidae, also known as long-horned beetles or longicorns, is characterized by emblematic extremely long antennae, which are usually longer than the total body length of the animal. The family is rather rich in diversity with more than 20 000 species known, distributed worldwide. Some representatives of these bizarre-shaped beetles, are also known as serious pests with their wood-feeding larvae causing extensive damage to living trees or untreated lumber.

New Rochelle, NY, March 14, 2013—A woman's health status before pregnancy is critical for the health and wellbeing of the fetus and mother-to-be. The U.S. Centers for Disease Control and Prevention (CDC) has set Healthy People 2020 national objectives for women of reproductive age, and young women are making important gains toward achieving some of those health goals, while some trends are less encouraging, as reported in a study published in Journal of Women's Health, a peer-reviewed publication from Mary Ann Liebert, Inc., publishers.

American bullfrogs are native to eastern North America but have been transported by people to many other parts of the globe, and other parts of North America, where they have readily established populations and become an invasive alien menace to native ecosystems.

Smoking significantly increases individuals' risk of developing serious forms of urothelial carcinoma and a higher likelihood of dying from the disease, particularly for women. That is the conclusion of a recent study published in BJU International. While the biological mechanisms underlying this gender difference are unknown, the findings indicate that clinicians and society in general should focus on smoking prevention and cessation to safeguard against deadly cancers of the bladder, ureters, and renal pelvis, especially in females.

Predictability is often used synonymously with "boring," as in that story or that outcome was soooo predictable. For practioners of synthetic biology seeking to engineer valuable new microbes, however, predictability is the brass ring that must be captured. Researchers with the multi-institutional partnership known as BIOFAB have become the first to grab at least a portion of this ring by unveiling a package of public domain DNA sequences and statistical models that greatly increase the reliability and precision by which biological systems can be engineered.

ANN ARBOR, Mich. – For those with irritable bowel syndrome who wonder if stress aggravates their intestinal disorder, a new University of Michigan Health System study shows it's not all in their head.

Researchers revealed that while stress does not cause IBS, it does alter brain-gut interactions and induces the intestinal inflammation that often leads to severe or chronic belly pain, loss of appetite and diarrhea.

Mountain View, Calif. – March 14, 2013 – In the largest ever genome-wide association study on myopia, 23andMe, the leading personal genetics company, identified 20 new genetic associations for myopia, or nearsightedness. The company also replicated two known associations in the study, which was specific to individuals of European ancestry. The study included an analysis of genetic data and survey responses from more than 50,000 23andMe customers and demonstrates that the genetic basis of myopia is complex and affected by multiple genes.

Bangkok, 14 March 2013. CITES plenary today accepted Committee recommendations to list five species of highly traded sharks under the CITES Appendices, along with those for the listing of both manta rays and one species of sawfish. Japan, backed by Gambia and India, unsuccessfully challenged the Committee decision to list the oceanic whitetip shark, while Grenada and China failed in an attempt to reopen debate on listing three hammerhead species. Colombia, Senegal, Mexico and others took the floor to defend Committee decisions to list sharks.

BANGKOK -- March 14, 2013 -- The following statement was issued today by WCS President and CEO Cristian Samper:

Scientists already knew that some social bee species warn their conspecifics when detecting the presence of a predator near their hive, which in turn causes an attack response to the possible predator. Researchers at the University of Tours (France) in collaboration with the Experimental Station of Arid Zones of Almeria (Spain) have now demonstrated that they also use chemical signals to mark those flowers where they have previously been attacked.