Body

Young vessels rejuvenate aged insulin-producing beta cells

A recent study published in the journal PNAS shows that young capillary vessels rejuvenate aged pancreatic islets. The finding challenges prevailing views on the causes of age-dependent impaired glucose balance regulation, a condition that often develops into diabetes type 2. The international research team behind the study now suggests that targeting inflammation and fibrosis in the small blood vessels of the pancreatic islets may offer a new way of treatment for age-dependent dysregulation of blood glucose levels.

First genetic-based tool to detect circulating cancer cells in blood

Metastasis is bad news for cancer patients. Northwestern University scientists now have demonstrated a simple but powerful tool that can detect live cancer cells in the bloodstream, potentially long before the cells could settle somewhere in the body and form a dangerous tumor.

Why lizards have bird breath

SALT LAKE CITY, Nov. 17, 2014 - Whether birds are breathing in or out, air flows in a one-directional loop through their lungs. This pattern was unexpected and for decades, biologists assumed it was unique to birds, a special adaptation driven by the intense energy demands of flight.

New advance in cryopreservation could change management of world blood supplies

CORVALLIS, Ore. - Engineers at Oregon State University have identified a method to rapidly prepare frozen red blood cells for transfusions, which may offer an important new way to manage the world's blood supply.

It's already possible to cryopreserve human red blood cells in the presence of 40 percent glycerol, but is rarely done because of the time-consuming process to thaw and remove the glycerol from the blood. This can take an hour or more and makes it logistically difficult to use frozen blood.

As temperatures rise, soil will relinquish less carbon to the atmosphere than predicted

Here's another reason to pay close attention to microbes: Current climate models probably overestimate the amount of carbon that will be released from soil into the atmosphere as global temperatures rise, according to research from the US Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab).

Fruit flies learn from others

Fruit flies do not always conform to the norm. When female fruit flies have to decide where to lay their eggs, they take their lead from what they see most others in their group do. However, some do take their personal preferences into account. So says Marine Battesti of the Université Paris-Sud in France, lead author of a study in Springer's journal Behavioral Ecology and Sociobiology.

Advances in electron microscopy reveal secrets of HIV and other viruses

UC Davis researchers are getting a new look at the workings of HIV and other viruses thanks to new techniques in electron microscopy developed on campus.

The envelope (or Env) protein of HIV is a key target for vaccine makers: it is a key component in RV144, an experimental vaccine that is so far the only candidate to show promise in clinical trials. Also called gp120, the Env protein associates with another protein called gp41 and three gp120/gp41 units associate to form the final trimeric structure. The gp120 trimer is the machine that allows HIV to enter and attack host cells.

Businesses can help preserve endangered species with small landscape changes

Raptors, or birds of prey, some of which are endangered species, typically live in environments that provide natural land cover, such as forests and grasslands. Protecting endangered raptor species helps maintain food chain balance and prevents overpopulation of common raptor prey, such as snakes and rodents. As more businesses are built on the edges of urban areas, land where raptors once lived becomes industrialized, which raises concerns about the consequences of habitat destruction on raptor populations.

Newly discovered hormone with potential treatment for obesity, type 2 diabetes, liver disease

ANN ARBOR -- Researchers at the University of Michigan have discovered how a previously unknown hormone serves as a messenger from fat cells to the liver and are investigating the potential of developing a new treatment for metabolic disorders.

Middle managers and hermit crabs

RIVERSIDE, Calif. (http://www.ucr.edu) -- Ideas from mid-level managers that can benefit an organization are less likely to be passed up to superiors as hierarchy in the organization increases, according to a just published paper by an assistant professor at the University of California, Riverside.

New protocol for imaging patients with Ebola

In a breakthrough that could substantially improve physicians' ability to rapidly evaluate patients with suspected Ebola, radiologists at Emory University Hospital have devised a protocol for obtaining chest radiographs using portable computed radiography. The protocol not only limits the exposure of personnel and equipment to body fluids, it also minimizes the risk of contaminants leaving the isolation unit by use of thorough decontamination procedures.

The secret life of anti-cancer drugs

The public is bombarded with news of exciting developments in cancer research every day, with new anti-cancer drugs greeted with excitement.

But what happens to these drugs? When do they become accessible to cancer patients - if at all?

In a new review published in ecancermedicalscience, researchers trace the journey anti-cancer drugs take between discovery and clinical practice.

Diarrhea and candidiasis associated with common antibiotic amoxicillin

Diarrhea and candidiasis can result from taking the common antibiotic treatments, amoxicillin and amoxicillin-clavulanic acid, although harms may be underreported, according to a study published in CMAJ (Canadian Medical Association Journal).

Reprogramming cells, long term

Harvard Stem Cell Institute (HSCI) researchers, representing five Harvard departments and affiliated institutions as well as the Massachusetts Institute of Technology (MIT), have demonstrated that adult cells, reprogrammed into another cell type in a living animal, can remain functional over a long period.

UTHealth smoking study: Financial incentives double quit rates

HOUSTON - (Nov. 17, 2014) - Offering small financial incentives doubles smoking cessation rates among socioeconomically disadvantaged smokers, according to research from The University of Texas Health Science Center at Houston (UTHealth). The findings were published last week in the American Journal of Public Health.