Body

A bird's-eye view of the protein universe

Each cell contains thousands of proteins, each one of which bears a unique signature. All proteins, distinct in shape and function, are built from the same amino acid strings. Many proteins are vital, as evidenced by the plethora of diseases linked to their absence or malfunction. But how exactly did proteins first come to be? Do they all share a single common ancestor? Or did proteins evolve from many different origins?

Shift in gut bacteria observed in fiber supplement study may offer good news for weight loss

URBANA, Ill. - Most Americans don't get the daily recommended amount of fiber in their diet, though research has shown that dietary fiber can cause a shift in the gut toward beneficial bacteria, reducing the risk of colon cancer, type 2 diabetes, and other diseases. A new study from the University of Illinois shows that two specific functional fibers may also have the potential to assist in weight loss when made part of a long-term, daily diet.

As elephants go, so go the trees

GAINESVILLE, Fla. --- Overhunting has been disastrous for elephants, but their forest habitats have also been caught in the crossfire.

A first-of-its-kind study led by researchers at the University of Florida shows that the dramatic loss of elephants, which disperse seeds after eating vegetation, is leading to the local extinction of a dominant tree species, with likely cascading effects for other forest life.

Their work shows that loss of animal seed dispersers increases the probability of tree extinction by more than tenfold over a 100-year period.

Some flu viruses potentially more dangerous than others

WASHINGTON, DC - November 18, 2014 - Certain subtypes of avian influenza viruses have the potential to cause more severe disease in humans than other avian influenza subtypes and should be monitored carefully to prevent spread of disease, according to a study published this week in mBio®, the online open-access journal of the American Society for Microbiology.

Combined strategies help patients with adverse heparin reaction before heart surgery

(WASHINGTON, November 18, 2014) - New evidence suggests that therapeutic plasma exchange and appropriate blood testing could help patients who are in urgent need of heart surgery, but have a history of an adverse reaction to the blood thinner heparin, according to a study, published online today in Blood, the Journal of the American Society of Hematology (ASH).

Going against the flow

Mycoplasma gallisepticum causes chronic respiratory disease in birds. The illness particularly affects domestic chicken and turkey flocks. The bacteria are especially life-threatening for the animals when they occur in combination with other infections. In order to control the spread of the disease, poultry farms in the EU must be proven free from Mycoplasma gallisepticum or face being closed.

The role DNA methylation plays in aging cells

WINSTON-SALEM, N.C. - Nov. 18, 2014 - Although every person's DNA remains the same throughout their lives, scientists know that it functions differently at different ages.

As people age, drastic changes occur in their DNA methylation patterns, which are thought to act as a "second code" on top of the DNA that can lock genes in the on or off position. However, what the consequences of these changes are remains a mystery.

Herbs and spices enhance heart health as well as flavor

Spices and herbs are rich in antioxidants, which may help improve triglyceride concentrations and other blood lipids, according to Penn State nutritionists.

Triglyceride levels rise after eating a high-fat meal -- which can lead to an increased risk of heart disease. If a high-antioxidant spice blend is incorporated into the meal, triglyceride levels may be reduced by as much as 30 percent when compared to eating an identical meal without the spice blend. The spiced meal included garlic powder, rosemary, oregano, cinnamon, cloves, paprika, turmeric, ginger and black pepper.

Cell study sheds light on diseases caused by immune system fault

Scientists have discovered how a gene mutation can lead to diseases that occur when the immune system attacks the body by mistake.

Understanding how these mechanisms work could help scientists to develop new treatments for autoimmune diseases such as Lupus and neurodegenerative conditions including Motor Neurone Disease.

Ebola surveillance may become quicker and cheaper

A new method for examining the Ebola virus genome could make surveillance quicker and cheaper for West African nations, and help detect new forms of the virus. The detailed procedure is being shared with the research community along with the study paper, which is freely available in the open access journal Genome Biology.

Research provides new insight into gluten intolerance

Celiac disease patients suffer from gluten intolerance and must adjust to a life without gluten from food sources like wheat, rye and barley. There is no treatment of the disease except lifelong gluten-free diet, but now a Danish/Norwegian research team publishes new research, that may lead to the development of a drug against the disease.

Age matters: Young larvae boost pollen foraging in honey bees

Toddlers and tweens have very different needs, which influence how parents provide for them. The same is true in honey bees, but instead of communicating their needs via language, honey bee larvae emit chemical signals called pheromones that influence the behavior of their caregivers.

Avoiding skin graft rejection: It's possible!

A research team bringing together José Cohen and Philippe Grimbert (Inserm Unit 955/Université Paris Est Créteil [UPEC] and the Centre for Clinical Investigation - Biotherapies 504 [CIC-BT 504]), and their collaborators at Institut Curie and AP-HP (George Pompidou European Hospital) has succeeded in finding a combination of drugs that reduces the risk of rejection following a skin graft. When tested in mice, this treatment seems effective, since no sign of rejection is observed nearly 30 days after transplantation.

New measurement of HDL cholesterol function provides information about cardiovascular risk

DALLAS - November 18, 2014 - Groundbreaking research from UT Southwestern Medical Center shows that cholesterol efflux capacity (cholesterol efflux), which measures HDL cholesterol function, appears to be a superior indicator of cardiovascular risk and a better target for therapeutic treatments than standard measurements of HDL. Current measurement methods reflect only the circulating levels of HDL and not the functional properties of this lipoprotein.

Soy spells fewer hot flashes for certain women

CLEVELAND, Ohio (November 17, 2014)--Does soy in the diet help with hot flashes? It does, but only for women whose bodies can produce the soy metabolite equol, reports a study of American women just published online in Menopause, the journal of The North American Menopause Society. About 20% to 50% of North American and European women have this ability.