Body

USC researchers identify key mechanism that occurs at the inception point of many human lymphomas

Researchers at the Keck School of Medicine of the University of Southern California (USC) have explained how certain key mutations occur in human lymphomas—a process that has, until now, remained a mystery.

The findings of the study, published in the Dec. 12 issue of the journal Cell, will have a significant impact on future study of how human lymphoma occurs.

Researcher nabs 'doubly magic' tin isotope

EAST LANSING, Mich. — With help from newly developed equipment designed and built at Michigan State University, MSU researchers have been able to make first-of-its-kind measurements of several rare nuclei, one of which has been termed a "holy grail" of experimental nuclear physics.

The discoveries, made at MSU's National Superconducting Cyclotron Laboratory using an isotope purification device, will help to refine theoretical models about how elements are created in the cosmos. Until now, this was beyond the technical reach of nearly all of the world's nuclear science facilities.

Use weights, not aerobics, to ease back pain

People who use weight training to ease their lower back pain are better off than those who choose other forms of exercise such as jogging, according to a University of Alberta study.

The study, done in conjunction with the University of Regina, showed a 60 per cent improvement in pain and function levels for people with chronic backache who took part in a 16-week exercise program of resistance training using dumbbells, barbells and other load-bearing exercise equipment.

Hawaiian honeyeaters' long-lost relatives found

Despite appearances, Hawaii's five species of recently extinct songbirds known as honeyeaters bore no close relationship at all to the honeyeaters found in Australia and New Guinea, according to a genetic analysis reported online on December 11th in Current Biology, a Cell Press publication. Rather, similarities in the way the two groups of birds act and look – including their long bills and brush-tipped tongues specially adapted for gathering nectar – arose independently in the two geographical regions.

New cause of heart arrhythmia found

A new study shows that atrial fibrillation--the most common form of sustained heart arrhythmia--can be caused in an unexpected way. Researchers report in the December 12th issue of the journal Cell, a Cell Press publication, the first evidence that a rare and particularly severe form of the disease stems from a gene involved in shuttling other molecules in and out of the cell nucleus, where the DNA that serves as the blueprint for life is housed.

Scripps Research scientists watch membrane fission in real time

LA JOLLA, CA, December 9, 2008— Researchers at The Scripps Research Institute have solved one of biology's neatest little tricks: they have discovered how a cell's outer membrane pinches a little pouch from itself to bring molecules outside the cell inside—without making holes that leak fluid from either side of the membrane.

In the cover story of the December 26 issue of the journal Cell, the scientists describe creating a system in which they can watch, in real time under a light microscope, cell membranes bud and then pinch off smaller sack-like "vesicles."

Smithsonian scientists rearrange Hawaii's bird family tree

A group of five endemic and recently extinct Hawaiian songbird species were historically classified as "honeyeaters" due to striking similarities to birds of the same name in Australia and neighboring islands in the South Pacific.

Rare disease provides clues about enzyme role in arrhythmias

A University of Iowa study provides insight into a calcium-sensing enzyme already known to play a role in irregular heartbeats and other critical functions. The researchers showed that the enzyme, calmodulin kinase II (CaM kinase II), contributes to arrhythmia in an extremely rare disease called Timothy syndrome and that inhibiting the enzyme prevents irregular heartbeats.

EPA and USDA should create new initiative to better monitor nutrients

WASHINGTON --The U.S. Environmental Protection Agency and U.S. Department of Agriculture should jointly establish a Nutrient Control Implementation Initiative (NCII) to learn more about the effectiveness of actions meant to improve water quality throughout the Mississippi River basin and into the northern Gulf of Mexico, says a new report from the National Research Council.

Mayo Clinic researchers find tamoxifen's power comes from endoxifen

SAN ANTONIO - Mayo Clinic researchers have discovered that a chemical known as endoxifen appears to be the primary metabolite responsible for the effectiveness of tamoxifen in treating breast cancer, and that it works against cancer in an entirely unexpected way.

There's a life-saving medical device sitting on your sink

Hospital-borne infections are a serious risk of a long-term hospital stay, and ventilator-associated pneumonia (VAP), a lung infection that develops in about 15% of all people who are ventilated, is among the most dangerous. With weakened immune systems and a higher resistance to antibiotics, patients who rely on a mechanical ventilator can easily develop serious infections — as 26,000 Americans do every year.

Thanks to a proven new clinical approach developed by Tel Aviv University nurses, though, there is a new tool for stopping the onset of VAP in hospitals.

Estrogen pills can benefit women with metastatic breast cancer

In the animal world, bigger isn't necessarily better

TORONTO, ON. – Shocking new research shows size isn't always an advantage in the animal world, shattering a widely-held belief that bigger is better.

Michael Kasumovic, a former University of Toronto Scarborough PhD student, examined Australian Redback male spiders to determine whether the larger ones had an edge in achieving mating success and producing offspring.

Boy or girl? It's in the father's genes

A Newcastle University study involving thousands of families is helping prospective parents work out whether they are likely to have sons or daughters.

The work by Corry Gellatly, a research scientist at the university, has shown that men inherit a tendency to have more sons or more daughters from their parents. This means that a man with many brothers is more likely to have sons, while a man with many sisters is more likely to have daughters.

Sweetened beverage consumption increases in the US

Over the past two decades, the number of adults consuming sugar-sweetened beverages such as soft drinks, fruit drinks and punches has increased dramatically, according to a study led by researchers at the Johns Hopkins Bloomberg School of Public Health. Researchers examined changes over the past two decades in sugar-sweetened beverage consumption based on nationally representative survey data, and found that sugar-sweetened beverages comprise a significant source of total daily beverage intake and are the largest source of beverage calories consumed daily.