Alaska's Tongass and Chugach National Forests, which contain some of the world's largest remaining tracts of intact temperate rainforest, contribute an average of 48 million salmon a year to the state's commercial fishing industry, a new USDA Forest Service-led study has found. The average value of these "forest fish" when they are brought back to the dock is estimated at $88 million per year.

Scientists suggest a new strategy that uses induced pluripotent stem cells (iPSCs) to regulate immune reaction to transplanted tissues.

The team, led by Professor Ken-ichiro Seino of Hokkaido University's Institute for Genetic Medicine, found that thymic epithelium cells derived from mouse induced pluripotent stem cells (iPSCs) can regulate immune response to skin grafts, extending their survival.

Boulder, Colo., USA: Recent seafloor drilling has revealed that the “hidden continent

” of Zealandia—a region of continental crust twice the size of India
submerged beneath the southwest Pacific Ocean—experienced dramatic
elevation changes between about 50 million and 35 million years ago. New
findings from this expedition, published today in Geology, propose
this topographic upheaval may have been due to a widespread reactivation of

Health insurance costs weigh heavily on the minds of many middle-aged adults, and many are worried for what they'll face in retirement or if federal health policies change, according to a new study just published in JAMA Network Open.

A population of microorganisms living in our intestine, known as the gut microbiota, plays a crucial role in controlling our metabolism and reducing the risk of conditions such as obesity and diabetes.

In 20 - 40% of patients with cancer, metastasis (the development of secondary tumors) in the central nervous system (CNS) occurs. CNS metastatis impacts negatively on a patient's quality of life, and is associated with a poor health prognosis. In a form of cancer known as ALK-rearranged non-small-cell lung cancer (NSCLC), CNS metastatis is known to persist when drugs targeting primary tumors are used. Now, Seiji Yano from Kanazawa University and colleagues have investigated the origins for the resistence to such drugs, and tested a new therapeutic strategy on a mouse model.

The Clostridium difficile pathogen takes its name from the French word for "difficult." A bacterium that is known to cause symptoms ranging from diarrhea to life-threatening colon damage, C. difficile is part of a growing epidemic of concern for the elderly and patients on antibiotics.

Outbreaks of C. difficile-infected cases have progressively increased in Western countries, with 29,000 reported deaths per year in the United States alone.

Chronic pain, or inflammation, is believed to be one of the major factors in the onset of major depressive disorder. Therefore, to better understand what happens physiologically during depression, scientists have long studied several metabolic processes or "pathways" related to inflammation. One of these pathways, called the kynurenine pathway, is the principal pathway involved in metabolizing the amino acid tryptophan.

A new reaction system can detect X-rays at the highest sensitivity ever recorded by using organic molecules. The system, developed by researchers at Nara Institute of Science and Technology (NAIST), Ikoma, Japan, and Centre National de la Recherche Scientfique (CNRS), Toulouse, France, involves the cycloreversion of terarylene, causing the molecule to switch reversibly between colorless and blue isoforms in the presence or absence of X-rays. With detection at safe doses, this reaction system is expected to detect even the faintest X-rays levels considered dangerous.

To classify the most important ecological and biological components of the deep sea, an international team including Professor Roberto Danovaro from Stazione Zoologica Anton Dohrn Napoli, Italy and Dr Moriaki Yasuhara from The Swire Institute of Marine Science (SWIMS) and School of Biological Sciences, The University of Hong Kong (HKU) sent a questionnaire-based survey to the world's leading deep-sea scientists around the world.