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Applying bioinformatics to resolve biological problems. This is the objective of the research group of the University of Malaga "BI4NEXT", which, in one of its latest studies, developed in the Supercomputing and Bioinnovation Center (SCBI) based on biobank samples, has identified new biomarkers for the diagnosis, prognosis and even treatment of lung cancer.
Children of mothers prescribed macrolide antibiotics during early pregnancy are at an increased risk of major birth defects, particularly heart defects, compared with children of mothers prescribed penicillin, finds a study published by The BMJ today.
The researchers say these findings show that macrolides should be used with caution during pregnancy and if feasible alternative antibiotics should be prescribed until further research is available.
What The Study Did: More than 925,000 adults in the National Cancer Database with a new diagnosis of invasive breast, colon or lung cancer were included in this observational study that examined how Medicaid expansion under the Patient Protection and Affordable Care Act (ACA) was associated with insurance status, cancer stage at diagnosis and timely treatment.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
Researchers at Karolinska Institutet in Sweden have carried out the first randomised trial of civilians with acute conflict-related wounds at two hospitals in areas affected by armed conflict. The study, which is published in The Lancet Global Health, shows that a new, more costly method of wound treatment is not more effective than standard treatment. The researchers hope to inspire new research projects in conflict zones that could improve the care for these vulnerable patients.
More than 10,000 uninsured patients sought care at Texas emergency departments for lifesaving kidney dialysis in 2017, incurring more than $21.8 million in hospital costs, according to researchers from The University of Texas Health Science Center at Houston (UTHealth).
The study, which was led by experts at the University of Nottingham, with collaborators from City, University of London and De Montfort Universities, and was funded by the National Institute for Health and Clinical Excellence, looked at six geographical areas in England.
Findings from the study showed that in a quarter of local maternity services in England, MUs are not available, or women have trouble getting information or access to them.
A large investment of at least US$3.9 billion needed to meet the World Health Organization's (WHO) target for the elimination of Hepatitis C virus (HCV) in Pakistan could deliver huge benefits in terms of lives saved and reduced ill health, according to University of Bristol led research published in The Lancet Global Health today [19 February].
In complex surgery, does a correlation exist between the volume of services provided per hospital or per surgeon and the quality of the treatment results? This is the question addressed in eight commissions on minimum volumes awarded in Germany by the Federal Joint Committee (G-BA) to the Institute for Quality and Efficiency in Health Care (IQWiG). The IQWiG report is now available for the fourth indication investigated, the surgical treatment of breast cancer.
Leesburg, VA, February 19, 2020--Two MRI findings--joint capsule edema and thickness at the axillary recess, specifically--proved useful in predicting stiff shoulder in patients with rotator cuff tears, according to an ahead-of-print article in the May issue of the American Journal of Roentgenology (AJR).
Studying 106 patients with small to large (
For women with hormone receptor-positive breast cancer, long-term endocrine therapy can greatly reduce the risk of recurrence. Many women, especially those in underserved populations, do not continue treatment, however. A new Psycho-Oncology study uncovers some of the factors that may be involved.
A study of teenage girls' selfie-taking behaviors found that taking and sharing selfies on social media is not linked to poor body image or appearance concerns.
However, when adolescent girls spend too much time agonizing over which photo of themselves to post, or rely heavily on editing apps to alter their images, there may be cause for concern.
Maternal obesity may increase a child’s risk for attention-deficit hyperactivity disorder (ADHD), according to an analysis by researchers from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), part of the National Institutes of Health.
The objective of this study was to compare the safety and antitumor activity of F14512 and etoposide phosphate in dogs with spontaneous non-Hodgkin lymphoma and to investigate the potential benefit of F14512 in P-glycoprotein overexpressing lymphomas.
Subgroup analysis of dogs with Pgp-overexpressing NHL showed a significant improvement in PFS in dogs treated with F14512 compared with etoposide phosphate.
F14512 showed strong therapeutic efficacy against spontaneous NHL and exhibited a clinical benefice in Pgp-overexpressing lymphoma superior to etoposide phosphate.
With recent developments in prenatal screening, more parents are expected to receive a Down syndrome diagnosis before the birth of their child, which can involve complex decision-making for many. To understand what such a diagnosis means for parents who decide to continue their pregnancy and prepare for a child with Down syndrome (DS), the Dutch Down Syndrome Foundation surveyed 212 parents of children with DS born between 2010 and 2016.
TUCSON, Ariz. - As she jumped to head a soccer ball during her junior year of college, Kelly Farrell collided skulls with a teammate. She later was diagnosed with a concussion, which proved to be severely debilitating.
"I had a lot of trouble concentrating in school and class," said Farrell, a physical therapist and Tucson native, who experienced a constant headache for two days after her concussion. Even after the initial pain subsided, her headache was reactivated by noise, bright light and studying on her computer.