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Decoding the effect of body mass index on breast cancer
Medical researchers at Flinders University have established a new link between high body mass index (BMI) and breast cancer survival rates -- with clinical data revealing worse outcomes for early breast cancer (EBC) patients and improved survival rates in advanced breast cancer (ABC).
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Move over CRISPR, the retrons are coming
Researchers at the Wyss Institute for Biologically Inspired Engineering at Harvard University have created a new gene editing tool called Retron Library Recombineering (RLR) that can generate up to millions of mutations simultaneously, and "barcodes" mutant bacterial cells so that the entire pool can be screened at once. It can be used in contexts where CRISPR is toxic or not feasible, and results in better editing rates.
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The novel coronavirus' spike protein plays additional key role in illness
Salk researchers and collaborators show how the novel coronavirus spike protein damages cells, confirming COVID-19 as a primarily vascular disease.
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Study finds similar long-term outcomes for mechanically-ventilated COVID-19 patients
A new study, presented today at the AATS 101st Annual Meeting, found that severely ill COVID-19 patients treated with ECMO did not suffer worse long-term outcomes than other mechanically-ventilated patients.
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Clinically viable blood test for donor-derived cell-free DNA
Multi-site study of pediatric and adult patients shows cfDNA holds promise as a non-invasive biomarker to assess for risk of rejection following heart transplantation.
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Care teams differ for Black, white surgical patients in the same hospitals
A new study finds Black patients are more likely to die after their heart bypass surgery if they're at a hospital where some care teams see mostly white patients and others see mostly Black patients. On the other hand, mortality rates are comparable between Black and white patients after heart bypass surgery when the teams of health care providers at their hospitals all care for patients of all races.
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New genetic target for blood cancer treatment
Researchers have identified a vulnerability in some cases of acute myeloid leukaemia that could be harnessed for targeted treatment of these poor-prognosis cancers
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WIN's DDPP biomarker to guide cancer therapy and predict response duration
The Worldwide Innovative Network - WIN Consortium in personalized cancer medicine announces the publication in NPJ Precision Oncology of the Digital Display Precision Predictor (DDPP) global biomarker prototype to guide the selection of targeted therapy and predict the progression-free survival for cancer patients. Read here: https://rdcu.be/cjz6h
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Dalian coherent light source reveals oxygen production from three-body photodissociation of water
The researchers from DICP of CAS revealed oxygen production from the three-body photodissociation of water molecule using the Dalian Coherent Light Source.
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New brain-like computing device simulates human learning
Researchers developed new synaptic transistors that can mimic the human brain's plasticity by simultaneously processing and storing data. After connecting transistors into a device, researchers conditioned it to associate light with pressure -- similar to how Pavlov's dog associated a bell with food.
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NIH study identifies diverse spectrum of neurons that govern movement
In a mouse study, National Institutes of Health researchers have identified and mapped a diverse spectrum of motor neurons along the spinal cord.
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Researchers develop chip that improves testing and tracing for COVID-19
Jeremy Edwards, director of the Computational Genomics and Technology (CGaT) Laboratory at The University of New Mexico, and his colleagues at Centrillion Technologies in Palo Alto, Calif. and West Virginia University, have developed a chip that provides a simpler and more rapid method of genome sequencing for viruses like COVID-19.
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New view of species interactions offers clues to preserve threatened ecosystems
Scientists from around the world have produced a new analysis--believed to be the most detailed study of specialized ecological data from global forests--that is furthering science's understanding of species interactions and how diversity contributes to the preservation of ecosystem health.
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Latest observations by MUSER help clarify solar eruptions
Prof. YAN Yihua and his research team from the National Astronomical Observatories of the Chinese Academy of Sciences (NAOC) recently released detailed results of observations by the new generation solar radio telescope--Mingantu Spectral Radio Heliograph (MUSER)--from 2014 to 2019.
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The Lancet: Many more people could benefit from blood pressure-lowering medication
Blood pressure-lowering medication can prevent serious cardiovascular conditions such as strokes, heart failure and heart attacks even in adults with normal blood pressure, according to new research published in The Lancet.
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Northern forest fires could accelerate climate change
New research shows that the global models used to project how Earth's climate will change in the future underestimate the impact of forest fires and drying climate on forests' ability to capture and store atmospheric carbon.
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A silver lining for extreme electronics
Michigan State researchers are building tougher circuits to help withstand the grueling demands of energy production, space exploration and more.
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Guidance on treatment for rare blood clots and low platelets related to COVID-19 vaccine
Last Friday, the Centers for Disease Control and Prevention (CDC) and the U.S. Food & Drug Administration (FDA) lifted the pause in administration of the Johnson & Johnson (Janssen) COVID-19 vaccine in the U.S.
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Study: Older adults found resilience during pandemic through community, human connection
Older adults were significantly affected by isolation and stress during Oregon's initial COVID-19 lockdown last spring, but they were also able to find connection and meaning in community, new hobbies and time for themselves, a recent Oregon State University study found.
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Icebreaker's cyclone encounter reveals faster sea ice decline
An icebreaker unexpectedly in the path of an Arctic cyclone allowed researchers to unravel why sea ice declines during and after a cyclone. For the first time ever, scientists were able to show that cyclone-triggered processes within the Arctic Ocean melt sea ice from below.
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