NIH scientists find promising biomarker for predicting HPV-related oropharynx cancer

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Researchers have found that antibodies against the human papillomavirus (HPV) may help identify individuals who are at greatly increased risk of HPV-related cancer of the oropharynx, which is a portion of the throat that contains the tonsils.

1 step closer to a vaccine for a common respiratory disease

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RSV is a common cause of respiratory infection, but there is no vaccine available. It causes flu-like symptoms in healthy adults, but becomes life-threatening in young children and the elderly. It is estimated to cause over 100 000 deaths yearly worldwide.

The teams of Research Director Sarah Butcher (Institute of Biotechnology, University of Helsinki) and Professor Ari Helenius (ETH Zurich) have now solved the three-dimensional structure of RSV.

New way to improve antibiotic production

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An antibiotic has been found to stimulate its own production. The findings, to be published in PNAS, could make it easier to scale up antibiotic production for commercialisation.

Scientists Dr Emma Sherwood and Professor Mervyn Bibb from the John Innes Centre were able to use their discovery of how the antibiotic is naturally produced to markedly increase the level of production.

"We have shown for the first time that an antibiotic with clinical potential can act as signalling molecule to trigger its own synthesis," said Professor Bibb.

Timeline reforms increase initiation speed of NCI sponsored clinical trials

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The National Cancer Institute (NCI) and investigators have reduced the deadlines for initiation of trials with the goal of reaching more patients in need of new treatments, according to a study published June 17 in the Journal of the National Cancer Institute.

Eating more red meat associated with increased risk of Type 2 diabetes

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Eating more red meat over time is associated with an increased risk of type-2 diabetes mellitus (T2DM) in a follow-up of three studies of about 149,000 U.S. men and women, according to a report published Online First by JAMA Internal Medicine, a JAMA Network publication.

Study details age disparities in HIV continuum of care

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Age disparities exist in the continuum of care for patients with the human immunodeficiency virus (HIV) with people younger than 45 years less likely to be aware of their infection or to have a suppressed viral load, according to a report published Online First by JAMA Internal Medicine, a JAMA Network publication.

Parental cultural attitudes and beliefs associated with child's media viewing and habits

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Differences in parental beliefs and attitudes regarding the effects of media on early childhood development may help explain increasing racial/ethnic disparities in child media viewing/habits, according to a study by Wanjiku F. M. Njoroge, M.D., of Seattle Children's Hospital and the University of Washington, Seattle, and colleagues. (Online First)

Poor eating behaviors may put preschoolers at risk for later health problems

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TORONTO, June 17, 2013—How kids eat their food may turn out to be just as important as what they eat, according to a new study out of St. Michael's Hospital.

The study, led by Dr. Nav Persaud, a family physician, found a significant association between poor eating habits in kids ages three to five and their levels of non-HDL – or "bad" – cholesterol, putting them at risk for cardiovascular disease later in life.

The paper appeared online in the Canadian Medical Association Journal today.

NYSCF and Columbia researchers demonstrate use of stem cells to analyze causes, treatment of diabetes

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NEW YORK, NY (June 17, 2013) – A team from the New York Stem Cell Foundation (NYSCF) Research Institute and the Naomi Berrie Diabetes Center of Columbia University has generated patient-specific beta cells, or insulin-producing cells, that accurately reflect the features of maturity-onset diabetes of the young (MODY).

New compound excels at killing persistent and drug-resistant tuberculosis

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LA JOLLA, CA – June 17, 2013 – An international team led by scientists at The Scripps Research Institute (TSRI), the Howard Hughes Medical Institute and Albert Einstein College of Medicine of Yeshiva University has identified a highly promising new anti-tuberculosis compound that attacks the tuberculosis (TB) bacterium in two different ways.