Body

Cancer Research UK scientists have discovered that testing skin cancer patients' blood for tumour DNA could help predict the chances of an aggressive cancer returning.

Published in the Annals of Oncology* today (Wednesday), the findings could pave the way to identifying patients who are most at risk of their disease returning, and who might benefit from new immunotherapy treatments.

A team of surgeons at Mount Sinai Beth Israel, led by Hyunsuk Suh, MD, Assistant Professor in the Department of Surgery at the Icahn School of Medicine at Mount Sinai, have performed the first robot-assisted radical neck dissection in the United States using the bilateral axillo-breast approach (BABA), a surgery that involves removing all of the lymph nodes on one side of the neck. The results were published today in the journal VideoEndocrinology.

Multiple myeloma is the second most common blood cancer in the United States. Thirty to 50 percent of multiple myeloma patients have extra copies of the gene that encodes the enzyme ADAR1. Using a database of multiple myeloma patient samples and information, researchers at University of California San Diego School of Medicine found that high ADAR1 levels correlate with reduced survival rates. They also determined that blocking the enzyme reduces multiple myeloma regeneration in experimental models derived from patient cancer cells.

Rates of diabetes and obesity, which are important risk factors for Alzheimer's disease, also decrease if there is a particular amount of lithium in the water, says the study, published recently in the Journal of Alzheimer's Disease.

Postdoctoral fellow Val Fajardo and Rebecca MacPherson, Assistant Professor in the Department of Health Sciences, collected statistics on various lithium levels in drinking water in 234 counties across Texas.

ST. LOUIS -- In early results published in The Lancet, researchers report that an investigational Zika vaccine was well-tolerated and stimulated potentially protective immune responses in three phase 1 clinical trials, one of which was conducted at Saint Louis University. More than 90 percent of study volunteers in the 3 trials who received the investigational vaccine demonstrated an immune response to Zika virus.

Boston, MA-- Prostate cancer is the most common cancer among males in the United States. Approximately, 180,000 men are diagnosed each year, and approximately 95 percent of these men have localized disease that is potentially curable. Previously, studies have consistently demonstrated that conventionally fractionated high dose external beam radiation therapy (CRT), consisting of daily treatment for two months, decreases prostate cancer recurrence, and improves metastasis-free survival.

Three new articles present trends in survival for patients with ovarian, colon, and breast cancer in the United States by race and stage.

Close to half of transgender young Canadians aren't accessing health care when they need it, according to a new study from the University of British Columbia.

The study also found that increasing confidence in health-care providers is important for improving the physical and mental health of transgender youth.

It is estimated that between 14,000 and 15,000 Americans have amyotrophic lateral sclerosis (ALS), according to the National Institutes of Health. Symptoms of ALS, also known as Lou Gehrig's disease, may be subtle at first but develop into more obvious muscle weakness and paralysis. Recently, a University of Missouri researcher identified a potential target for therapeutics that may help to lessen the severity and progression of ALS. Researchers suggest that this same enzyme pathway also could help in the recovery of patients who have suffered strokes and other disorders.

LOS ANGELES (Dec. 4, 2017) -- When pharmacy professionals -- rather than doctors or nurses -- take medication histories of patients in emergency departments, mistakes in drug orders can be reduced by more than 80 percent, according to a study led by Cedars-Sinai.

Acting on the findings, Cedars-Sinai now assigns pharmacy staff members to take medication histories for high-risk patients admitted to the hospital through the Emergency Department.