Brain

(MEMPHIS, Tenn. - November 24, 2014) Most long-term survivors of retinoblastoma, particularly those who had been diagnosed with tumors by their first birthdays, have normal cognitive function as adults, according to a St. Jude Children's Research Hospital study. The research, which appears in the current issue of the journal Cancer, found that the vast majority of survivors work full time, live independently and fulfill other milestones of adult life.

Scientists have discovered a gene that protects people against one of the major causes of stroke in young and middle-aged adults and could hold the key to new treatments.

Researchers from Royal Holloway, University of London, together with an international team from across the United States and Europe, have found that people with a specific variant of a gene, known as PHACTR1, are at reduced risk of suffering cervical artery dissection, which is caused by a tear in an artery that leads to the brain.

After more than six years of intensive effort, and repeated failures that made the quest at times seem futile, Harvard Stem Cell Institute (HSCI) researchers at Boston Children's Hospital (BCH) and Harvard's Department of Stem Cell and Regenerative Biology (HSCRB) have successfully converted mouse and human skin cells into pain sensing neurons that respond to a number of stimuli that cause acute and inflammatory pain.

Beer-Sheva, Israel, Nov. 24, 2014 - A new, enhanced MRI diagnostic approach was, for the first time, able to identify significant damage to the blood-brain barrier (BBB) of professional football players following "unreported" trauma or mild concussions. Published in the current issue of JAMA Neurology, this study could improve decision making on when an athlete should "return to play."

"Memetics," or the study of memes, is a very popular discipline among cultural researchers now, particularly as it concerns new media like viral videos. But no one seems to know what a meme really is.

ANN ARBOR--The medical community may be inadvertently creating a new generation of illegal, recreational drug users by prescribing anti-anxiety or sleep medications to teenagers, say University of Michigan researchers.

Teens prescribed anxiety or sleep medications are up to 12 times more likely to abuse those drugs than those who had never had a prescription, either by using someone else's prescription pills or to get high or experiment, according to a study from the U-M School of Nursing.

A protein that stimulates the brain to awaken from sleep may be a target for preventing Alzheimer's disease, a study by researchers at Washington University School of Medicine in St. Louis suggests.

In recent years, scientists at Washington University have established links between sleep problems and Alzheimer's. For example, they have shown in people and in mice that sleep loss contributes to the growth of brain plaques characteristic of Alzheimer's, and increases the risk of dementia.

There has been a growing concern that modern society is increasingly lonely. In 2006, a New York Times article "The Lonely American Just Got a Bit Lonelier" highlighted research that shows a decline in social engagement--people are less likely to join clubs, have fewer close friends, and are less likely to perceive others as trustworthy. However, studies have also shown an increase in extraversion and self-esteem, which suggests loneliness is decreasing.

Abnormal connections between neurons are the likely cause of motor coordination issues seen in autism spectrum disorder. Using a mouse model of autism, scientists from the University of Chicago identified a malfunctioning neural circuit associated with reduced capacity for motor learning. This appears to arise from an inability to eliminate unneeded neural connections in the brain. They report their findings Nov. 24 in Nature Communications.

Adult survivors of retinoblastoma, a type of eye cancer that usually develops in early childhood, have few cognitive or social problems decades following their diagnosis and treatment. That's the conclusion of a study published early online in CANCER, a peer-reviewed journal of the American Cancer Society. The findings offer good news for patients, but it's important to continue to monitor for long-term effects as the brain changes throughout life.

A gene associated with schizophrenia plays a role in brain development and may help to explain the biological process of the disease, according to new Rutgers research.

In the study, published in Biological Psychiatry, Bonnie Firestein, professor in the Department of Cell Biology and Neuroscience, says too much protein expressed by the NOS1AP gene, which has been associated with schizophrenia, causes abnormalities in brain structure and faulty connections between nerve cells that prevent them from communicating properly.

Babies start breathing in the womb, inhaling and exhaling irregularly at first, and then gradually more and more, until the day when they're born and have to do it all the time. But premature babies sometimes have trouble. They stop breathing periodically, sometimes for 20 or 30 seconds at a time. Sometimes they're fine, and sometimes they're not, and doctors struggle to help them. That may soon change, however, thanks to a two-month-old patient at UConn Health with a rare connexin mutation, and his doctor's willingness to call for help.

Repeat suicide attempts and deaths by suicide were roughly 25 percent lower among a group of Danish people who underwent voluntary short-term psychosocial counseling after a suicide attempt, new Johns Hopkins Bloomberg School of Public Health-led research suggests.

An intervention that uses music and games to help preschoolers learn self-regulation skills is helping prepare at-risk children for kindergarten, a new study from Oregon State University shows.

Self-regulation skills - the skills that help children pay attention, follow directions, stay on task and persist through difficulty - are critical to a child's success in kindergarten and beyond, said OSU's Megan McClelland, a nationally recognized expert in child development and a co-author of the new study.

You're at a slumber party with your friends. One friend asks "if a guy at school asked you out, but you weren't really attracted to him, would you go?" You laugh and shake your head no: "Why would I, if he's not my type?"

Or imagine you're at school, sitting in the cafeteria. A guy who you think is attractive but who has some unsuitable personality traits comes up and asks you out. You say yes, even though what you really meant to say was no. "Why did I do that?" you wonder.