Brain

Pre-treatment scans of brain activity predicted whether depressed patients would best achieve remission with an antidepressant medication or psychotherapy, in a study funded by the National Institutes of Health.

"Our goal is to develop reliable biomarkers that match an individual patient to the treatment option most likely to be successful, while also avoiding those that will be ineffective," explained Helen Mayberg, M.D., of Emory University, Atlanta, a grantee of the NIH's National Institute of Mental Health.

Scientists at Washington University School of Medicine in St. Louis have measured a significant and potentially pivotal difference between the brains of patients with an inherited form of Alzheimer's disease and healthy family members who do not carry a mutation for the disease.

Researchers have known that amyloid beta, a protein fragment, builds up into plaques in the brains of Alzheimer's patients. They believe the plaques cause the memory loss and other cognitive problems that characterize the disease. Normal brain metabolism produces different forms of amyloid beta.

LA JOLLA, CA – June 12, 2013 – Scientists at The Scripps Research Institute (TSRI) have found evidence that an emotion-related brain region called the central amygdala—whose activity promotes feelings of malaise and unhappiness—plays a major role in sustaining cocaine addiction.

RIVERSIDE, Calif. — Performing experiments in a river in Trinidad, a team of evolutionary biologists has found that male guppies continue to reproduce for at least ten months after they die, living on as stored sperm in females, who have much longer lifespans (two years) than males (three-four months).

Multiple drug classes commonly prescribed for common medical conditions are capable of influencing the onset and progression of Alzheimer's disease, according to researchers at The Mount Sinai Medical Center. The findings are published online in the journal PLoS One.

Montreal, June 12, 2013 – From Brad Pitt fighting zombies to Superman falling for Lois Lane, summer blockbuster season is upon us. But while Hollywood keeps trotting out new movies for the masses, plotlines barely change.

Epic battles, whirlwind romances, family feuds, heroic attempts to save the lives of strangers: these are stories guaranteed to grace the silver screen. According to new research from Concordia University, that's not lazy scriptwriting, that's evolutionary consumerism.

Smile and the world smiles with you — but new research suggests that not all smiles are created equal. The research shows that people actually anticipate smiles that are genuine but not smiles that are merely polite. The differing responses may reflect the unique social value of genuine smiles.

PHILADELPHIA— Sperm doesn't appear to forget anything. Stress felt by dad—whether as a preadolescent or adult—leaves a lasting impression on his sperm that gives sons and daughters a blunted reaction to stress, a response linked to several mental disorders. The findings, published in a new preclinical study in the Journal of Neuroscience by researchers at the University of Pennsylvania, point to a never-before-seen epigenetic link to stress-related diseases such as anxiety and depression passed from father to child.

PITTSBURGH—Researchers at Carnegie Mellon University have developed a method for tracking the locations of multiple individuals in complex, indoor settings using a network of video cameras, creating something similar to the fictional Marauder's Map used by Harry Potter to track comings and goings at the Hogwarts School.

This news release is available in German.

SALT LAKE CITY, June 12, 2013 – Using hands-free devices to talk, text or send e-mail while driving is distracting and risky, contrary to what many people believe, says a new University of Utah study issued today by the AAA Foundation for Traffic Safety.

"Our research shows that hands-free is not risk-free," says University of Utah psychology Professor David Strayer, lead author of the study, which he conducted for the foundation arm of the nonprofit AAA, formerly known as the American Automobile Association.

A team of Johns Hopkins researchers working with animals has developed a vaccine that prevents the virulent TB bacterium from invading the brain and causing the highly lethal condition TB meningitis, a disease that disproportionately occurs in TB-infected children and in adults with compromised immune system.

A report on the federally funded research is published online June 11 in the journal PLOS ONE.

CHICAGO -– Fever-induced childhood seizures, known as febrile seizures, can be terrifying for parents to witness. The full-body convulsions, which mostly affect children six months to five years old, can last from mere seconds up to more than 40 minutes. Currently, children are not treated with daily anticonvulsant medication to prevent these seizures even when they recur repeatedly because toxic side effects of existing treatments outweigh potential benefits.

DURHAM, N.C. -- Hours spent at the video gaming console not only train a player's hands to work the buttons on the controller, they probably also train the brain to make better and faster use of visual input, according to Duke University researchers.

"Gamers see the world differently," said Greg Appelbaum, an assistant professor of psychiatry in the Duke School of Medicine. "They are able to extract more information from a visual scene."

Small electrodes placed on or inside the brain allow patients to interact with computers or control robotic limbs simply by thinking about how to execute those actions. This technology could improve communication and daily life for a person who is paralyzed or has lost the ability to speak from a stroke or neurodegenerative disease.