Brain

UCSB researchers identify the mechanisms underlying salt-mediated behaviors in fruit flies

(Santa Barbara, Calif.) — Next time you see a fruit fly in your kitchen, don't swat it. That fly could have a major impact on our progress in deciphering sensory biology and animal behavior, including someday providing a better understanding of the human brain.

Gustatory tug-of-war key to whether salty foods taste good

As anyone who's ever mixed up the sugar and salt while baking knows, too much of a good thing can be inedible. What hasn't been clear, though, is how our tongues and brains can tell when the saltiness of our food has crossed the line from yummy to yucky - or, worse, something dangerous.

GW researcher finds association between finasteride and decreased levels of alcohol consumption

WASHINGTON (June 11, 2013) —Researcher Michael S. Irwig, M.D., F.A.C.E., assistant professor of medicine at the George Washington University (GW) School of Medicine and Health Sciences (SMHS) and director of the Center for Andrology at The GW Medical Faculty Associates, found that men who used the medication finasteride (Propecia) and developed persistent sexual side effects, are also drinking less alcohol than before.

No good substitute for race in college admissions: Research

COLLEGE PARK, Md. – As the U.S. Supreme Court decides in a case involving racial preferences in higher education admissions (Fisher v. Texas), new University of Maryland-led research finds that socioeconomic diversity is no replacement for a direct consideration of race, as some have suggested. Still the research finds that a mix of students from differing socio-economic backgrounds has benefits.

Study points to role of nervous system in arthritis

Arthritis is a debilitating disorder affecting one in 10 Canadians, with pain caused by inflammation and damage to joints.

Yet the condition is poorly managed in most patients, since adequate treatments are lacking – and the therapies that do exist to ease arthritis pain often cause serious side effects, particularly when used long-term. Any hope for developing more-effective treatments for arthritis relies on understanding the processes driving this condition.

A peptide to protect brain function

A structure called "the microtubule network" is a crucial part of our nervous system. It acts as a transportation system within nerve cells, carrying essential proteins and enabling cell-to-cell communications. But in neurodegenerative diseases like Alzheimer's, ALS, and Parkinson's, this network breaks down, hindering motor abilities and cognitive function.

Helping to restore balance after inner ear disorder

Many disorders of the inner hear which affect both hearing and balance can be hugely debilitating and are currently largely incurable. Cochlear implants have been used for many years to replace lost hearing resulting from inner ear damage. However, to date, there has not been an analogous treatment for balance disorders resulting from inner ear disease. One potential new treatment is an implantable vestibular prosthesis which would directly activate the vestibular nerve by electrical stimulation.

Researchers gain new molecular-level understanding of the brain's recovery after stroke

DETROIT – A specific MicroRNA, a short set of RNA (ribonuclease) sequences, naturally packaged into minute (50 nanometers) lipid containers called exosomes, are released by stem cells after a stroke and contribute to better neurological recovery according to a new animal study by Henry Ford Hospital researchers.

UF study finds brain-imaging technique can help diagnose movement disorders

GAINESVILLE, Fla. — A new University of Florida study suggests a promising brain-imaging technique has the potential to improve diagnoses for the millions of people with movement disorders such as Parkinson's disease.

Utilizing the diffusion tensor imaging technique, as it is known, could allow clinicians to assess people earlier, leading to improved treatment interventions and therapies for patients.

Helmet crash tests: Don't hit the road without one

Sydney: A laboratory study has found that bicycle helmets certified to Australia's national standard significantly reduce the causes of head, skull and brain injury - linear and angular head accelerations, and the impact force of a crash.

Crashing without a helmet exposes the head to accelerations and forces – or loads - up to 9.5 times greater than with a helmet and so greatly increases the risk of head, skull and brain injury, according to a detailed biomechanical study published in the journal Traffic Injury Prevention.

Volunteering reduces risk of hypertension in older adults, Carnegie Mellon research shows

PITTSBURGH—It turns out that helping others can also help you protect yourself from high blood pressure.

Sleep mechanism identified that plays role in emotional memory

RIVERSIDE, Calif. — Sleep researchers from University of California campuses in Riverside and San Diego have identified the sleep mechanism that enables the brain to consolidate emotional memory and found that a popular prescription sleep aid heightens the recollection of and response to negative memories.

Their findings have implications for individuals suffering from insomnia related to posttraumatic stress disorder (PTSD) and other anxiety disorders who are prescribed zolpidem (Ambien) to help them sleep.

Doubling of deaths among sick mums-to-be amid poor evidence on drug safety in pregnancy

The lack of hard data on the safety and effectiveness of a wide range of drugs in pregnancy has hindered the treatment of pregnant women, contributing to a doubling of deaths amongst mums-to-be with an underlying health problem over the past 20 years, argues an editorial in the Drug and Therapeutics Bulletin (DTB).

It's time to include pregnant women in drug trials so that they can get the medical treatment they need, says DTB.

Biomarkers may be key to discovery of successful initial treatment of depression

In a National Institutes of Health (NIH) funded clinical trial, researchers at Emory have discovered that specific patterns of brain activity may indicate whether a depressed patient will or will not respond to treatment with medication or psychotherapy. The study was published June 12, 2013, in JAMA Psychiatry Online First.

The choice of medication versus psychotherapy is often based on the preference of the patient or clinician, rather than objective factors. On average, 35-40 percent of patients get well with whatever treatment they start with.

New imaging technique holds promise for speeding MS research

Researchers at the University of British Columbia have developed a new magnetic resonance imaging (MRI) technique that detects the telltale signs of multiple sclerosis in finer detail than ever before – providing a more powerful tool for evaluating new treatments.