Brain

Stress wrecks intestinal bacteria, could keep immune system on idle

COLUMBUS, Ohio – Stress not only sends the human immune system into overdrive – it can also wreak havoc on the trillions of bacteria that work and thrive inside our digestive system.

New research suggests that this may be important because those bacteria play a significant role in triggering the innate immune system to stay slightly active, and thereby prepared to quickly spring into action in the face of an infection.

But exactly how stress makes these changes in these bacteria still isn't quite clear, researchers say.

Periodontal stem cell transplantation shows promise

Tampa, Fla. (April 11, 2011) – Periodontal ligament stem cells (PDLSCs) have been found to be the most efficacious of three kinds of clinically tested dental tissue-derived stem cells, reports a study published in the current issue of Cell Transplantation (20:2), freely available on-line at http://www.ingentaconnect.com/content/cog/ct/.

Umbilical cord blood-derived stem cells studied for lupus therapy

Tampa, Fla. (April 11, 2011) – Human umbilical cord blood-derived mensenchymal stem cells (uMSCs) have been found to offer benefits for treating lupus nephritis (LN) when transplanted into mouse models of systemic lupus erythematosus (SLE). SLE is an autoimmune disease with "myriad immune system aberrations" characterized by diverse clinical conditions, including LN, a leading cause of morbidity and mortality for patients with SLE.

In it to win it?

Pathological gambling addiction is surprisingly common in the U.S., afflicting as many as 3.4% of all adults. Like other addictions, it is highly disabling both to the individual and to society, often leading to suicide, job loss, and criminal behavior. It affects more men than women and can become worse over time.

Scientists find potential benefit of hypericin for recurrent brain tumors

SALT LAKE CITY – Researchers have found that a synthetic version of hypericin, a compound naturally found in St. John's wort, may be a promising treatment for patients with recurrent malignant brain tumors. Their findings were published online on March 31, 2011 in the journal Cancer.

Sleep issues contribute to cognitive problems in childhood cancer survivors

A new analysis has found that childhood cancer survivors often suffer from sleep problems and fatigue, which negatively impact their attention and memory. Published early online in Cancer, a peer-reviewed journal of the American Cancer Society, the study indicates that addressing sleep hygiene among survivors of childhood cancer may help to improve their cognitive health.

Flu helps spread pneumonia

Bacteria that cause pneumonia and meningitis are only able to spread when individuals are infected with flu, says a scientist reporting at the Society for General Microbiology's Spring Conference in Harrogate. The work could have implications for the management of influenza pandemics and could help reduce incidence of pneumococcal infections in very young children, who are more susceptible to disease.

Experimental drug achieves unprecedented weight loss

DURHAM, N.C.— An investigational combination of drugs already approved to treat obesity, migraine and epilepsy produced up to a 10 percent weight loss in obese individuals participating in a one-year clinical trial, according to researchers at Duke University Medical Center.

Mapping the brain: New technique poised to untangle the complexity of the brain

Scientists have moved a step closer to being able to develop a computer model of the brain after developing a technique to map both the connections and functions of nerve cells in the brain together for the first time.

Surveys confirm enormous value of science museums, 'free choice' learning

CORVALLIS, Ore. – One of the first studies of its type has confirmed that a science museum can strongly influence the public's knowledge and attitudes about science and technology, and to a surprising degree can cut across racial, ethnic, educational and economic barriers.

NYU Langone experts present advances at American Association of Neurological Surgeons Meeting

Neurosurgeons from NYU Langone Medical Center will present techniques and discuss surgical approaches and applications of technology at the annual meeting of the American Association of Neurological Surgeons (AANS), held April 9-13, 2011 at the Colorado Convention Center in Denver.

Dopamine controls formation of new brain cells

A study of the salamander brain has led researchers at the Swedish medical university Karolinska Institutet to discover a hitherto unknown function of the neurotransmitter dopamine. In an article published in the prestigious scientific journal Cell Stem Cell they show how in acting as a kind of switch for stem cells, dopamine controls the formation of new neurons in the adult brain. Their findings may one day contribute to new treatments for neurodegenerative diseases, such as Parkinson's.

Late diagnosis is major factor in hospital cancer deaths

Late cancer diagnosis in Northern Ireland contributes to hospital deaths despite patient's preference to die at home according to a major report launched at Queen's University Belfast.

The study conducted by the Northern Ireland Cancer Registry and funded by the Ulster Cancer Foundation found that while patients who die in hospital with cancer are very ill, late diagnosis of their cancer is a major factor in hospital cancer deaths here. This is the first ever study in Northern Ireland specifically investigating why cancer patients die in acute hospitals.

People control thoughts better when they see their brain activity: UBC study

As humans face increasing distractions in their personal and professional lives, University of British Columbia researchers have discovered that people can gain greater control over their thoughts with real-time brain feedback.

New model of whiskers provides insight into sense of touch

Researchers at Northwestern University have developed a model that will allow them to simulate how rats use their whiskers to sense objects around them. The model enables further research that may provide insight into the human sense of touch.