Brain

Timing is crucial for family consent in brain dead organ donors

Hearts used in transplants can only be sourced from donors that are brain dead before circulation to their heart has ceased. Data from a study published in BioMed Central's open access journal Critical Care indicate that the time at which organ donation in brain dead donors is first discussed with family members could affect whether or not they consent to donation.

The researchers believe that discussing the issue of donation with relatives of victims of catastrophic brain injury earlier on in the process may have a negative effect on the consent rate.

Distinct AIDS viruses found in cerebrospinal fluid of people with HIV dementia

CHAPEL HILL, N.C. -- When the virus that causes AIDS infects the central nervous system, it can lead to the development of a severe neurological disease called HIV-associated dementia (HAD).

The advent of highly active antiretroviral therapy, or HAART, has helped reduce HAD. But some studies show that HAART may not offer complete protection from less severe HIV-associated neurological problems, nor might it always help to reverse it. As people live longer with AIDS, their risk of developing neurological problems may increase.

Mine-hunting software helping doctors to identify rare cells in human cancer

ARLINGTON, Va. -- Medical researchers are demonstrating that Office of Naval Research (ONR)-funded software developed for finding and recognizing undersea mines can help doctors identify and classify cancer-related cells.

"The results are spectacular," said Dr. Larry Carin, professor at Duke University and developer of the technology. "This could be a game changer for medical research."

The problem that physicians encounter in analyzing images of human cells is surprisingly similar to the Navy's challenge of finding undersea mines.

Changes in brain function in early HIV infection: A reliable indicator of disease prognosis?

New Rochelle, NY, October 6, 2011—Measurable changes in brain function and communication between brain regions may be a consequence of virus-induced injury during the early stages of human immunodeficiency virus (HIV) infection. These abnormalities and their implications in disease prognosis are detailed in an article in the groundbreaking new neuroscience journal Brain Connectivity, a bimonthly peer-reviewed journal published by Mary Ann Liebert, Inc.

Scripps Research scientists find stem cell reprogramming technique is safer than previously thought

LA JOLLA, CA – October 6, 2011 — Stem cells made by reprogramming patients' own cells might one day be used as therapies for a host of diseases, but scientists have feared that dangerous mutations within these cells might be caused by current reprogramming techniques. A sophisticated new analysis of stem cells' DNA finds that such fears may be unwarranted.

Expression of pluripotency-associated gene marks many types of adult stem cells

Investigators at the Massachusetts General Hospital (MGH) Center for Regenerative Medicine and the Harvard Stem Cell Institute (HSCI) have found that Sox2 – one of the transcription factors used in the conversion of adult stem cells into induced pluripotent stem cells (iPSCs) – is expressed in many adult tissues where it had not been previously observed. They also confirmed that Sox2-expressing cells found in the stomach, testes, cervix and other structures are true adult stem cells that can give rise to all mature cell types in those tissues.

Ownership: Children believe human-made objects can be owned but not natural ones

WASHINGTON – Children as young as 3 are likely to say that things made by humans have owners, but that natural objects, such as pine cones and sea shells, are not owned, according to a new study published by the American Psychological Association.

Liberal or conservative? What the public expects to see in a candidate's face

Scientists have uncovered specific facial characteristics which make MPs look like they belong to one of the two major political parties in Britain.

Labour MPs have broader smiles, dimples and a rounder, softer face than their Conservative counterparts, according to research from Queen Mary, University of London and UCL (University College London) published this week.

Detecting glaucoma before it blinds

Early detection and diagnosis of open angle glaucoma important so that treatment can be used in the early stages of the disease developing to prevent or avoid further vision loss. Writing in a forthcoming issue of the International Journal of Medical Engineering and Informatics, researchers in the US have analyzed and ranked the various risk factors for open angle glaucoma so that patients can be screened at an earlier stage if they are more likely to develop the condition.

How fair sanctions are orchestrated in the brain

Civilized human cohabitation requires us to respect elementary social norms. We guarantee compliance with these norms with our willingness to punish norm violations – often even at our own expense. This behavior goes against our own economic self-interest and requires us to control our egoistic impulses.

Innovative combination of methods

Athletes: Winning streaks may not be all in their heads

When an athlete consistently does well, sports commentators may describe them as being "hot" or "on fire." Scientists have debunked these streaks as being in the eye of the beholder, but a new study by Yale School of Medicine researchers supports the "hot hand" phenomenon: that a streak of positive outcomes is likely to continue.

Illusory memories can have salutary effects

"False memories tend to get a bad rap," says developmental psychologist Mark L. Howe, of Lancaster University in England. Indeed, remembering events incorrectly or remembering events that didn't happen can have grave consequences, such as the criminal conviction of an innocent person. "But false memories are a natural outcropping of memory in general. They must have some positive effect, too."

Virginia Commonwealth University study: We are what we experience

Our life experiences -- the ups and downs, and everything in between -- shape us, stay with us and influence our emotional set point as adults, according to a new study led by Virginia Commonwealth University researchers.

The study suggests that, in addition to our genes, our life experiences are important influences on our levels of anxiety and depression.

Monkeys 'move and feel' virtual objects using only their brains

DURHAM, N.C.-- In a first ever demonstration of a two-way interaction between a primate brain and a virtual body, two monkeys trained at the Duke University Center for Neuroengineering learned to employ brain activity alone to move an avatar hand and identify the texture of virtual objects.

New mouse model recreates common form of autism

BOSTON –Over the past decade, new technologies have revealed that autism spectrum disorder has a substantial genetic component. But determining exactly which genes are involved has been like finding the proverbial needle in the haystack.