Serotonin, a neurotransmitter in the brain, shortens periods of apnoea (temporary cessation of breathing) and promotes inspiration, according to a study published today in Experimental Physiology.
The researchers found that when injected into a specific part of the brain (the brain stem) serotonin shortens apnoeic events by interacting with a specific serotonin receptor, the 5-HT3 receptor, which, in healthy babies, is highly expressed in a region of the brainstem associated with the control of apnoeas and regular breathing.