Brain

Philadelphia, PA, April 2, 2012 – Testosterone, the primary male sex hormone, appears to have antidepressant properties, but the exact mechanisms underlying its effects have remained unclear. Nicole Carrier and Mohamed Kabbaj, scientists at Florida State University, are actively working to elucidate these mechanisms.

They've discovered that a specific pathway in the hippocampus, a brain region involved in memory formation and regulation of stress responses, plays a major role in mediating testosterone's effects, according to their new report in Biological Psychiatry.

Sleep plays a powerful role in preserving our memories. But while recent research shows that wakefulness may cloud memories of negative or traumatic events, a new study has found that wakefulness also degrades positive memories. Sleep, it seems, protects positive memories just as it does negative ones, and that has important implications for the treatment of post-traumatic stress disorder.

New research suggests that when non-religious people think about their own death they become more consciously skeptical about religion, but unconsciously grow more receptive to religious belief.

The research, from the Department of Psychology at the University of Otago in New Zealand, also found that when religious people think about death, their religious beliefs appear to strengthen at both conscious and unconscious levels. The researchers believe the findings help explain why religion is such a durable feature of human society.

New research confirms that childhood onset temporal lobe epilepsy has a significant impact on brain aging. Study findings published in Epilepsia, a peer-reviewed journal of the International League Against Epilepsy (ILAE), show age-accelerated ventricular expansion outside the normal range in this patient population.

Why do some persons succumb to post-traumatic stress disorder (PTSD) while others who suffered the same ordeal do not? A new UCLA study may shed light on the answer.

UCLA scientists have linked two genes involved in serotonin production to a higher risk of developing PTSD. Published in the April 3 online edition of the Journal of Affective Disorders, the findings suggest that susceptibility to PTSD is inherited, pointing to new ways of screening for and treating the disorder.

Rutgers scientists think they have found a way to prevent and possibly reverse the most debilitating symptoms of a rare, progressive childhood degenerative disease that leaves children with slurred speech, unable to walk, and in a wheelchair before they reach adolescence.

The deposition of amyloid beta in the brain of individuals with Alzheimer's disease is the focus of much research into both its cause and treatment.

While there may not be a consensus as to whether the deposition contributes to the disease or is a consequence of the disease, there is agreement that it is not favoured thermodynamically, meaning that something else is promoting the process.

Scientists have taken an important step forward in developing a new material using nano-sized magnets that could ultimately lead to new types of electronic devices, with greater capacity than is currently feasible, in a study published today in the journal Science.

Many modern data storage devices, like hard disk drives, rely on the ability to manipulate the properties of tiny individual magnetic sections, but their overall design is limited by the way these magnetic 'domains' interact when they are close together.

WASHINGTON — An estimated 2.2 million people in the United States live with epilepsy, a complex brain disorder characterized by sudden and often unpredictable seizures. The highest rate of onset occurs in children and older adults, and it affects people of all ethnicities and socio-economic backgrounds, yet this common disorder is widely misunderstood. Epilepsy refers to a spectrum of disorders with seizures that vary in type, cause, severity, and frequency. Many people do not know the causes of epilepsy or what measures to take if they witness a seizure.

What experts and the public have already long suspected is now supported by representative data collected by researchers at Ruhr-Universität Bochum (RUB) and University of Basel: ADHD, attention deficit hyperactivity disorder, is over-diagnosed. The study showed that child and adolescent psychotherapists and psychiatrists tend to give a diagnosis based on heuristics, unclear rules of thumb, rather than adhering to recognized diagnostic criteria. Boys in particular are substantially more often misdiagnosed compared to girls. These are the most important results of a study conducted by Prof.

PITTSBURGH—Sooner than later, robots may have the ability to "feel." In a paper published online March 26 in Advanced Functional Materials, a team of researchers from the University of Pittsburgh and the Massachusetts Institute of Technology (MIT) demonstrated that a nonoscillating gel can be resuscitated in a fashion similar to a medical cardiopulmonary resuscitation. These findings pave the way for the development of a wide range of new applications that sense mechanical stimuli and respond chemically—a natural phenomenon few materials have been able to mimic.

DURHAM, N.C. -- People who have experienced a stroke or transient ischemic attack (TIA) experience high rates of depression, but up to two-thirds of them are undertreated, according to new findings from Duke University Medical Center.

Daniel Laskowitz, M.D., a professor of medicine at Duke and the senior author of the study published today in the American Heart Association journal Stroke, called the findings "striking."

Greater lifetime exposure to the stress of traumatic events was linked to higher levels of inflammation in a study of almost 1,000 patients with cardiovascular disease led by researchers at the San Francisco VA Medical Center and the University of California, San Francisco.

The brain appears to be wired more like the checkerboard streets of New York City than the curvy lanes of Columbia, Md., suggests a new brain imaging study. The most detailed images, to date, reveal a pervasive 3D grid structure with no diagonals, say scientists funded by the National Institutes of Health.

How do you build a brain? In the March 30 issue of Science a team of investigators presents a surprising answer, reporting their discovery of a remarkably simple organizational structure in the brains of humans and other primates. Employing sophisticated mathematical analysis of advanced imaging data, they found that the pathways carrying neural signals through the brain are arranged not in a disorganized tangle but in a curved, three-dimensional grid.