Brain

Research from Karolinska Institutet in Sweden shows that the human olfactory bulb – a structure in the brain that processes sensory input from the nose – differs from that of other mammals in that no new neurons are formed in this area after birth. The discovery, which is published in the scientific journal Neuron, is based on the age-determination of the cells using the carbon-14 method, and might explain why the human sense of smell is normally much worse than that of other animals.

(SACRAMENTO, Calif.) — A team of UC Davis researchers has found thatmothers who had fevers during their pregnancies were more than twice aslikely to have a child with autism or developmental delay than weremothers who did not have a fever or who took medication to counter itseffect.

Biologists at UC San Diego have discovered that a small dose of a commonly used crop pesticide turns honey bees into "picky eaters" and affects their ability to recruit their nestmates to otherwise good sources of food.

The results of their experiments, detailed in this week's issue of the Journal of Experimental Biology, have implications for what pesticides should be applied to bee-pollinated crops and shed light on one of the main culprits suspected to be behind the recent declines in honey bee colonies.

A new psychological intervention has been shown to more than halve the trauma experienced by child victims of war, rape and sexual abuse.

Researchers at Queen's University Belfast pioneered the intervention in conjunction with the international NGO, World Vision as part of a wider programme to treat psychological distress in child victims of war and sexual violence in the Democratic Republic of Congo (DRC).

Long before babies understand the story of Goldilocks, they have more than mastered the fairy tale heroine's method of decision-making. Infants ignore information that is too simple or too complex, focusing instead on situations that are "just right," according to a new study to be published in the journal PLoS ONE on May 23.

(SACRAMENTO, Calif.) — A team of UC Davis researchers has found that mothers who had fevers during their pregnancies were more than twice as likely to have a child with autism or developmental delay than were mothers of typically developing children, and that taking medication to treat fever countered its effect.

A novel anti-inflammatory drug could help to improve survival in the most severe cases of malaria by preventing the immune system from causing irrevocable brain and tissue damage.

Walter and Eliza Hall Institute researchers have shown that a new class of anti-inflammatory agents, called IDR (innate defense regulator) peptides, could help to increase survival from severe clinical malaria when used in combination with antimalarial drugs.

Researchers at New York University and Albert Einstein College of Medicine of Yeshiva University have discovered new ways neurons work together to ease the transition between sleep and wakefulness. Their findings, which appear in the journal Neuron, provide additional insights into sleep-wake patterns and offer methods to explore what may disrupt them.

A new study finds that transplanting embryonic cells into adult mouse spinal cord can alleviate persistent pain. The research, published by Cell Press in the May 24th issue of the journal Neuron, suggests that reduced pain results from successful integration of the embryonic cells into the host spinal cord. The findings open avenues for clinical strategies aimed not just at treating the symptoms of chronic debilitating pain, but correcting the underlying disease pathology.

A new study unravels a link between a protein that can modify cellular metabolism in the brain and seizure susceptibility. The research, published by Cell Press in the May 24th issue of the journal Neuron, may lead to the development of new treatments for epilepsy.

For decades, neurologists have known that a diet high in fat and extremely low in carbohydrates can reduce epileptic seizures that resist drug therapy. But how the diet worked, and why, was a mystery—so much so that in 2010, The New York Times Magazine called it "Epilepsy's Big, Fat Miracle."

Researchers have shown in mice how immune cells in the brain target and remove unused connections between brain cells during normal development. This research, supported by the National Institutes of Health, sheds light on how brain activity influences brain development, and highlights the newly found importance of the immune system in how the brain is wired, as well as how the brain forms new connections throughout life in response to change.

What do employees think of their boss when he or she makes a mistake? According to a new study, leaders who make mistakes are seen as less competent, less desirable to work for and less effective than leaders who do not. And if the leader is a man making a mistake in a man's world, he is judged more harshly than a woman making the same mistake in a man's world. The work by Christian Thoroughgood, from the Pennsylvania State University in the US, and his colleagues, is published online in Springer's Journal of Business and Psychology.

When confronted with adverse situations such as the loss of a loved one, some people never fully recover from the pain. Others, the majority, pull through and experiment how the intensity of negative emotions (e.g. anxiety, depression) grows dimmer with time until they adapt to the new situation. A third group is made up of individuals whose adversities have made them grow personally and whose life takes on new meaning, making them feel stronger than before.

Use of the antioxidant urate to protect against the neurodegeneration caused by Parkinson's disease appears to rely on more than urate's ability to protect against oxidative damage. In the May issue of the open-access journal PLoS One, researchers from the MassGeneral Institute for Neurodegenerative Diseases (MGH-MIND) describe experiments suggesting the involvement of a novel mechanism in urate's protection of cultured brain cells against Parkinson's-like damage.