Brain

Measuring metabolism can predict Alzheimer's progress with 90 percent accuracy

When it comes to Alzheimer's disease, scientists usually — and understandably — look to the brain as their first center of attention. Now researchers at Tel Aviv University say that early clues regarding the progression of the disease can be found in the brain's metabolism.

Stem cells + nanofibers = Promising nerve research

ANN ARBOR, Mich. — Every week in his clinic at the University of Michigan, neurologist Joseph Corey, M.D., Ph.D., treats patients whose nerves are dying or shrinking due to disease or injury.

He sees the pain, the loss of ability and the other effects that nerve-destroying conditions cause – and wishes he could give patients more effective treatments than what's available, or regenerate their nerves. Then he heads to his research lab at the VA Ann Arbor Healthcare System, where his team is working toward that exact goal.

Self-imagination can enhance memory in healthy and memory-impaired individuals

There's no question that our ability to remember informs our sense of self. Now research published in Clinical Psychological Science, a journal of the Association for Psychological Science, provides new evidence that the relationship may also work the other way around: Invoking our sense of self can influence what we are able to remember.

New cell type developed for possible treatment of Alzheimer's and other brain diseases

Irvine, Calif., Nov. 7, 2012 — UC Irvine researchers have created a new stem cell-derived cell type with unique promise for treating neurodegenerative diseases such as Alzheimer's.

Dr. Edwin Monuki of UCI's Sue & Bill Gross Stem Cell Research Center, developmental & cell biology graduate student Momoko Watanabe and colleagues developed these cells –called choroid plexus epithelial cells – from existing mouse and human embryonic stem cell lines.

New insight into why haste makes waste

Why do our brains make more mistakes when we act quickly?A new study demonstrates how the brain follows Ben Franklin's famous dictum, "Take time for all things: great haste makes great waste."

The research – conducted by Research Assistant Professor Richard Heitz and Jeffrey Schall, Ingram Professor of Neuroscience, at Vanderbilt University – has found that the brain actually switches into a special mode when pushed to make rapid decisions.

The study was published Nov. 7 in the journal Neuron.

Teaching the blind to read and recognize objects with sounds

This is an example of one image from each of the visual categories used in the structured SSD training (geometric shapes, Hebrew letters, textures, body postures, everyday objects, houses, and faces) is demonstrated, along with its corresponding transformation to sound via the vOICe SSD (two repetitions of each 2-s-long soundscape).

(Photo Credit: Striem-Amit et al., Neuron)

Activating the 'mind's eye' -- sounds, instead of eyesight can be alternative vision

Jerusalem, Nov. 7, 2012 -- Common wisdom has it that if the visual cortex in the brain is deprived of visual information in early infanthood, it may never develop properly its functional specialization, making sight restoration later in life almost impossible.

Scientists at the Hebrew University of Jerusalem and in France have now shown that blind people – using specialized photographic and sound equipment – can actually "see" and describe objects and even identify letters and words.

Persistent sync for neurons

A team of Brazilian physicists working with neuroscientists studying freely behaving rats have found that their neurons often act in precise coordination over time, in a study about to be published in EPJ B. These findings stem from the work of Bruno Silva, a researcher at Bahia Federal University in Salvador, and his colleagues from other universities in the Northeastern region of Brazil, and suggest that neuronal networks' memory could be explored in the future.

Looking for the anti-Alzheimer's molecule -- A new approach to treating a devastating disease

Ottawa, Canada (November 7, 2012) – Researchers at Dalhousie University have discovered a new technique using "computer-aided" drug design that may lead to an entirely new approach in the treatment of Alzheimer's disease (AD).

Early treatment sparks striking brain changes in autism

When given early treatment, children with autism spectrum disorders (ASD) made significant improvements in behavior, communication, and most strikingly, brain function, Yale School of Medicine researchers report in a new study.

The study was published in the current issue of the Journal of Autism and Developmental Disorders by Yale Child Study Center researchers Fred Volkmar, M.D., Kevin A. Pelphrey, and their colleagues.

Clever cockatoo with skilled craftmanship

For the researchers it came as a surprise that Figaro used a tool at all, and more so, that the he made it by himself. The most important observation was that the cockatoo, after having managed to fashion his first tool, knew what to do without hesitation in further experiments. "Figaro made a new tool for every nut we placed there and each time the bird was successful in obtaining it", reports the cognitive biologist. Goffin's cockatoos are highly explorative known to be good problem solvers in technical areas, and large-brained.

A new development in the relief of spasms related to amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease with an occurrence rate in France similar to multiple sclerosis (two to three new cases per year for every 100,000 residents). It has a specific affect on neurons responsible for motor control, in particular motor neurones and central motor neurones. The former, located in the spinal cord, are directly linked to muscles and are used for muscle contraction and stretching. The latter, located in the brain, receive movement orders.

Pressure switch inside the head

To this day it remains a mystery why the cerebral pressure in certain people suddenly increases. The consequences, however, are better understood: The blood circulation is disrupted and after a while parts of the brain may die off, similar to what occurs in a stroke. This is how dementia takes its insidious path. Experts estimate that up to ten percent of all cases of dementia in Europe can be attributed to rising blood pressure in the brain. Still, making the diagnosis is tough.

Is your memory playing tricks on you? Check your medicine cabinet!

Duke Medicine News -- PTSD linked to smaller brain area regulating fear response

DURHAM, N.C. – Recent combat veterans who are diagnosed with post traumatic stress disorder have significantly smaller volume in an area of the brain critical for regulating fear and anxiety responses, according to research led by scientists at Duke University and the Durham VA Medical Center.