Brain

Mouse research links adolescent stress and severe adult mental illness

Working with mice, Johns Hopkins researchers have established a link between elevated levels of a stress hormone in adolescence — a critical time for brain development — and genetic changes that, in young adulthood, cause severe mental illness in those predisposed to it.

The findings, reported in the journal Science, could have wide-reaching implications in both the prevention and treatment of schizophrenia, severe depression and other mental illnesses.

Compensation negotiation among women in the workplace

Los Angeles, CA (January 15, 2012)- Studies have shown that women are less likely to take the most direct approach to ensure that they receive fair pay compared to their male counterparts – simply asking. So what happens when women begin to negotiate for higher salaries? Could women begin to close the gender pay gap simply by learning to negotiate for more money?

Implicit race bias increases the differences in the neural representations of black and white faces

Racial stereotypes have been shown to have subtle and unintended consequences on how we treat members of different race groups. According to new research published in Psychological Science, a journal of the Association for Psychological Science, race bias also increases differences in the brain's representations of faces.

New insights into the 'borderline personality' brain

New work by University of Toronto Scarborough researchers gives the best description yet of the neural circuits that underlie a severe mental illness called Borderline Personality Disorder (BPD), and could lead to better treatments and diagnosis.

The work shows that brain regions that process negative emotions (for example, anger and sadness) are overactive in people with BPD, while brain regions that would normally help damp down negative emotions are underactive.

Lack of key enzyme in the metabolism of folic acid leads to birth defects

AUSTIN, Texas — Researchers at The University of Texas at Austin have discovered that the lack of a critical enzyme in the folic acid metabolic pathway leads to neural tube birth defects in developing embryos.

It has been known for several decades that folic acid supplementation dramatically reduces the incidence of neural tube defects, such as spina bifida and anencephaly, which are among the most common birth defects. In some populations, folic acid supplementation has decreased neural tube defects by as much as 70 percent.

'Jet-lagged' fruit flies provide clues for body clock synchronisation

New research led by a team at Queen Mary, University of London, has found evidence of how daily changes in temperature affect the fruit fly's internal clock.

"A wide range of organisms, including insects and humans, have evolved an internal clock to regulate daily patterns of behaviour, such as sleep, appetite, and attention," explains Professor Ralf Stanewsky, senior study author from Queen Mary's School of Biological and Chemical Sciences.

Is athleticism linked to brain size?

The researchers found that compared to regular mice, those mice that had been selectively bred for high voluntary wheel-running had significantly greater midbrain volume as well as larger non-cerebellar brain mass, but not larger cerebella or total brain mass.

People with low risk for cocaine dependence have differently shaped brain to those with addiction

People who take cocaine over many years without becoming addicted have a brain structure which is significantly different from those individuals who developed cocaine-dependence, researchers have discovered. New research from the University of Cambridge has found that recreational drug users who have not developed a dependence have an abnormally large frontal lobe, the section of the brain implicated in self-control. Their research was published in the journal Biological Psychiatry.

New research finds slower growth of preterm infants linked to altered brain development

Preterm infants who grow more slowly as they approached what would have been their due dates also have slower development in an area of the brain called the cerebral cortex, report Canadian researchers in a new study published today in Science Translational Medicine.

The cerebral cortex is a two to four millimetre layer of cells that envelopes the top part of the brain and is involved in cognitive, behavioural, and motor processes.

Mindfulness meditation may relieve chronic inflammation

MADISON — People suffering from chronic inflammatory conditions, such as rheumatoid arthritis, inflammatory bowel disease and asthma — in which psychological stress plays a major role — may benefit from mindfulness meditation techniques, according to a study by University of Wisconsin-Madison neuroscientists with the Center for Investigating Healthy Minds at the Waisman Center.

NFL players may be at higher risk for depression as they age

SAN DIEGO – National Football League (NFL) players may be at increased risk of depression as they age due to brain damage resulting from concussions, according to two studies released today that will be presented at the American Academy of Neurology's 65th Annual Meeting in San Diego, March 16 to 23, 2013.

Popping the question is his job

Would women rather "pop the question?"

Apparently not. With marriage proposals in the air around the new year, researchers at UC Santa Cruz report that both women and men tend to hold traditional views when it comes to marriage proposals.

Young adults were asked about their personal preferences for marriage traditions. Overwhelmingly, both men and women said they would want the man in a relationship to propose marriage. A substantial majority of women also responded that they would want to take their husband's last name.

Scanning the brain: Scientists examine the impact of fMRI over the past 20 years

Understanding the human brain is one of the greatest scientific quests of all time, but the available methods have been very limited until recently. The development of functional magnetic resonance imaging (fMRI) — a tool used to gauge real-time brain activity by measuring changes in blood flow — opened up an exciting new landscape for exploration.

New biomarker may help in detecting gliomas, reports Neurosurgery

Philadelphia, Pa. (January 16, 2013) – Researchers using sophisticated genetic testing techniques have identified a promising new biomarker for diagnosis of glioma—the most common type of malignant brain tumor, reports the January issue of Neurosurgery, official journal of the Congress of Neurological Surgeons.

Promising new finding for therapies to treat persistent seizures in epileptic patients

LOS ANGELES (Jan. 16, 2013) – In a promising finding for epileptic patients suffering from persistent seizures known as status epilepticus, researchers reported today that new medication could help halt these devastating seizures. To do so, it would have to work directly to antagonize NMDA receptors, the predominant molecular device for controlling synaptic activity and memory function in the brain.