Brain

Dietary flavanols reverse age-related memory decline

NEW YORK, NY (October 26, 2014)—Dietary cocoa flavanols—naturally occurring bioactives found in cocoa—reversed age-related memory decline in healthy older adults, according to a study led by Columbia University Medical Center (CUMC) scientists. The study, published today in the advance online issue of Nature Neuroscience, provides the first direct evidence that one component of age-related memory decline in humans is caused by changes in a specific region of the brain and that this form of memory decline can be improved by a dietary intervention.

Activity in dendrites is critical in memory formation

Why do we remember some things and not others? In a unique imaging study, two Northwestern University researchers have discovered how neurons in the brain might allow some experiences to be remembered while others are forgotten. It turns out, if you want to remember something about your environment, you better involve your dendrites.

Heart drug may help treat ALS, mouse study shows

Digoxin, a medication used in the treatment of heart failure, may be adaptable for the treatment of amyotrophic lateral sclerosis (ALS), a progressive, paralyzing disease, suggests new research at Washington University School of Medicine in St. Louis.

ALS, also known as Lou Gehrig's disease, destroys the nerve cells that control muscles. This leads to loss of mobility, difficulty breathing and swallowing and eventually death. Riluzole, the sole medication approved to treat the disease, has only marginal benefits in patients.

Relationships benefit when parents and adult children use multiple communication channels

LAWRENCE – 'Call your mother' may be the familiar refrain, but research from the University of Kansas shows that being able to text, email and Facebook dad may be just as important for young adults.

Jennifer Schon, a doctoral student in communication studies, found that adult children's relationship satisfaction with their parents is modestly influenced by the number of communication tools, such as cell phones, email, social networking sites, they use to communicate.

Scientists engineer toxin-secreting stem cells to treat brain tumors

Harvard Stem Cell Institute scientists at Massachusetts General Hospital have devised a new way to use stem cells in the fight against brain cancer. A team led by neuroscientist Khalid Shah, MS, PhD, who recently demonstrated the value of stem cells loaded with cancer-killing herpes viruses, now has a way to genetically engineer stem cells so that they can produce and secrete tumor-killing toxins.

Intervention program helps prevent high-school dropouts

Tempe, Ariz. (Oct. 23, 2014) - New research findings from a team of prevention scientists at Arizona State University demonstrates that a family-focused intervention program for middle-school Mexican American children leads to fewer drop-out rates and lower rates of alcohol and illegal drug use.

"This is the first randomized prevention trial that we're aware of to show effects on school dropout for this population," said Nancy Gonzales, Foundation Professor in the REACH Institute and Psychology Department, College of Liberal Arts and Sciences at Arizona State University.

Medical costs for stroke survivors stay high 10 years on

New data shows that healthcare and personal costs to support survivors of stroke remains high 10 years on.

The Monash University research, published today in the journal Stroke, is the first to look at the long-term costs for the two main causes of stroke; ischemic where the blood supply stops due to a blood clot, and hemorrhagic, which occurs when a weakened blood vessel supplying the brain bursts.

Receiving gossip about others promotes self-reflection and growth

Gossip is pervasive in our society, and our penchant for gossip can be found in most of our everyday conversations. Why are individuals interested in hearing gossip about others' achievements and failures? Researchers at the University of Groningen in the Netherlands studied the effect positive and negative gossip has on how the recipient evaluates him or herself. The study is published in Personality and Social Psychology Bulletin.

The Lancet: The hidden truth about the health of homeless people

As many as 4 million Europeans and 3.5 million Americans experience homelessness every year, and the numbers are rising. Homeless people 'are the sickest in our society,' but just treating ill health might not be enough to help get people off the streets, according to a new two-part series on homelessness in high-income countries, published in The Lancet.

Treating ill health might not be enough to help homeless people get off the streets

TORONTO, Oct. 24, 2014—Health care providers should recognize that any effective strategy to address homelessness needs to include both interventions to improve the health of homeless individuals as well as larger-scale policy changes, according to a paper published today.

Nation's 'personality' influences its environmental stewardship, shows new study

Toronto – Countries with higher levels of compassion and openness score better when it comes to environmental sustainability, says research from the University of Toronto.

A new study by Jacob Hirsh, an Assistant Professor of Organizational Behaviour & Human Resource Management at the University of Toronto Mississauga's Institute for Management & Innovation, who is cross-appointed to UofT's Rotman School of Management, demonstrates that a country's personality profile can predict its environmental sustainability records.

Costs to treat bleeding strokes increases 10 years later

Costs to treat strokes caused by bleeding in the brain may increase significantly 10 years later, according to a study in the American Heart Association journal Stroke.

The Australian study is the first to include 10 years of follow-up data on stroke cost estimates, which may also apply to the United States, researchers said.

UT Southwestern scientists discover new clues to how weight loss is regulated

DALLAS – Oct. 23, 2014 – A hormone seen as a popular target to develop weight-loss drugs works by directly targeting the brain and triggering previously unknown activity in the nervous system, UT Southwestern Medical Center obesity researchers have found.

The fibroblast growth factor 21 (FGF21) hormone has been a key target for developing weight-loss drugs because the protein increases energy expenditure, causing the body to burn calories. But how the hormone worked wasn't known until now.

New insight on why people with Down syndrome invariably develop Alzheimer's disease

La Jolla, Calif., October 23, 2014 –A new study by researchers at Sanford-Burnham Medical Research Institute reveals the process that leads to changes in the brains of individuals with Down syndrome—the same changes that cause dementia in Alzheimer's patients. The findings, published in Cell Reports, have important implications for the development of treatments that can prevent damage in neuronal connectivity and brain function in Down syndrome and other neurodevelopmental and neurodegenerative conditions, including Alzheimer's disease.

Bradley Hospital finds sleep difficulties common among toddlers with psychiatric disorders

PROVIDENCE, R.I. – John Boekamp, Ph.D., clinical director of the Pediatric Partial Hospital Program (PPHP) at Bradley Hospital recently led a study that found sleep difficulties - particularly problems with falling asleep - were very common among toddlers and preschool-aged children who were receiving clinical treatment for a wide range of psychiatric disorders. The study, titled "Sleep Onset and Night Waking Insomnias in Preschoolers with Psychiatric Disorders," is now published online in the journal Child Psychiatry & Human Development.