Brain

A study led by investigators from Massachusetts General Hospital and the Perelman School of Medicine at the University of Pennsylvania has identified a potential target for therapies to treat cocaine addiction. In their study receiving advance online publication in Molecular Psychiatry, the investigators find evidence that changing one amino acid in a subunit of an important receptor protein alters whether cocaine-experienced animals will resume drug seeking after a period of cocaine abstinence.

Researchers at University of California, San Diego School of Medicine have validated an EEG test to study and treat schizophrenia. The findings, published in two separate studies, offer a clinical test that could be used to help diagnose persons at risk for developing mental illness later in life, as well as an approach for measuring the efficacies of different treatment options.

The way a person's brain responds to a single disgusting image is enough to reliably predict whether he or she identifies politically as liberal or conservative. As we approach Election Day, the researchers say that the findings reported in the Cell Press journal Current Biology on October 30 come as a reminder of something we all know but probably don't always do: "Think, don't just react."

If the surroundings are designed to be sufficiently stimulating, even a simple computer screen is enough to generate an intense cinematic experience. After observing some 300 study subjects, researchers at the Institute of Psychology of Johannes Gutenberg University Mainz (JGU) in Germany concluded that the angle of viewing does not play a vital role in the cinematic experience, thus disproving various hypotheses. According to the results of their study, the presence of so-called contextual visual cues plays a greater role in actually drawing viewers into a movie.

Walking workstations can improve not only physical, but also mental health during the workday, a new study released this week found. The research was conducted by faculty and student researchers from the Department of Psychology in the School of Science at Indiana University-Purdue University Indianapolis (IUPUI).

With growing concerns regarding obesity in the United States, Michael Sliter, assistant professor of psychology, hopes the study encourages employers to examine methods to assist workers in in healthy living.

A new technology that may assist in the treatment of brain cancer and other neurological diseases is the subject of an article in a recent issue of the journal Technology, published by World Scientific Publishing Company.

According to the authors, the current medical use of chemotherapy to treat brain cancer can be inefficient because of the blood-brain-barrier that impedes the delivery of drugs out of blood vessels and into the tumor.

Philadelphia, PA, October 29, 2014 – Ghrelin is a hormone released by the stomach and it stimulates appetite and food intake. Alcohol is commonly viewed as a psychoactive substance that primarily affects brain function, but it is also a highly caloric food.

This knowledge, combined with findings from animal studies, led researchers to the hypothesis that ghrelin has the potential to stimulate alcohol craving.

The research team previously identified that changes in the brain occur two decades before patients show signs of dementia. These changes can be detected through expensive brain imaging procedures.

The new early detection blood-test could predict these changes and a person's risk of developing AD much earlier than is currently possible.

The blood test has the potential to improve prediction for AD to 91 per cent accuracy. However, this needs to be further tested in a larger population across three to five years, due to AD being a progressive disease.

CAPE TOWN, October 29, 2014 – Many of the women at first acted surprised. Some insisted the blood tests were wrong. But most conveyed to researchers why they had not used the study products assigned to them as participants in VOICE, a large HIV prevention trial that, as a likely consequence, did not find any of the three products that were tested to be effective.

OAK BROOK, Ill. – Researchers using a combination of different imaging techniques have found structural abnormalities in the brains of people with chronic fatigue syndrome (CFS), according to a new study published online in the journal Radiology. The results suggest a potential role for imaging in diagnosing and treating the condition.

An imaging study by Stanford University School of Medicine investigators has found distinct differences between the brains of patients with chronic fatigue syndrome and those of healthy people.

The findings could lead to more definitive diagnoses of the syndrome and may also point to an underlying mechanism in the disease process.

Glioma is a common name for serious brain tumours. Different types of glioma are usually diagnosed as separate diseases and have been considered to arise from different cell types in the brain. Now researchers at Uppsala University, together with American colleagues, have shown that one and the same cell of origin can give rise to different types of glioma. This is important for the basic understanding of how these tumours are formed and can contribute to the development of more efficient and specific glioma therapies. The results have been published in Journal of Neuroscience.

AMHERST, Mass. – Binge drinking can have lasting effects on brain pathways that are still developing during adolescence, say neuroscience researcher Heather N. Richardson and her colleagues at the University of Massachusetts Amherst and Louisiana State University. Results of their study using a rodent model of adolescent drinking appear in the October 29 issue of The Journal of Neuroscience.

WASHINGTON, DC — Heavy drinking during adolescence may lead to structural changes in the brain and memory deficits that persist into adulthood, according to an animal study published October 29 in The Journal of Neuroscience. The study found that, even as adults, rats given daily access to alcohol during adolescence had reduced levels of myelin — the fatty coating on nerve fibers that accelerates the transmission of electrical signals between neurons. These changes were observed in a brain region important in reasoning and decision-making.

In addition to their song, songbirds also have an extensive repertoire of calls. While the species-specific song must be learned as a young bird, most calls are, as in the case of all other birds, innate. Researchers at the Max Planck Institute in Seewiesen have now discovered that in zebra finches the song control system in the brain is also active during simple communication calls. This relationship between unlearned calls and an area of the brain responsible for learned vocalisations is important for understanding the evolution of song learning in songbirds.