Brain

Link between intensive post-stroke rehabilitation and recovery demonstrated in rats

Okazaki, Japan - Each year millions of people worldwide suffer from stroke, which can occur to anyone at any time. While some may recover completely, the majority of survivors will experience some form of impairment that requires a lengthy process toward partial or full recovery of functioning. Therefore, continuous improvement of rehabilitation methods is needed to ensure more positive long-term outcomes among survivors.

Untreated high blood pressure significantly increases risk of bleeding stroke

LOS ANGELES, Feb. 18, 2016 - Left untreated, high blood pressure may significantly increase your risk of developing a brain bleed, according to research presented at the American Stroke Association's International Stroke Conference 2016.

Intracerebral hemorrhage is a type of stroke caused by a weakened blood vessel that ruptures and bleeds into brain tissue. High blood pressure is a powerful determinant of risk for intracerebral hemorrhage.

Young people with mental problems should receive help in their own environment

Young people with mental problems - especially those with psychotic-like symptoms - should receive help as early as possible and in their own environment. This was the conclusion of a joint study of the University of Helsinki, the Helsinki University Hospital Department of Psychiatry and the National Institute for Health and Welfare, Finland.

Novel combination of ingredients may offer greater support for infant brain development

URBANA, Ill. - Research has shown that nutrition plays an important role in the rapid structural development of the brain during the first few months of life. Scientists at the University of Illinois interested in this connection have studied the neonatal piglet as a model of human brain and cognitive development for nearly a decade.

New insights into epilepsy drug Retigabine

A study published ahead of print in the The Journal of General Physiology has revealed new insights into Retigabine, a known pharmacological treatment for epilepsy.

Migraine with aura linked to clot-caused strokes

LOS ANGELES, Feb. 17, 2016 -- People who have migraines with aura are more likely to have strokes caused by either a blood clot in the heart (cardio-embolic stroke) or a clot within the brain's blood vessels (thrombotic stroke), compared to those that don't have migraines with aura, according to research presented at the American Stroke Association's International Stroke Conference 2016.

Cost of effective stroke clot-busting drug outpaces reimbursement

LOS ANGELES, February 17, 2016 - The cost of an effective, widely used clot-busting drug has more than doubled over the past decade, but Medicare/Medicaid reimbursement lags far behind, according to research presented at the American Stroke Association's International Stroke Conference 2016.

Pregnancy in older age increases stroke, heart attack risk years later

LOS ANGELES, Feb. 17, 2016 - Women who become pregnant at age 40 or older face a greater risk of stroke and heart attack later in life than women who become pregnant at a younger age, according to research presented at the American Stroke Association's International Stroke Conference 2016.

Common antibiotics may be linked to temporary mental confusion

MINNEAPOLIS - Antibiotics may be linked to a serious disruption in brain function, called delirium, and other brain problems, more than previously thought, according to a "Views and Reviews" article published in the Feb. 17, 2016, online issue of Neurology®, a medical journal of the American Academy of Neurology.

Delirium causes mental confusion that may be accompanied by hallucinations and agitation. Medications are often the cause of delirium, but antibiotics are not necessarily the first medications doctors may suspect.

Diabetes drug may prevent recurring strokes

Pioglitazone, a drug used for type 2 diabetes, may prevent recurrent stroke and heart attacks in people with insulin resistance but without diabetes. The results of the Insulin Resistance Intervention after Stroke (IRIS) trial, presented at the International Stroke Conference 2016 in Los Angeles and published in the New England Journal of Medicine, suggest a potential new method to prevent stroke and heart attack in high-risk patients who have already had one stroke or transient ischemic attack.

Stenting as effective as endarterectomy for preventing strokes in asymptomatic patients

The most modern clinical trial to compare the use of carotid-artery stenting with carotid endarterectomy for the prevention of strokes in asymptomatic patients with serious narrowing of the carotid artery finds no significant differences in outcomes between the two procedures over a period of up to five years. The results are receiving Online First publication in the New England Journal of Medicine to coincide with their presentation at the International Stroke Conference in Los Angeles.

Caltech biologists identify gene that helps regulate sleep

Caltech biologists have performed the first large-scale screening in a vertebrate animal for genes that regulate sleep, and have identified a gene that when overactivated causes severe insomnia. Expression of the gene, neuromedin U (Nmu), also seems to serve as nature's stimulant--fish lacking the gene take longer to wake up in the morning and are less active during the day.

A new molecular alarm clock in vertebrates

Dozens of chemical interactions in the vertebrate brain go into maintaining a natural sleep schedule, and scientists have recently found one more player on the field: a neurochemical called neuromedin U, or Nmu. The protein, which was analyzed in zebrafish but is also found in humans, acts to stimulate wakefulness, particularly in the morning. The study appears Feb. 17, 2016 in Neuron.

Study of firefighters finds potential pathway between insomnia and depression

DARIEN, IL - A new study of firefighters suggests that insomnia and nightmares may increase the risk of depression by impairing the ability to access and leverage emotion regulation strategies effectively.

Imaging, not time, may determine who is right for stroke clot removal

LOS ANGELES, Feb.16, 2016 - Brain imaging may accurately identify patients likely to benefit from stroke clot removal instead of relying on the time since symptoms began as an indicator of treatment eligibility, according to research presented at the American Stroke Association's International Stroke Conference 2016.