Brain

Stem cells used to reverse paralysis in animals

Valencia, Spain – January 28, 2009 – A new study has found that transplantation of stem cells from the lining of the spinal cord, called ependymal stem cells, reverses paralysis associated with spinal cord injuries in laboratory tests. The findings show that the population of these cells after spinal cord injury was many times greater than comparable cells from healthy animal subjects. The results open a new window on spinal cord regenerative strategies. The study is published in the journal Stem Cells.

What happens when we sleep

Did I see what I think I saw?

Eyewitness testimony is a crucial part of many criminal trials even though research increasingly suggests that it may not be as accurate as we (and many lawyers) would like it to be. For example, if you witness a man in a blue sweater stealing something, then overhear people talking about a gray shirt, how likely are you to remember the real color of the thief's sweater? Studies have shown that when people are told false information about an event, they become less likely to remember what actually happened - it is easy to mix up the real facts with fake ones.

Support cells, not neurons, lull the brain to sleep

Brain cells called astrocytes help to cause the urge to sleep that comes with prolonged wakefulness, according to a study in mice, funded by the National Institutes of Health. The cells release adenosine, a chemical known to have sleep-inducing effects that are inhibited by caffeine.

New laser for neurosurgery allows greater precision and efficiency for removal of complex tumors

CHICAGO – Surgeons at Northwestern Memorial Hospital are among the first in the country to use a new micro-laser, which uses light energy in place of a cutting tool to remove complicated brain and spine tumors. The technique offers greater precision and efficiency during surgery, reducing the incision size, surgery time and patient recovery period following surgery.

CSHL scientists clarify editing error underlying genetic neurodegenerative disease

Two molecular biologists at Cold Spring Harbor Laboratory have uncovered important new details about how a gene mutation causes a cellular editing error that results in a devastating disease called pontocerebellar hypoplasia (PCH). The new findings were published online, ahead of print, on January 25th in the journal Nature Structural and Molecular Biology.

First gene discovered for most common form of epilepsy

NEW YORK (January 28, 2009) - An international team of researchers, led by investigators at Columbia University Medical Center, has uncovered the first gene linked to the most common type of epilepsy, called Rolandic epilepsy. One out of every five children with epilepsy is diagnosed with this form, which is associated with seizures starting in one part of the brain.

Results of the study were published in an advance online issue of the European Journal of Human Genetics on January 28, 2009.

Newborn brain cells 'time-stamp' memories

LA JOLLA, CA—"Remember when…?" is how many a wistful trip down memory lane begins. But just how the brain keeps tabs on what happened and when is still a matter of speculation. A computational model developed by scientists at the Salk Institute for Biological Studies now suggests that newborn brain cells—generated by the thousands each day—add a time-related code, which is unique to memories formed around the same time.

Astrocytes regulate sleep pressure and memory deficits associated with sleep deprivation

Scientists have discovered an unexpected brain mechanism that modulates the regulation of sleep and the consequences of sleep deprivation. The research, published by Cell Press in the January 29th issue of the journal Neuron, opens new avenues for development of treatments for disorders and cognitive deficits associated with sleep loss.

Surprising discoveries contribute to memory research

EVANSTON, Ill. --- Like countless neuroscientists around the world, Northwestern University Professor Nelson Spruston knew H. M. well -- his personal story and the sound of his voice. But it wasn't until H. M. died last month that Spruston learned H. M.'s full name -- Henry Gustav Molaison.

Blast overpressure is generated from the firing of weapons and may cause brain injury

The brain may be injured by the noise, which is produced when, for example, an anti-tank weapon (Bazooka, Karl Gustav) or a howitzer (Haubits) is fired. Scientists at the Sahlgrenska Academy demonstrated mild injury to brain tissue. In response to this, the Swedish Armed Forces restricted the number of rounds per day Swedish personnel can be exposed to.

New study highlights the distress of medical staff

Whilst losing a baby is distressing for parents, until now it has been less widely acknowledged that medical staff themselves can be affected by the losses experienced by their patients.

New research from the University of Leicester shows that staff working in obstetrics and gynaecology, caring for families experiencing loss, can also experience significant and clinical levels of distress.Senior staff and those with significant experience can be affected as much as their junior colleagues.

Spinal fluid proteins signal Lou Gehrig's disease

High levels of certain proteins in the spinal fluid could signal the onset of Lou Gehrig's disease, according to researchers. The discovery of these biomarkers may lead to diagnostic kits for early diagnosis, accurately measuring the progression of the disease and monitoring the effects of treatment.

Weizmann Institute scientists create working artificial nerve networks

Scientists have already hooked brains directly to computers by means of metal electrodes, in the hope of both measuring what goes on inside the brain and eventually healing conditions such as blindness or epilepsy. In the future, the interface between brain and artificial system might be based on nerve cells grown for that purpose. In research that was recently featured on the cover of Nature Physics, Prof. Elisha Moses of the Physics of Complex Systems Department and his former research students Drs.

Is technology producing a decline in critical thinking and analysis?

As technology has played a bigger role in our lives, our skills in critical thinking and analysis have declined, while our visual skills have improved, according to research by Patricia Greenfield, UCLA distinguished professor of psychology and director of the Children's Digital Media Center, Los Angeles.