Brain

UVA scientists use synthetic gene and magnets to alter behavior of mice, fish

University of Virginia scientists have demonstrated that neurons in the brain that have been supplemented with a synthetic gene can be remotely manipulated by a magnetic field. The finding has implications for possible future treatment of a range of neurological diseases, such as schizophrenia and Parkinson's disease.

Scientists map roots of premeditated, violent 'intent' in animal brain

The bad intentions that often precede violence originate in a specific brain region, according to a study in mice led by researchers from NYU Langone Medical Center and published in Nature Neuroscience online March 7.

Alzheimer's more versatile than previously known

Accumulation of the substance amyloid beta in the brain impairs the memory and cognitive ability in people with Alzheimer's. New findings from Lund University in Sweden show that the cause of amyloid beta pathology might be more versatile than previously known. Researchers believe that these new findings may be of significance to the development of new medications.

AI crossword-solving application could make machines better at understanding language

Researchers have designed a web-based platform which uses artificial neural networks to answer standard crossword clues better than existing commercial products specifically designed for the task. The system, which is freely available online, could help machines understand language more effectively.

New mothers with postpartum psychiatric disorders face increased risk of suicide: Study

Over a period spanning four decades, a total of eight Danish women committed suicide within a year of being diagnosed with a birth-related psychiatric disorder, including severe episodes of postpartum depression or psychosis. Despite the modest number, statistical evidence of a causal link between postpartum disorder and suicide is extremely strong, highlighting the need for medical staff to be aware of the risk, according to the researchers who carried out the study.

The brain's gardeners: Immune cells 'prune' connections between neurons

A new study out today in the journal Nature Communications shows that cells normally associated with protecting the brain from infection and injury also play an important role in rewiring the connections between nerve cells. While this discovery sheds new light on the mechanics of neuroplasticity, it could also help explain diseases like autism spectrum disorders, schizophrenia, and dementia, which may arise when this process breaks down and connections between brain cells are not formed or removed correctly.

Scientists tap the smarts of mice, capture problem-solving in action

Scientists at the University of California, Berkeley, have captured unique images of problem-solving in action by tapping into the minds of mice. The study shows rapid rewiring in the frontal brains of mice after they learn by trial and error.

Using advanced microscopy techniques, researchers found that when mice used new strategies to find hidden treats during a foraging task, they showed a dramatic resculpting of their frontal lobes.

Overconfidence linked to one's view of intelligence

PULLMAN, Wash.--Washington State University researcher Joyce Ehrlinger has found that a person's tendency to be overconfident increases if he or she thinks intelligence is fixed and unchangeable.

Latin dancing may have health benefits for older adults

PHOENIX, March 4, 2016 -- A four-month dance program helped older Latino adults walk faster and improved their physical fitness, which may reduce their risk for heart disease, according to research presented at the American Heart Association's Epidemiology/Lifestyle 2016 Scientific Sessions.

Protection against peanut allergy by early consumption persists after 1 year of avoidance

WA, Seattle (March 4, 2016) - Peanut allergy prevention achieved from early peanut consumption in at-risk infants persists after a one-year period of avoiding peanut, a clinical trial has found. The LEAP-ON clinical trial (Persistence of Oral Tolerance to Peanut) was conducted by the Immune Tolerance Network (ITN), a research consortium supported by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, and led by Dr. Gideon Lack from Kings College London.

Eating peanut in early years helps reduce risk of allergy even with later abstinence

The early introduction of peanut to the diets of infants at high-risk of developing peanut allergy significantly reduces the risk of peanut allergy until 6 years of age, even if they stop eating peanut around the age of five, according to a new study led by King's College London.

Building a better mouse trap, from the atoms up

For most of human history, the discovery of new materials has been a crapshoot. But now, UConn researchers have systematized the search with machine learning that can scan millions of theoretical compounds for qualities that would make better solar cells, fibers, and computer chips. The search for new materials may never be the same.

Zika virus infects human neural stem cells

The Zika virus infects a type of neural stem cell that gives rise to the brain's cerebral cortex, Johns Hopkins and Florida State researchers report March 4 in Cell Stem Cell. On laboratory dishes, these stem cells were found to be havens for viral reproduction, resulting in cell death and/or disruption of cell growth. While this study does not prove the direct link between Zika and microcephaly, it does pinpoint where the virus may be doing the most damage.

Florida State University researchers make Zika virus breakthrough

TALLAHASSEE, Fla. -- Florida State University researchers have made a major breakthrough in the quest to learn whether the Zika virus is linked to birth defects with the discovery that the virus is directly targeting brain development cells and stunting their growth.

This is the first major finding by scientists that shows that these critical cells are a target of the virus and also negatively affected by it. Hengli Tang, professor of biological science at FSU, is a lead author of the study published today (March 4) in the academic journal Cell Stem Cell.

Likely biological link found between Zika virus, microcephaly

Working with lab-grown human stem cells, a team of researchers suspect they have discovered how the Zika virus probably causes microcephaly in fetuses. The virus selectively infects cells that form the brain's cortex, or outer layer, making them more likely to die and less likely to divide normally and make new brain cells.

The researchers say their experiments also suggest these highly-susceptible lab-grown cells could be used to screen for drugs that protect the cells or ease existing infections.