Brain

(BOSTON) – The Center for the Study of Traumatic Encephalopathy (CSTE) at Boston University School of Medicine (BUSM) announced today that a deceased former college football player who died at age 42 was already suffering from the degenerative brain disease, Chronic Traumatic Encephalopathy (CTE). This is the first time an advanced case of CTE has been discovered in a college football player that did not play professionally. It is also the first case diagnosed in a wide receiver.

Last year the UK government reclassified cannabis from a class C to a class B drug, partly out of concerns that cannabis, especially the more potent varieties, may increase the risk of schizophrenia in young people. But the evidence for the relationship between cannabis and schizophrenia or psychosis remains controversial. A new study has determined that it may be necessary to stop thousands of cannabis users in order to prevent a single case of schizophrenia.

A new study in China has found that people with higher levels of pesticide exposure are more likely to have suicidal thoughts. The study was carried out by Dr Robert Stewart from the Institute of Psychiatry at King's College London together with scientists from Tongde Hospital Zhejiang Province.

Groups of neurons that precisely keep time have been discovered in the primate brain by a team of researchers that includes Dezhe Jin, assistant professor of physics at Penn State University and two neuroscientists from the RIKEN Brain Science Institute in Japan and the Massachusetts Institute of Technology (MIT). "This research is the first time that precise time-keeping activities have been identified in recordings of neuron activity," Jin said.

Philadelphia, PA, 22 October 2009 - There are increasingly precise molecular insights into ways that stress exposure leads to fear and through which fear extinction resolves these fear states. Extinction is generally regarded as new inhibitory learning, but where the inhibition originates from remains to be determined. Gamma-aminobutyric acid (GABA), the primary inhibitory chemical messenger in the brain, seems to be very important to these processes.

Philadelphia, PA, 22 October 2009 - After exposure to extreme life stresses, what distinguishes the individuals who do and do not develop posttraumatic stress disorder (PTSD)? A new study, published in the October 1st issue of Biological Psychiatry, suggests that it has something to do with the way that we control the activity of the prefrontal cortex, a brain region thought to orchestrate our thoughts and actions.

DURHAM, N.C. – Researchers at Duke University Medical Center have uncovered a new genetic signature that correlates strongly with autism and which doesn't involve changes to the DNA sequence itself. Rather, the changes are in the way the genes are turned on and off. The finding may suggest new approaches to diagnosis and treatment of autism.

The researchers found higher-than-usual numbers of gene-regulating molecules called methyl groups in a region of the genome that regulates oxytocin receptor expression in people with autism.

CHAMPAIGN, Ill. — Rats exposed to high doses of amphetamines at an age that corresponds to the later years of human adolescence display significant memory deficits as adults – long after the exposure ends, researchers report.

The declines in short-term or "working" memory are most pronounced when the rats are exposed during adolescence, rather than as adults, the researchers found.

Rockville, MD — Although we assume we can see everything in our field of vision, the brain actually picks and chooses the stimuli that come into our consciousness. A new study in the Association for Research in Vision and Ophthalmology's Journal of Vision reveals that our brains can be trained to consciously see stimuli that would normally be invisible.

Lead researcher Caspar Schwiedrzik from the Max Planck Institute for Brain Research in Germany said the brain is an organ that continuously adapts to its environment and can be taught to improve visual perception.

NEW YORK (October 21, 2009) -- A 50-year-old New York woman who was diagnosed with a progressive blinding disease at age 13 was implanted with an experimental electronic eye implant that has partially restored her vision. A team led by Dr. Lucian V. Del Priore at NewYork-Presbyterian Hospital/Columbia University Medical Center performed the June 26 surgery -- the first case of its kind in New York.

The first treatment aimed at restoring limited sight in people blinded by retinal disease, it is currently available as part of a multicenter clinical trial.

COLUMBUS, Ohio – The inflammatory response following a spinal cord injury appears to be set up to cause extra tissue damage instead of promoting healing, new research suggests.

Scientists analyzing this inflammatory response in mice discovered that the types of cells recruited to the site of the injury are dominated within a week by those that promote inflammation. When chronic, inflammation can prevent healing, and these inflammatory cells are believed to remain at the injury site indefinitely.

Few internists who care for cancer survivors address issues of sexual dysfunction with their patients, according to a study led by Massachusetts General Hospital (MGH) researchers. In their article appearing in a November 2009 cancer survivor supplement to the Journal of General Internal Medicine, now available online, the investigators report that more than half the internists responding to a survey indicated they rarely or never discussed sexual problems with their patients who had survived cancer.

Irvine, Calif., Oct. 21, 2009 – The eyes may be the windows to the soul, but new research indicates they also may mirror a brain ravaged by Alzheimer's disease.

UC Irvine neuroscientists have found that retinas in mice genetically altered to have Alzheimer's undergo changes similar to those that occur in the brain – most notably the accumulation of amyloid plaque lesions.

Montreal, October 21, 2009 – Women are better than men at distinguishing between emotions, especially fear and disgust, according to a new study published in the online version of the journal Neuropsychologia. As part of the investigation, Olivier Collignon and a team from the Université de Montréal Centre de recherche en neuropsychologie et cognition (CERNEC) demonstrated that women are better than men at processing auditory, visual and audiovisual emotions.

COLUMBUS, Ohio – People with relatively extreme opinions may be more willing to publicly share their views than those with more moderate views, according to a new study.

The key is that the extremists have to believe that more people share their views than actually do, the research found.

The results may offer one possible explanation for our fractured political climate in the United States, where extreme liberal and conservative opinions often seem to dominate.