Brain

Diabetes drug shows promise against multiple sclerosis

A drug currently FDA-approved for use in diabetes shows some protective effects in the brains of patients with relapsing remitting multiple sclerosis, researchers at the University of Illinois at Chicago College of Medicine report in a study currently available online in the Journal of Neuroimmunology.

Intervention helps to reduce pain and depression

For patients who experience pain and depression, common co-existing conditions, an intervention that included individually tailored antidepressant therapy and a pain self-management program resulted in greater improvement in the symptoms of these conditions than patients who received usual care, according to a study in the May 27 issue of JAMA.

Effectively managing pain with depression - JAMA

INDIANAPOLIS – Pain, the most common reason for adults to visit a primary care physician, and depression, the most frequent mental complaint requiring a doctor's appointment, occur together as often as half the time.

Researchers from the Indiana University School of Medicine and the Regenstrief Institute report in the May 27 issue of the Journal of the American Medical Association (JAMA) that a strategy they developed of closely monitored antidepressant therapy coupled with pain self-management can produce substantial improvements in both depression and pain.

Mayo Clinic Proceedings: The evolution of migraine from episodic headache to chronic disorder

ROCHESTER, Minn. -- Patients living with migraine have strong reason for new optimism concerning a positive future. Two review articles and an accompanying editorial, "The Future of Migraine: Beyond Just Another Pill," in the current issue of Mayo Clinic Proceedings, are the basis for an ironic premise.

Scientists reaching consensus on how brain processes speech

Washington, DC – Neuroscientists feel they are much closer to an accepted unified theory about how the brain processes speech and language, according to a scientist at Georgetown University Medical Center who first laid the concepts a decade ago and who has now published a review article confirming the theory.

Is vitamin D deficiency linked to Alzheimer's disease and vascular dementia?

Amsterdam, The Netherlands, May 26, 2009 – There are several risk factors for the development of Alzheimer's disease and vascular dementia. Based on an increasing number of studies linking these risk factors with Vitamin D deficiency, an article in the current issue of the Journal of Alzheimer's Disease (May 2009) by William B. Grant, PhD of the Sunlight, Nutrition, and Health Research Center (SUNARC) suggests that further investigation of possible direct or indirect linkages between Vitamin D and these dementias is needed.

Poor attention in kindergarten predicts lower high school test scores, UC Davis researchers find

(SACRAMENTO, Calif.) — As thousands of students nationwide prepare to leave high school, a UC Davis study appearing online today in the June issue of the medical journal Pediatrics shows a clear link between attention problems early in school — as early as kindergarten — and lower high school test scores.

Brain-behavior disconnect in cocaine addiction

UPTON, NY — Parts of the brain involved in monitoring behaviors and emotions show different levels of activity in cocaine users relative to non-drug users, even when both groups perform equally well on a psychological test. These results — from a brain-imaging study conducted at the U.S.

Nervous system may be culprit in deadly muscle disease

GAINESVILLE, Fla. — Brain may win out over brawn as the primary cause of breathing problems in children with a severe form of muscular dystrophy known as Pompe disease.

Researchers at the Powell Gene Therapy Center at the University of Florida have discovered that signals from the brain to the diaphragm — the muscle that controls breathing — are too weak to initiate healthy respiration in mouse models of the disease.

Sociality and brain size? Not so, says researcher

Packs of hunting dogs, troops of baboons, herds of antelope: when people observe social animals, they are often struck by how intelligent they seem, and recent studies suggest that sociality has played a key role in the evolution of larger brain size among several orders of mammals.

Some neural tube defects in mice linked to enzyme deficiency

St. Louis, May 25, 2009 — Women of childbearing age can reduce the risk of having a child born with a neural tube defect such as spina bifida by eating enough folate or folic acid. However, folate prevents only about 70 percent of these defects.

New research using mice at Washington University School of Medicine in St. Louis confirms the importance of another nutrient, inositol, to protect against the development of neural tube defects.

Menopause transition may cause trouble learning

ST. PAUL, Minn. – The largest study of its kind to date shows that women may not be able to learn as well shortly before menopause compared to other stages in life. The research is published in the May 26, 2009, print issue of Neurology®, the medical journal of the American Academy of Neurology.

For a four-year period, researchers studied 2,362 women, who were between the ages of 42 and 52 had at least one menstrual period in the three months before the study started.

Survey suggests higher risk of falls due to dizziness in middle-aged and older Americans

A full third of American adults, 69 million men and women over age 40, are up to 12 times more likely to have a serious fall because they have some form of inner-ear dysfunction that throws them off balance and makes them dizzy, according to Johns Hopkins experts.

Among the other key findings of the three-year survey and study on the subject by the Johns Hopkins team are that a third of this group, or more than 22 million, were unaware of their vulnerability, having had no previous incidents of disequilibrium or sudden falls to suggest that anything was wrong.

Major histocompatibility complexes -- how genetics influences humans to choose their mates

Vienna, Austria: New light has been thrown on how humans choose their partners, a scientist will tell the annual conference of the European Society of Human Genetics today (Monday May 25). Professor Maria da Graça Bicalho, head of the Immunogenetics and Histocompatibility Laboratory at the University of Parana, Brazil, says that her research had shown that people with diverse major histocompatibility complexes (MHCs) were more likely to choose each other as mates than those whose MHCs were similar, and that this was likely to be an evolutionary strategy to ensure healthy reproduction.

Psychologists find that head movement is more important than gender in nonverbal communication

May 21, 2009 — It is well known that people use head motion during conversation to convey a range of meanings and emotions, and that women use more active head motion when conversing with each other than men use when they talk with each other.

When women and men converse together, the men use a little more head motion and the women use a little less. But the men and women might be adapting because of their gender-based expectations or because of the movements they perceive from each other.