Body

Safe seed: Food cotton genetically modified to not have toxic gossypol

Field trials of a new cotton are verifying previous lab and greenhouse studies indicating the crop could become a source of protein for millions of malnourished people in the world.

The cotton was engineered so that the toxic gossypol is reduced to tolerable levels in the high-protein seed but remain at higher levels in the rest of the plant to ward off pests and disease.

"The results look very promising." said Dr. Keerti Rathore, the Texas AgriLife Research plant biotechnologist in whose lab the cotton was developed.

Large thighs protect against heart disease and early death

Men and women whose thighs are less than 60cm in circumference have a higher risk of premature death and heart disease, according to research published on bmj.com today. The study also concluded that individuals whose thighs are wider than 60cm have no added protective effect.

Lead author, Professor Berit Heitmann, based at Copenhagen University Hospital, says his research may help GPs identify patients who are at an increased risk of early death and developing heart disease.

Research team discovers switch that causes the body to produce cancerous cells

A team of Syracuse University researchers discovered a second molecular switch within the Mixed Lineage Leukemia protein complex that they believe could be exploited to prevent the overproduction of abnormal cells that are found in several types of cancer, including leukemia.

Web page ranking algorithm detects critical species in ecosystems

Google's algorithm for ranking web-pages can be used to determine which species are critical for sustaining ecosystems. Drs. Stefano Allesina and Mercedes Pascual find that "PageRank" can be applied to the study of food webs, the complex networks describing who eats whom in an ecosystem.

Molecular decay of enamel-specific gene in toothless mammals supports theory of evolution

RIVERSIDE, Calif. – Biologists at the University of California, Riverside report new evidence for evolutionary change recorded in both the fossil record and the genomes (or genetic blueprints) of living organisms, providing fresh support for Charles Darwin's theory of evolution.

The researchers were able to correlate the progressive loss of enamel in the fossil record with a simultaneous molecular decay of a gene, called the enamelin gene, that is involved in enamel formation in mammals.

How to improve vaccines to trigger T cell as well as antibody response

Killed or disabled viruses have proven safe and effective for vaccinating billions worldwide against smallpox, polio, measles, influenza and many other diseases.

But killed or severely "attenuated" vaccines, which are safer than "live" vaccines, have been largely unsuccessful for many non-viral diseases, including illnesses like tuberculosis and malaria.

Current national primary care policies for childhood obesity need to be improved

Current primary care policies aimed at reducing obesity and increasing physical activity in children do not work and are very costly to run, according to research published on bmj.com today.

Molecular 'GPS' helps researchers probe processes important in aging and disease

ANN ARBOR, Mich.---With all the hype about beneficial antioxidants in everything from face cream to cereal bars, you'd think their targets---oxygen radicals---must be up to no good. It's true, the buildup of oxygen radicals and other reactive oxygen species (ROS) in cells contributes to aging and possibly to diseases such as cancer and Alzheimer's.

But in moderate amounts, ROS also help keep cells healthy by controlling cell division, movement and other normal biological processes.

Argonne researchers develop method that aims to stabilize antibodies

ARGONNE, IL (Sept. 3, 2009) -- Researchers at the U.S. Department of Energy's Argonne National Laboratory have developed a systematic method to improve the stability of antibodies. The technique could lead to better biosensors, disease therapeutics and diagnostic reagents and non-laboratory applications, including environmental remediation.

2 new antibodies found to cripple HIV

NEW YORK, NY, LA JOLLA and SAN FRANCISCO, CA, SEATTLE, WA, September 3, 2009—Researchers at and associated with the International AIDS Vaccine Initiative (IAVI), at The Scripps Research Institute, and at the biotechnology companies Theraclone Sciences and Monogram Biosciences have discovered two powerful new antibodies to HIV that reveal what may be an Achilles heel on the virus. They published their work in Science this week.

Large-scale study probes how cells fight pathogens

Scientists have deciphered a key molecular circuit that enables the body to distinguish viruses from bacteria and other microbes, providing a deep view of how immune cells in mammals fend off different pathogens. The new research, which appears in the September 3 advance online edition of the journal Science, signifies one of the first large-scale reconstructions of a mammalian circuit and offers a practical approach for unraveling the circuits that underpin other important biological systems.

Nowhere to hide: Some species are unable to adapt to climate change due to their genes

Species living in restricted environments such as the tropics may lack adequate variation in their genes and be unable to adapt to climate change, according to a new study.

Adaptation is a physiological or behavioural change that makes an organism better suited to its environment, and more likely to survive and reproduce. Because adaptations usually occur due to a change (or mutation) in a gene, species with a more varied set of genes to begin with, are likely to have a better basis for adaptation.

2 new antibodies found to cripple HIV

NEW YORK, NY, LA JOLLA and SAN FRANCISCO, CA, SEATTLE, WA, September 3, 2009—Researchers at and associated with the International AIDS Vaccine Initiative (IAVI), at The Scripps Research Institute, and at the biotechnology companies Theraclone Sciences and Monogram Biosciences have discovered two powerful new antibodies to HIV that reveal what may be an Achilles heel on the virus. They published their work in Science this week.

Indoor plants found to release volatile organic compounds

ATHENS, GA—Potted plants add a certain aesthetic value to homes and offices, bringing a touch of nature to indoor spaces. It has also been shown that many common house plants have the ability to remove volatile organic compounds—gases or vapors emitted by solids and liquids that may have adverse short- and long-term health effects on humans and animals—from indoor air.

Greening university classrooms

SAN MARCOS, TX—In today's frenetic world, many urban dwellers spend more than 80% of the day indoors. Bringing nature in to living spaces by enhancing homes and offices with ornamental plants has become another popular facet of the move to "green" our lives. In addition to their aesthetic beauty, indoor plants have been shown to offer psychological and restorative values, such as reduced tension, better coping mechanisms, and increased concentration and attention.