Body

MINNEAPOLIS/ST. PAUL (November 11, 2009) – A new study from the Masonic Cancer Center, University of Minnesota shows that patients who have acute leukemia and are transplanted with two units of umbilical cord blood (UCB) have significantly reduced risk of the disease returning. This finding has the potential to change the current medical practice of using one unit of UCB for treatment of patients who are at high risk for recurrence of leukemia and other cancers of the blood and bone marrow.

BERKELEY, CA – There is good news for the global effort to reduce the amount of lead in the environment and for the growing array of technologies that rely upon the piezoelectric effect. A lead-free alternative to the current crop of piezoelectric materials has been identified by researchers with the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California (UC), Berkeley.

Charities and other nonprofits may put their brand at risk when they partner with corporations on social responsibility (CSR) initiatives. The public can easily construe such connections as a seal of approval of the corporation by the nonprofit. That's what two marketing professors found when they examined consumer perceptions in a controlled experiment.

(Boston) - Researchers from Boston University School of Medicine (BUSM) have shown that fat collection in different body locations, such as around the heart and the aorta and within the liver, are associated with certain decreased heart functions. The study, which appears on-line in Obesity, also found that measuring a person's body mass index (BMI) does not reliably predict the amount of undesired fat in and around these vital organs.

One difficulty with fighting cancer cells is that they are similar in many respects to the body's stem cells. By focusing on the differences, researchers at Karolinska Institutet have found a new way of tackling colon cancer. The study is presented in the prestigious journal Cell.

A new study has found that young people feel differently about two types of parental control, generally viewing a type of control that's thought to be better for their development more positively. However, when parents are very controlling, young people no longer make this distinction and view both types of parental control negatively.

Cervical cancer patients with specific changes in the cancer genome have a three- or fourfold increased risk of relapse after standard treatment compared to patients without these changes, according to a study by Norwegian researchers published November 13 in the open-access journal PLoS Genetics. The research suggests that specific genetic changes are crucial steps in the progression of the disease towards an aggressive and treatment-resistant state.

A study by scientists from the University of Valencia sheds new light on how the cockroach organism works. A research team from the Cavanilles Institute for Biodiversity and Evolutionary Biology, led by professors Amparo Latorre and Andrés Moya, has shown why the German cockroach (Blatella germanica) eliminates excess nitrogen by excreting ammonia, in contrast to most terrestrial insects that commonly produce uric acid as a waste compound. The research is published November 13 in the open-access journal PLoS Genetics.

Youth development programmes that tackle deprivation and help children and young people enjoy school are successful in reducing teenage pregnancy rates, say researchers on bmj.com today.

UK teenage pregnancy rates are the highest in Western Europe and there is widespread concern that policies to reduce teenage pregnancies are not working, say the authors.

Many children with chronic kidney disease (CKD) who show normal blood pressure readings at the doctor's office have high blood pressure when tested at home, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology (JASN). The findings indicate that many CKD children are not appropriately treated for hypertension, which puts them at serious risk of developing heart disease.

ITHACA, N.Y. – The seeming invincibility of cancerous tumors may be crumbling, thanks to a promising new gene therapy that eliminates the ability of certain cells to repair themselves. Researchers at the Cornell University College of Veterinary Medicine have discovered that inactivation of a DNA repair gene called Hus1 efficiently kills cells lacking p53 -- a gene mutated in the majority of human cancers.

A paper by University of Notre Dame biologist Giles Duffield and a team of researchers offers new insights into a gene that plays a key role in modulating the body's Circadian system and may also simultaneously modulate its metabolic system. The relationship between circadian and metabolic systems the researchers describe could have important implications for understanding the higher incidence of cardiovascular disease, obesity and diabetes among shift workers.

PHILADELPHIA - An international team of scientists, led by researchers at the University of Pennsylvania School of Medicine, is taking the first step in developing a treatment for a rare genetic disorder called fibrodysplasia ossificans progressiva (FOP), in which the body's skeletal muscles and soft connective tissue turns to bone, immobilizing patients over a lifetime with a second skeleton.

Baltimore, MD (November 12, 2009) – In a novel approach at disseminating scientific research, the Johns Hopkins Malaria Research Institute (JHMRI) will hold a web summit to release the latest breakthroughs in malaria research, including new approaches to boosting mosquito immunity to malaria, mapping mosquito migrations, and the promise of a rapid sputum test that could revolutionize the way malaria is tracked and tested for in rural areas, which are hotbeds for the disease.

Contrary to more conservative customs, exercising up to the end of pregnancy has no harmful effect on the weight or size of the foetus. This is what has been indicated in a study carried out by researchers of the Universidad Politécnica de Madrid (Polytechnic University of Madrid), which also shows the positive relationship between the weight of sedentary mothers before pregnancy and the body size of their babies. The conclusions appear in the International Journal of Obesity.