Body

Women's minds and bodies don't agree about sex

Women's minds and genitals respond differently to sexual arousal, whereas in men, the responses of the body and mind are more in tune with each other, according to Assistant Professor Meredith Chivers, from Queen's University in Kingston, Canada, and her international collaborators, Michael Seto, Martin Lalumière, Ellen Laan, and Teresa Grimbos. Their meta-analysis1 of the extent of agreement between subjective ratings and physiological measures of sexual arousal in men and women is published online this week in Springer's journal Archives of Sexual Behavior.

New research findings may help stop age-related macular degeneration at the molecular level

Researchers at University College London say they have gleaned a key insight into the molecular beginnings of age-related macular degeneration, the No. 1 cause of vision loss in the elderly, by determining how two key proteins interact to naturally prevent the onset of the condition.

Researchers pin down long-elusive protein that's essential to 'life as we know it'

A team of researchers is being recognized for devising a new way to study a human protein that long has evaded close scrutiny by scientists investigating its role in the communication of important genetic messages inside a cell's nucleus to workhorse molecules found elsewhere.

FDA clears TransOral robotic surgery developed at Penn

PHILADELPHIA – A minimally invasive surgical approach developed by head and neck surgeons at the University of Pennsylvania School of Medicine has been cleared by the U.S. Food and Drug Administration (FDA). The da Vinci Surgical System (Intuitive Surgical, Inc., Sunnyvale, California) has been cleared for TransOral otolaryngologic surgical procedures to treat benign tumors and select malignant tumors in adults.

Biodegradable particles can bypass mucus, release drugs over time

Johns Hopkins University researchers have created biodegradable nanosized particles that can easily slip through the body's sticky and viscous mucus secretions to deliver a sustained-release medication cargo.

The researchers say these nanoparticles, which degrade over time into harmless components, could one day carry life-saving drugs to patients suffering from dozens of health conditions, including diseases of the eye, lung, gut or female reproductive tract.

New discovery by Harvard scientists aims to correct cellular defects leading to diabetes

A new research discovery published online in the FASEB Journal (http://www.fasebj.org) may change the perception and treatment of diabetes. That's because scientists have moved closer toward correcting the root cause of the disease rather than managing its symptoms. Specifically researchers identified a protein (G6PD protein) and its antioxidant product (NAPDH) that both prevent the death and promote the growth of cells which produce and release insulin in the pancreas (beta cells).

New year, new vitamin C discovery: It 'cures' mice with accelerated aging disease

A new research discovery published in the January 2010 print issue of the FASEB Journal (http://www.fasebj.org) suggests that treatments for disorders that cause accelerated aging, particularly Werner's syndrome, might come straight from the family medicine chest. In the research report, a team of Canadian scientists show that vitamin C stops and even reverses accelerated aging in a mouse model of Werner's syndrome, but the discovery may also be applicable to other progeroid syndromes.

A trip to the candy store might help ward off deadly burn infections

As it turns out, children were not the only ones with visions of sugar plums dancing in their heads over this past holiday season. In a new research report published in the January 2010 issue of the Journal of Leukocyte Biology, a team of scientists from the University of Texas Medical Branch and Shriners Hospitals for Children show how a compound from licorice root (glycyrrhizin from Glycyrrhiza glabra) might be an effective tool in battling life-threatening, antibiotic-resistant infections resulting from severe burns.

CSHL team determines how precursors of gene-regulating small RNAs are sorted by cellular machinery

Cold Spring Harbor, NY – A team of scientists at Cold Spring Harbor Laboratory (CSHL) has determined a hierarchical set of criteria that explain how the molecular precursors of gene-regulating small RNAs are sorted by the cellular machinery.

Targeting cancerous vessels

By lowering the level of a neuronal protein, researchers halted the growth of blood vessels that tumors rely on for survival. The findings are reported online in the Journal of Experimental Medicine (www.jem.org) on Jan. 4.

MyoD helps stem cells proliferate in response to muscle injury

The master regulator of muscle differentiation, MyoD, functions early in myogenesis to help stem cells proliferate in response to muscle injury, according to researchers at Case Western Reserve University. The study appears online Jan. 4 in the Journal of Cell Biology (www.jcb.org).

Update on vitamins and diabetic retinopathy; ethnic norms for preschoolers' eyesight

SAN FRANCISCO, CA--- This month's Ophthalmology, the journal of the American Academy of Ophthalmology, includes a research review of the effects of Vitamins C and E and magnesium on diabetic retinopathy and findings from the first large study of vision problems in Hispanic and African-American infants and young children.

Can Supplements Help People with Diabetes Avoid Retinopathy?

CocE could help curb cocaine addiction

A recent study shows that a bacterial protein may help cocaine addicts break the habit.

Cocaine esterase (CocE) is a naturally-occurring bacterial enzyme that breaks down cocaine, thereby reducing its addictive properties. The efficacy of CocE in animals and its suitability for treatment of addiction has been limited by its short half-life in the body.

Study links restless leg syndrome with erectile dysfunction in older men

Westchester, Ill. — A study in the Jan. 1 issue of the journal Sleep shows that erectile dysfunction was more common in older men with restless leg syndrome (RLS) than in those without RLS, and the magnitude of this association increased with a higher frequency of RLS symptoms.

Mystery solved: Facial cancer decimating Tasmanian devils likely began in Schwann cells

Cold Spring Harbor, N.Y. – An international team of scientists led by a Cold Spring Harbor Laboratory (CSHL) investigator has discovered that the deadly facial tumors decimating Australia's Tasmanian devil population probably originated in Schwann cells, a type of tissue that cushions and protects nerve fibers.

The discovery stems from the team's effort to carry out a genetic analysis of tumor cells. Based on these data, the scientists have identified a genetic marker to accurately diagnose the facial cancers, called devil facial tumor disease (DFTD).