Body

Analysis of microbes, immune response featured in Cold Spring Harbor Protocols

Metagenomics, the study of DNA isolated from samples of naturally occurring microbial populations, is rapidly growing. Improvements to cloning and sequencing techniques are allowing researchers to study microorganisms in environmental samples, and new knowledge of species interactions and community dynamics is emerging. The identification of microorganisms in these samples is of vital importance to interpreting the results of such studies.

New study finds low mortality risk following knee and hip replacement

ROSEMONT, Ill – Total hip and total knee replacement surgeries are highly successful and very common procedures for people experiencing pain associated with degenerative joints. With a new hip or knee, and postoperative care prescribed by their doctors, most patients are able to regain a more active lifestyle with considerably less pain.

Radiofrequency ablation safe and effective for reducing pain from bone metastases

Philadelphia, PA – Image-guided radiofrequency ablation (RFA), a minimally invasive cancer treatment which can be performed in the outpatient setting, significantly reduced the level of pain experienced by cancer patients with bone (osseous) metastases, limiting the need for strong narcotic pain management, and supporting improved patient frame of mind, according to results of an American College of Radiology Imaging Network (ACRIN) study published online in the journal Cancer.

Eavesdropping on bacterial conversations may improve chronic wound healing

BINGHAMTON, NY – Listening in on bacterial conversations could be the solution for improving chronic wound care, says a team of researchers at Binghamton University, State University of New York. Their findings have been published in the Journal of Applied Microbiology.

Head-to-head studies identify best treatment regimen for hep C

In patients with chronic hepatitis C, treatment with peginterferon alpha-2a (PegIFNα2a) plus ribavirin (RBV) better suppresses the virus to undetectable levels in the blood than treatment with peginterferon alpha-2b (PegIFNα2b) plus RBV, according to two new head-to-head studies in Gastroenterology, the official journal of the American Gastroenterological Association (AGA) Institute.

Protein central to being male plays key role in wound healing

A molecular receptor pivotal to the action of male hormones such as testosterone also plays a crucial role in the body's ability to heal, report scientists in the December issue of the Journal of Clinical Investigation.

In studies in mice, scientists at the University of Rochester Medical Center found that this receptor – the androgen receptor – delays wound healing. When scientists used an experimental compound to block the receptor, wounds healed much more quickly.

Toxicants detected in Asian monkey hair may warn of environmental threats to people and wildlife

Testing hair from Asian monkeys living close to people may provide early warnings of toxic threats to humans and wildlife, according to a study published online this week in the American Journal of Physical Anthropology.

In parts of South and Southeast Asia, macaques and people are synanthropic, which means they share the same ecological niche. They drink from identical water sources, breathe the same air, share food sources, and play on the same ground.

New finding may help baby boomers get buff

If you're an aging baby boomer hoping for a buffer physique, there's hope. A team of American scientists from Texas and Michigan have made a significant discovery about the cause of age-related muscle atrophy that could lead to new drugs to halt this natural process. This research, available online the FASEB Journal (http://www.fasebj.org), shows that free radicals, such as reactive oxygen species, damage mitochondria in muscle cells, leading to cell death and muscle atrophy.

Reducing some water flow rates may bring environmental gains

Conservation projects often attempt to enhance the water-based transport of material, energy, and organisms in natural ecosystems. River restoration, for example, commonly includes boosting maximum flow rates. Yet in some highly disturbed landscapes, restoration of natural water flows may cause more harm than good, according to a study published in the January 2010 issue of BioScience.

A single atom controls motility required for bacterial infection

CHAPEL HILL – Bacteria can swim, propelling themselves through fluids using a whip-like extension called a flaggella. They can also walk, strolling along solid surfaces using little fibrous legs called pili. It is this motility that enable some pathogenic bacteria to establish the infections – such as meningitis – that cause their human hosts to get sick or even die.

Running shoes may cause damage to knees, hips and ankles

New York, NY, January 4, 2010 – Knee osteoarthritis (OA) accounts for more disability in the elderly than any other disease. Running, although it has proven cardiovascular and other health benefits, can increase stresses on the joints of the leg. In a study published in the December 2009 issue of PM&R: The journal of injury, function and rehabilitation, researchers compared the effects on knee, hip and ankle joint motions of running barefoot versus running in modern running shoes.

Mobile homes provide satisfaction, drawbacks for rural Pennsylvania

A majority of Pennsylvania's mobile home residents say they are overwhelmingly satisfied with their homes despite problems like construction quality, social stigma and financing associated with them, according to Penn State geographers.

Virus may chauffeur useful 'packages' into plants

COLLEGE STATION – This time of year, the word "virus" conjures up a bedridden stint with coughs and chills – something everyone goes to great lengths to avoid.

But scientists for Texas AgriLife Research have gone the distance to show that at least some viruses can be put to work to help us.

A new study by Dr. Karen-Beth Scholthof and her husband Dr. Herman Scholthof, to be published in the January issue of Virology, shows that plant viruses may work like a trucking service loaded to carry freight to its destination.

New SBI and ACR recommendations suggest breast cancer screening should begin at age 40

The new recommendations from the Society of Breast Imaging (SBI) and the American College of Radiology (ACR) on breast cancer screening, published in the January issue of the Journal of the American College of Radiology (JACR), state that breast cancer screening should begin at age 40 and earlier in high-risk patients. The recommendations also suggest appropriate utilization of medical imaging modalities such as mammography, magnetic resonance imaging (MRI), and ultrasound for breast cancer screening.

St. John's wort not effective treatment for IBS, researchers say

ROCHESTER, Minn. -- A Mayo Clinic research study published in the January issue of the American Journal of Gastroenterology finds that St. John's wort is not an effective treatment for irritable bowel syndrome (IBS). While antidepressants are frequently used to treat IBS, to date, no study has examined the success of using the herbal supplement St. John's wort in treating IBS.