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Ubiquitous engineered nanomaterials cause lung inflammation, study finds

(SACRAMENTO, Calif.) -- A consortium of scientists from across the country has found that breathing ultrafine particles from a large family of materials that increasingly are found in a host of household and commercial products, from sunscreens to the ink in copy machines to super-strong but lightweight sporting equipment, can cause lung inflammation and damage.

Single, high-dose erythropoietin given 2 days pre-op reduces need for transfused blood

Minneapolis, MN, May 6, 2013 – Anemia increases operative mortality and morbidity in non-cardiac and cardiac surgical procedures. Anemic surgical patients may require more blood transfusions, raising the risk of transfusion-related complications and increasing costs. For those reasons, optimizing patient readiness by correcting anemia prior to surgery is an important clinical goal. A simple new protocol has been proposed that helps correcting anemia using a single, high dose of recombinant human erythropoietin (HRE) administered only two days prior to surgery.

Minimal dose CT superior to chest X-ray for detection of recurrent lung cancer

Minneapolis, MN, May 6, 2013 – Lung cancer is associated with very high mortality, in part because it is hard to detect at early stages, but also because it can recur frequently after surgical removal. The question arises as to what is the best way to follow lung cancer patients after surgery in order to spot problems early enough, before symptoms become obvious, so that patients may still be eligible for new interventions.

Reversal of the black widow myth

The Black Widow spider gets its name from the popular belief that female spiders eat their male suitors after mating. However, a new study has shown that the tendency to consume a potential mate is also true of some types of male spider. The study by Lenka Sentenska and Stano Pekar from Masaryk University in the Czech Republic finds that male spiders of the Micaria sociabilis species are more likely to eat the females than be eaten. The paper, published in Springer's journal Behavioral Ecology and Sociobiology, outlines possible reasons for this behavior.

Activity of cancer inducing genes can be controlled by the cell's skeleton

Cancer is a complex disease, in which cells undergo a series of alterations, including changes in their architecture; an increase in their ability to divide, to survive and to invade new tissues or metastasis. A category of genes, called oncogenes, is critical during cancer progression, as they codify proteins whose activity favours the development of cancer. One of these molecules, Src, is implicated in a large number of human cancers. However, it is still not clear how healthy cells constrain its activity not to become tumorous.

Children living near toxic waste sites experience higher blood lead levels resulting in lower IQ

May 6, 2013 /Press Release/ –– Children living near toxic waste sites in lower and middle income countries such as India, Philippines and Indonesia may experience higher blood lead levels, resulting in a loss of IQ points and a higher incidence of mental retardation, according to a study presented today by Kevin Chatham-Stephens, MD, Pediatric Environmental Health Fellow at the Icahn School of Medicine at Mount Sinai, at the Pediatric Academic Societies (PAS) annual meeting on May 6 in Washington, DC.

Teen girls who exercise are less likely to be violent

WASHINGTON, DC – Regular exercise is touted as an antidote for many ills, including stress, depression and obesity. Physical activity also may help decrease violent behavior among adolescent girls, according to new research to be presented Monday, May 6, at the Pediatric Academic Societies (PAS) annual meeting in Washington, DC.

Researchers from Columbia University analyzed results of a 2008 survey completed by 1,312 students at four inner-city high schools in New York to determine if there was an association between regular exercise and violence-related behaviors.

High school athletes say concussions won't sideline them

WASHINGTON, DC – Many high school football players say it's OK to play with a concussion even though they know they are at risk of serious injury, according to a study to be presented Monday, May 6, at the Pediatric Academic Societies (PAS) annual meeting in Washington, DC.

The study of 120 high school football players in the Cincinnati area also found that one-quarter had suffered a concussion, and more than half acknowledged they would continue to play with symptoms of a concussion.

Research supports laws that require bicyclists to wear helmets

WASHINGTON, DC —Bicycle helmets save lives, and their use should be required by law. That's the conclusion of a study to be presented Monday, May 6, at the Pediatric Academic Societies (PAS) annual meeting in Washington, DC.

"This study highlights the importance of regulations in the promotion of safe exercise," said lead author William P. Meehan III, MD, FAAP, director of the Micheli Center for Sports Injury Prevention and the Sports Concussion Clinic at Boston Children's Hospital.

Many parents multi-task while driving kids

WASHINGTON, DC – Many parents are putting their precious cargo at risk while driving, according to survey results that will be presented May 5 and 6 at the Pediatric Academic Societies (PAS) annual meeting in Washington, DC.

Researchers from the University of Michigan surveyed more than 600 parents to find out what distractions they face while driving with their children, whether they use age-appropriate child restraints and if they had ever been in a motor vehicle accident.

Foster care a sound choice for some maltreated children

WASHINGTON, DC – Newspaper articles, TV shows and books are filled with horror stories of children placed in foster care. A new study bucks that trend by showing out-of-home placements can improve the emotional health of some youths who have been maltreated by a parent.

The study, led by Ann-Marie Conn, PhD, general pediatric academic fellow at University of Rochester Medical Center in New York, will be presented Monday, May 6, at the Pediatric Academic Societies (PAS) annual meeting in Washington, DC.

Nearly 20 percent of suicidal youths have guns in their home

WASHINGTON, DC – Nearly one in five children and teens found to be at risk for suicide report that there are guns in their homes, and 15 percent of those at risk for suicide with guns in the home know how to access both the guns and the bullets, according to a study to be presented Monday, May 6, at the Pediatric Academic Societies (PAS) annual meeting in Washington, DC.

National study of nanomaterial toxicity sets stage for policies to address health risks

For the first time, researchers from institutions around the country have conducted an identical series of toxicology tests evaluating lung-related health impacts associated with widely used engineered nanomaterials (ENMs). The study provides comparable health risk data from multiple labs, which should help regulators develop policies to protect workers and consumers who come into contact with ENMs.

Study raises concerns that teen athletes continue to play with concussion symptoms

Despite knowing the risk of serious injury from playing football with a concussion, half of high school football players would continue to play if they had a headache stemming from an injury sustained on the field.

In a new study, physicians from Cincinnati Children's Hospital Medical Center also report that approximately half of athletes wouldn't report concussion symptoms to a coach.

The study will be presented May 6 at the annual meeting of the Pediatric Academic Societies in Washington, DC.

Summer sees a spike in chemical injuries in kids

"Inquisitive children mistakenly identify hydrocarbons as a food or beverage and attempt to ingest the poison, which is the most common way children are exposed to the chemical," explained study co-author Lara McKenzie, PhD, MA, principal investigator in the Center for Injury Research and Policy at Nationwide Children's. "The changing seasons should remind parents to ensure proper storage of hydrocarbons in their original containers."