Body

Scientists aim to kill lung tumors

Using nanoclays to build better asphalt pavement

Long before freeways and parking lots, a naturally occurring asphalt first appeared on roads in about 600 B.C. You can still see patches of it in the ancient city of Babylon.

Under the onslaught of 21st century traffic, modern asphalt isn't likely to hold up for anywhere near 2,700 years. But at Michigan Technological University, Zhanping You is paving the way for brand-new asphalt blends to fight off cracks, rutting and potholes.

Scientists identify prostate cancer stem cells among low-PSA cells

HOUSTON – Prostate cancer cells that defy treatment and display heightened tumor-generating capacity can be identified by levels of prostate specific antigen (PSA) expressed in the tumor cells, a research team led by scientists at The University of Texas MD Anderson Cancer Center reports in the May 3 edition of Cell Stem Cell.

Expensive hospital readmissions linked to health-care-associated infections

CHICAGO (May 4, 2012) - New research finds a strong link between healthcare-associated infections (HAIs) and patient readmission after an initial hospital stay. The findings, published in the June 2012 issue of Infection Control and Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America (SHEA), suggest that reducing such infections could help reduce readmissions, considered to be a major driver of unnecessary healthcare spending and increased patient morbidity and mortality.

Hip implant for long-term use

Thanks to artificial hips, people with irreparable damage to the joint have been able to lead active, pain-free lives for the past 50 years. Still, some hip replacements do not function completely as intended, and metal-on-metal implants in particular, demand accurate positioning in surgery and implants positioned non optimally are often susceptible to premature failure notably in small female patients.

U of M researchers develop new muscular dystrophy treatment approach using human stem cells

MINNEAPOLIS/SAINT PAUL (May 4, 2012) – Researchers from the University of Minnesota's Lillehei Heart Institute have effectively treated muscular dystrophy in mice using human stem cells derived from a new process that – for the first time – makes the production of human muscle cells from stem cells efficient and effective.

Plant diversity is key to maintaining productive vegetation

Vegetation, such as a patch of prairie or a forest stand, is more productive in the long run when more plant species are present, results of a new study show.

The long-term study of plant biodiversity found that each species plays a role in maintaining a productive ecosystem, especially when a long time horizon is considered.

The research found that every additional species in a plot contributed to a gradual increase in both soil fertility and biomass production over a 14-year period.

Nutrient supply after algal bloom determines the succession of the bacterial population

Algal blooms can considerably interfere with summer holidays by the sea. In the coastal zone of temperate regions a spring algal bloom is not a sign of excessive nutrient input, but most of all a consequence of the more intense solar irradiation in spring. When algal blooms end, the algae die and their remnants constitute an important nutrient supply for the whole ecosystem.

MicroRNA controls malignancy and resistance of breast cancer cells

Many breast cancer patients are treated with a drug called tamoxifen. The substance blocks the effect of estrogen and thus suppresses the growth signals of this hormone in cancer cells. When resistance to the drug develops, tumor cells change their growth program: They change their behavior and shape, become more mobile and also adopt the ability to invade surrounding tissue. Scientists working with PD (Associate Professor) Dr. Stefan Wiemann of the German Cancer Research Center (DKFZ) have now also observed these changes in tamoxifen resistant breast cancer cells.

Protein signal is crucial for accurate control of insect size

HEIDELBERG, 4 May 2012 – Two independent groups of researchers have identified a hormone that is responsible for keeping the growth and development of insects on track. The results, which are reported in the journal Science, suggest that Dilp8 provides an important signal to slow body growth and delay insect development. This braking effect is an essential part of normal development since it allows sufficient time for tissues to form and the correct body size, proportions and symmetry to be achieved.

Low testosterone levels could raise diabetes risk for men

Low levels of testosterone in men could increase their risk of developing diabetes, a study suggests.

Scientists have found that low testosterone levels are linked to a resistance to insulin, the hormone that controls blood sugar levels.

The study is the first to directly show how low testosterone levels in fat tissue can be instrumental in the onset of Type 2 diabetes.

Testosterone is present throughout the body. Low testosterone levels are linked to obesity, a known risk factor for diabetes.

Different recipes for success in the world of plants

Better prognosis for breast cancer in Germany

How successful is the interdisciplinary treatment of breast cancer? Since 2003, the Breast Center at Heidelberg University Hospital has systematically tracked the course of breast cancer in more than 3,000 patients and, as the first center in Germany, has published these significant prospective results: Eighty-six percent of the patients survived the first five years after onset of treatment, with 80 % of them remaining disease-free during this period. The evaluation was published online in February 2012 in the journal The Breast.

UCSB researchers find that less is more, for female cowbirds

(Santa Barbara, Calif.) — More modest male displays attract the females when it comes to brown-headed cowbirds, contrary to sexual selection theory, according to UC Santa Barbara researchers Adrian O'Loghlen and Stephen Rothstein. Their findings are published May 2 in the open access journal PLoS ONE.

Comorbidities increase risk of mortality in COPD patients

Comorbidities are common among patients with chronic obstructive pulmonary disease (COPD), and a number of these comorbidities are independently associated with an increased mortality risk, according to a new study.