Body

New study published on fertility awareness among American university students

ORANGE, Calif. – A groundbreaking study lead by Chapman University professor Brennan Peterson, Ph.D. on fertility awareness of American college students will be published in the May 5th edition of Human Reproduction—a top-tier international journal in reproductive biology. It is the first such study on fertility awareness among American undergraduate university students. In the USA, the postponement of childbearing is reflective of contemporary social norms of delaying marriage, pursuing education and securing economic stability prior to having a baby.

Journals and pharma collaborate on new recommendations

ROCHESTER, Minn. -- The Medical Publishing Insights and Practices (MPIP) initiative and its co-sponsors recently collaborated with journal editors to characterize the persistent and perceived credibility gap in reporting industry-sponsored research and to identify potential approaches to resolve it. This unique round table, hosted by MPIP, reached consensus on Ten Recommendations for Closing the Credibility Gap in Reporting Industry-Sponsored Clinical Research as reported in the May issue of Mayo Clinic Proceedings.

Scarring cells revert to inactive state as liver heals

An international team of scientists, led by researchers at the University of California, San Diego School of Medicine, report that significant numbers of myofibroblasts – cells that produce the fibrous scarring in chronic liver injury – revert to an inactive phenotype as the liver heals. The discovery in mouse models could ultimately help lead to new human therapies for reversing fibrosis in the liver, and in other organs like the lungs and kidneys.

The work is published in the May 7, 2012 online Early Edition of the Proceedings of the National Academy of Sciences.

Diabetes drug could treat leading cause of blindness

University of Texas Medical Branch at Galveston researchers have discovered that a drug already prescribed to millions of people with diabetes could also have another important use: treating one of the world's leading causes of blindness.

Protein may represent a switch to turn off B cell lymphoma

Researchers studying the molecular signals that drive a specific type of lymphoma have discovered a key biological pathway leading to this type of cancer. Cancerous cells have been described as being "addicted" to certain oncogenes (cancer-causing genes), and the new research may lay the groundwork for breaking that addiction and effectively treating aggressive types of B cell lymphoma.

B cell lymphomas, which occur both in children and adults, are cancers that attack B cells in the immune system.

Screening for breast cancer without X-rays: Lasers and sound merge in promising diagnostic technique

WASHINGTON, May 7—X-ray mammography is an important diagnostic tool in the fight against breast cancer, but it has certain drawbacks that limit its effectiveness. For example, it can give in false positive and negative results; it also exposes women to low doses of ionizing radiation, which – while accepted as safe – still carry some risk.

Scientists discover new type of cell with a key role in treatment-resistant asthma

ANN ARBOR, Mich. — For most people with asthma, a couple of puffs from an inhaler filled with steroids makes breathing easy. But if their lungs become resistant to the calming effect of that medicine, they live in fear of severe asthma attacks that could send them to the hospital – or worse.

Now, new research from the University of Michigan Health System may help explain what's going on in the lungs of these steroid-resistant individuals. The findings could aid the development of new treatment options, and of better ways to identify people at risk of becoming steroid-resistant.

Oral zinc may lessen common cold symptoms but adverse effects are common

Oral zinc treatments may shorten the duration of symptoms of the common cold in adults, although adverse effects are common, according to a study published in CMAJ (Canadian Medical Association Journal).

PSA screening to detect prostate cancer can be beneficial to younger and at-risk men

Screening younger men and men at risk of prostate cancer can be beneficial in reducing metastatic cancer and deaths and should not be abandoned, states an article published in CMAJ (Canadian Medical Association Journal).

Biomarkers can reveal IBS

Irritable bowel syndrome (IBS) is hard to diagnose as well as treat, but researchers at the Sahlgrenska Academy, at the University of Gothenburg, Sweden, have discovered a way of confirming the disorder using stool samples.

Irritable bowel syndrome (IBS) causes chronic or recurring problems with pain and discomfort in the abdomen together with changes in bowel habits. The syndrome is common and is believed to be linked to dysfunction of the stomach and intestines, but our understanding of IBS is incomplete, making it difficult to diagnose and treat.

Keeping obesity rates level could save nearly $550 billion over 2 decades

WASHINGTON, D.C. – Researchers have forecast the cost savings and rise in obesity prevalence over the next two decades in a new public health study.

"Keeping obesity rates level could yield a savings of nearly $550 billion in medical expenditures over the next two decades," according to lead author Eric Finkelstein, Ph.D., associate research professor in the Duke Global Health Institute, as well as deputy director in the Health Services Research Program at Duke-NUS Graduate Medical School in Singapore.

Study shows school-based health centers boost vaccination rates

AURORA, Colo. (May 7, 2012) – New research from the University of Colorado School of Medicine shows that school-based health centers are highly effective in delivering comprehensive care, especially vaccines to adolescents.

The study, published today in the journal Pediatrics, highlights the value of a `captive audience' in a school setting where students can be easily reminded to get recommended vaccinations.

Study confirms early elevated HIV infection risk in some Step Study participants

SEATTLE – A long-term follow-up analysis of participants in the Step Study, an international HIV-vaccine trial, has confirmed that certain subgroups of male study participants were at higher risk of becoming infected after receiving the experimental vaccine compared to those who received a placebo. The vaccine used in the study did not contain the HIV virus, but it did contain HIV genes which were delivered to cells using a vector that employed a type of cold virus known as adenovirus serotype 5 (Ad5).

Biosignatures distinguish between tuberculosis and sarcoidosis

MSU plan would control deadly tsetse fly

EAST LANSING, Mich. — For the first time, scientists have created a satellite-guided plan to effectively control the tsetse fly – an African killer that spreads "sleeping sickness" disease among humans and animals and wipes out $4.5 billion in livestock every year.

Michigan State University researchers developed the plan using a decade's worth of NASA satellite images of Kenyan landscape and by monitoring tsetse movement. With unprecedented precision, the plan can tell where and when to direct eradication efforts.