Body

More than just bacteria: The importance of microbial diversity in gut health and disease

(March 10, 2014) The gut microbiota contains a vast number of microorganisms from all three domains of life, including bacteria, archaea and fungi, as well as viruses. These interact in a complex way to contribute towards both health and the development of disease — interactions that are only now being elucidated thanks to the application of advanced DNA sequencing technology in this field.

Farm salmon pose clear reproductive threat to wild gene pools

Farmed salmon show full reproductive potential to invade wild gene pools and should be sterilised - according to new research from the University of East Anglia (UEA).

Findings published today reveal that, while farmed salmon are genetically different to their wild counterparts, they are just as fertile. This is important information because millions of farmed salmon escape into the wild – posing threats to wild gene pools.

UEA research reveals 4 new man-made gases in the atmosphere

Scientists at the University of East Anglia have identified four new man-made gases in the atmosphere – all of which are contributing to the destruction of the ozone layer.

New research published today in the journal Nature Geoscience reveals that more than 74,000 tonnes of three new chlorofluorocarbons (CFCs) and one new hydrochlorofluorocarbon (HCFC) have been released into the atmosphere.

Mutations in leukemia gene linked to new childhood growth disorder

Mutations in a gene associated with leukaemia cause a newly described condition that affects growth and intellectual development in children, new research reports.

A study led by scientists at The Institute of Cancer Research, London, identified mutations in the DNA methyltransferase gene, DNMT3A, in 13 children.

All the children were taller than usual for their age, shared similar facial features and had intellectual disabilities. The mutations were not present in their parents, nor in 1,000 controls from the UK population.

In grasslands remade by humans, animals may protect biodiversity

COLLEGE PARK, Maryland – A comparative study of grasslands on six continents suggests there may be a way to counteract the human-made overdose of fertilizer that threatens to permanently alter the biodiversity of the world's native prairies.

New bioinformatics tool to visualize transcriptomes

ZENBU, a new, freely available bioinformatics tool developed at the RIKEN Center for Life Science Technology in Japan, enables researchers to quickly and easily integrate, visualize and compare large amounts of genomic information resulting from large-scale, next-generation sequencing experiments.

Spread of antibiotic resistance understood by unravelling bacterial secretion system

The system that allows the sharing of genetic material between bacteria – and therefore the spread of antibiotic resistance – has been uncovered by a team of scientists at Birkbeck, University of London and UCL.

U of M-led study finds herbivores can offset loss of plant biodiversity in grassland

Two wrongs may not make a right. But when it comes to grassland plant species diversity, it just might. Two impacts often controlled by humans — being fertilized and being eaten — can combine to the benefit of biodiversity, according to an innovative international study led by U of M researchers Elizabeth Borer and Eric Seabloom.

UNC researchers create new tool to unravel the mysteries of metastasis

If you could do this with all the circuit components, then this would allow you to learn how the circuitry is built.

"We are now doing this in live cells and seeing what happens," said Hahn, a member of the UNC Lineberger Comprehensive Cancer Center. "Kinases are the circuit components. And we can now activate just one kinase and study how it interacts with just one other molecule in real time."

Stem cell study opens door to undiscovered world of biology

DALLAS – March 9, 2014 – For the first time, researchers have shown that an essential biological process known as protein synthesis can be studied in adult stem cells – something scientists have long struggled to accomplish. The groundbreaking findings from the Children's Medical Center Research Institute at UT Southwestern (CRI) also demonstrate that the precise amount of protein produced by blood-forming stem cells is crucial to their function.

Deer proliferation disrupts a forest's natural growth

ITHACA, N.Y. – By literally looking below the surface and digging up the dirt, Cornell researchers have discovered that a burgeoning deer population forever alters the progression of a forest's natural future by creating environmental havoc in the soil and disrupting the soil's natural seed banks.

The study, "Deer Browsing Delays Succession by Altering Aboveground Vegetation and Belowground Seed Banks," was published online March 7 in PLOS ONE.

Research on 3D scaffolds sets new bar in lung regeneration

In end-stage lung disease, transplantation is sometimes the only viable therapeutic option, but organ availability is limited and rejection presents an additional challenge. Innovative research efforts in the field of tissue regeneration, including pioneering discoveries by University of Vermont (UVM) Professor of Medicine Daniel Weiss, M.D., Ph.D., and colleagues, holds promise for this population, which includes an estimated 12.7 million people with chronic obstructive pulmonary disorder (COPD), the third leading cause of death in the U.S.

The dark side of fair play

We often think of playing fair as an altru­istic behavior. We're sac­ri­ficing our own poten­tial gain to give others what they deserve. What could be more self­less than that? But new research from North­eastern Uni­ver­sity assis­tant pro­fessor of phi­los­ophy Rory Smead sug­gests another, darker origin behind the kindly act of fairness.

Notre Dame chemists discover new class of antibiotics

A team of University of Notre Dame researchers led by Mayland Chang and Shahriar Mobashery have discovered a new class of antibiotics to fight bacteria such as methicillin-resistant Staphylococcus aureus (MRSA) and other drug-resistant bacteria that threaten public health. Their research is published in the Journal of the American Chemical Society in an article titled "Discovery of a New Class of Non-beta-lactam Inhibitors of Penicillin-Binding Proteins with Gram-Positive Antibacterial Activity."

Anti-psychotic medications offer new hope in the battle against glioblastoma

Researchers at the University of California, San Diego School of Medicine have discovered that FDA-approved anti-psychotic drugs possess tumor-killing activity against the most aggressive form of primary brain cancer, glioblastoma. The finding was published in this week's online edition of Oncotarget.