Body

Treatment of Barrett's esophagus may lower risk of esophageal cancer

New guidelines issued by the American Gastroenterological Association (AGA) support the use of radiofrequency ablation (RFA) to remove precancerous cells in patients with Barrett's esophagus, a condition most commonly caused by chronic acid reflux, or GERD. Barrett's esophagus is the leading cause of esophageal cancer and affects an estimated two million Americans. While traditionally managed through watchful waiting, experts at Northwestern Medicine's Center for Esophageal Disease have been among the pioneers of ablation treatment and have long seen the benefits of early treatment.

'Epidemiological' study demonstrates climate change effects on forests

An 18-year study of 27,000 individual trees by National Science Foundation (NSF)-funded scientists finds that tree growth and fecundity--the ability to produce viable seeds--are more sensitive to climate change than previously thought.

The results, published tomorrow in the journal Global Change Biology, identify earlier spring warming as one of several factors that affect tree reproduction and growth.

Researchers mimic body's own healing potential to create personalised therapies for inflammation

Scientists at Barts and The London School of Medicine and Dentistry and Harvard Medical School, Boston have found a way of mimicking the body's natural mechanism of fighting inflammation. During inflammation cells release very small particles termed 'microparticles' that retain features of their parent cell. The scientists discovered that certain microparticles were beneficial to health, and that these microparticles contained anti-inflammatory lipids, which help terminate inflammation and return the body to its normal balance.

Mountain pine beetle marching east from Alberta

(Edmonton) A University of Alberta-led research team has determined that the mountain pine beetle has invaded jack pine forests in Alberta, opening up the possibility for an infestation that could stretch across the Prairies and keep moving east towards the Atlantic. . A group of U of A tree biologists and geneticists discovered that, as the mountain pine beetle spread eastward from central British Columbia, it successfully jumped species from its main host, the lodgepole pine, to the jack pine.

Young women with breast cancer have little fertility knowledge: Survey

Fertility is a priority for many young women with breast cancer, yet new research has found many have little knowledge about fertility issues, leading to confusion and conflict around planning for a family.

In a new study published in the Journal of Clinical Oncology, a team of University of New South Wales researchers has for the first time measured fertility-related knowledge and intentions in young women with breast cancer.

Soybean germplasm evaluations give US a head start against soybean rust pathogen

When soybean rust first appeared in the United States in late 2004, many producers feared devastating yield losses similar to losses experienced in other parts of the world. In response to this threat, researchers have been evaluating USDA soybean germplasm accessions for resistance to this fungus, and a recent report in Crop Science identifies some of these resistant sources.

Investigational direct-acting antiviral BMS-790052 plus PEG-interferon alfa and ribavirin achieved up to 92 percent sustained vi

(PRINCETON, N.J., March 31, 2011) – Bristol-Myers Squibb Company (NYSE: BMY)today announced results from a Phase II clinical trial in which treatment with the investigationaldirect-acting antiviral (DAA) BMS-790052, an NS5A replication complex inhibitor, incombination with PEG-Interferon alfa and ribavirin (RBV), achieved sustained virologicresponse 12 weeks post-treatment (SVR12) in up to 92% of treatment-naïve patients chronicallyinfected with hepatitis C (HCV) genotype 1 (10 mg dose arm, n=12).

2 sets of genes predict response to lung cancer drug

ORLANDO - Two sets of gene expression profiles predict response to a common lung cancer drug for patients that have no guiding indicators for their treatment now, scientists from The University of Texas MD Anderson Cancer Center report at the AACR 102nd Annual Meeting.

Investigational compound PEG-interferon lambda achieved higher response rates with fewer flu-like and musculoskeletal symptoms a

(PRINCETON, N.J., April 2, 2011) – Bristol-Myers Squibb Company (NYSE: BMY) today announced results from the Phase IIb EMERGE clinical trial, in which treatment with the investigational compound PEG-Interferon lambda and ribavirin achieved higher rates of rapid virologic response (RVR) in genotypes 1, 2, 3, and 4, and complete early virologic response (cEVR) in genotypes 1 and 4 than the standard regimen of PEG-Interferon alfa and ribavirin in treatment-naïve patients chronically infected with hepatitis C (HCV).

Climate change and evolution of Cross River gorillas

Two species of gorillas live in central equatorial Africa. Divergence between the Western gorillas (Gorilla gorilla) and Eastern gorillas (Gorilla beringei) began between 0.9 and 1.6 million years ago and now the two species live several hundred kilometres apart.

Are ICDs up to par with patients living longer?

Most patients with ischemic cardiomyopathy (ICM) and dilated cardiomyopathy (DCM) who have an implantable cardioverter-defibrillator (ICD) now live more than seven years and those ICD patients with hereditary heart disease can live for decades, based on a scientific paper that will be presented at the American College of Cardiology (ACC) Scientific Sessions in New Orleans, April 1-3.

Chest pain med is effective for refractory angina, but adherence problematic

Ranolazine (Ranexa, Gilead) is an effective anti-anginal therapy in patients with refractory angina; however, at one year only 59 percent of patients remained on the drug, according to a scientific poster that will be presented at the American College of Cardiology (ACC) Scientific Sessions in New Orleans, April 1-3.

Protocol-driven heart attack care proves effective and contagious

The implementation of acute heart attack or ST-elevation myocardial infarction (STEMI) guidelines, protocols and standing orders in Minnesota community hospitals without cardiac catheterization labs has dramatically improved since 2003, according to a scientific poster that will be presented at the American College of Cardiology (ACC) Scientific Sessions in New Orleans, April 1-3.

New information provides sustainable options for greenhouse operations

FAYETTEVILLE, AR—Containers made from plastics are used in most traditional greenhouse operations. While plastic containers are practical, strong, and can be formed to any size, shape, or color, the extensive use of these petroleum-based containers creates significant waste disposal problems for the greenhouse industry and consumers. One example: a 2008 report found that a typical greenhouse operation in California discards over 3560 pounds of plastic trays, flats, and containers annually.

Clumsy kids who don't 'grow out of it'

Attention Deficit Hyperactivity Disorder, or ADHD, is widely recognized by the medical community, and there are a number of therapies in place. But as many as six percent of all children suffer from the less familiar Developmental Coordination Disorder (DCD). Demonstrating a lack of refined motor skills, children with DCD tend to have a more difficult time playing sports and staying organized at school. They appear to be uncoordinated — and many parents think they'll grow out of it. But research shows that may not be true.