Body

Diesel-engine exhaust filter reduces harmful particles by 98 percent

A commercially available particle trap can filter microscopic pollutants in diesel-engine exhaust and prevent about 98 percent of them from reaching the air, according to research reported in Circulation: Journal of the American Heart Association.

Inhaling exhaust particles increases the risk of dying from heart and lung diseases. Air pollution, including diesel exhaust as a major contributor, causes 800,000 premature deaths annually in the world, according to the World Health Organization.

Distribution of cancers in the HIV/AIDS population is shifting

As treatments for HIV/AIDS improve and patients are living longer, the distribution of cancers in this population has undergone a dramatic shift in the United States. While cases of the types of cancer that have been associated with AIDS progression have decreased, cases of other types of cancer are on the rise. These results, reported by scientists from the National Cancer Institute (NCI), part of the National Institutes of Health, and the Centers for Disease Control and Prevention, were published online April 11, 2011, in the Journal of the National Cancer Institute.

Long-term use of antibiotic to treat acne not associated with increased bacterial resistance

The prolonged use of tetracycline antibiotics commonly used to treat acne was associated with a reduced prevalence of StaphylococcuS. aureus bacteria and was not associated with increased resistance to the tetracycline antibiotics, according to a report posted online today that will appear in the August print issue of Archives of Dermatology, one of the JAMA/Archives journals.

Cancer burden shifts for people with HIV/AIDS

The number of cancers and the types of cancers among people living with AIDS in the U.S. have changed dramatically during the 15-year period from 1991-2005, according to an article published online April 11th in the Journal of the National Cancer Institute.

High levels of vitamin D appear to lower risk of age-related macular degeneration in young women

High levels of vitamin D in the bloodstream appear to be associated with a decreased risk of developing early age-related macular degeneration among women younger than 75 years, according to a report in the April issue of Archives of Ophthalmology, one of the JAMA/Archives journals.

Study finds physicians recommend different treatments for patients than they choose for themselves

The act of making a recommendation appears to change the way physicians think regarding medical choices, and they often make different choices for themselves than what they recommend to patients, according to a survey study published in the April 11 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

Vitamin D levels associated with age-related macular degeneration

BUFFALO, N.Y. -- Women under the age of 75 with high vitamin D status were less likely to have early age-related macular degeneration (AMD), the leading cause of irreversible vision loss in adults, a University at Buffalo study has shown. The disease affects approximately 9 percent of Americans aged 40 and older.

The paper is published in the April issue of "Archives of Ophthalmology," one of the JAMA/Archives journals.

Estrogen treatment with no side-effects in sight

Oestrogen treatment for osteoporosis has often been associated with serious side-effects. Researchers at the Sahlgrenska Academy, University of Gothenburg, Sweden, have now, in mice, found a way of utilising the positive effects of oestrogen in mice so that only the skeleton is acted on, current research at the Academy shows.

The study is presented in the respected journal PNAS (Proceedings of the National Academy of Sciences).

New genetic tool helps researchers to analyze cells' most important functions

Although it has been many years since the human genome was first mapped, there are still many genes whose function we do not understand. Researchers from the University of Gothenburg, Sweden, and the University of Toronto, Canada, have teamed up to produce and characterize a collection of nearly 800 strains of yeast cells that make it possible to study even the most complicated of genes.

Antibiotic resistance spreads rapidly between bacteria

The part of bacterial DNA that often carries antibiotic resistance is a master at moving between different types of bacteria and adapting to widely differing bacterial species, shows a study made by a research team at the University of Gothenburg in cooperation with Chalmers University of Technology. The results are published in an article in the scientific journal Nature Communications.

New drug shows potential for treatment-resistant leukemia

BOSTON (April 11) --A study from Tufts Medical Center researchers published today finds that a novel drug shows promise for treating leukemia patients who have few other options because their disease has developed resistance to standard treatment.

Appearing in the journal Cancer Cell, the study is the first published report showing that the drug, DCC-2036, fights chronic myeloid leukemia (CML) in a mouse model of the disease and is effective against human leukemia cells.

Emory Healthcare's unique training shows signific knowledge of quality principles

ATLANTA – The effectiveness of a unique two-pronged educational program has shown significant improvements in knowledge of quality principles by leaders as well as the successful design and launch of QI (quality improvement) projects by frontline staff, according to results outlined in an article in the April 2011 issue of The Joint Commission Journal on Quality and Patient Safety (http://www.jcrinc.com/The-Joint-Commission-Journal-on-Quality-and-Patient-Safety/Current-Is

Haiti cholera epidemic could have been blunted with use of mobile stockpile of oral vaccine

SEATTLE – Had a large stockpile of oral cholera vaccine been available and deployed to inoculate the majority of Haitians most at risk after the outbreak following last year's earthquake, the illness and death from the cholera epidemic could have been reduced by about half, according to new research.

The findings, by Ira Longini, Ph.D., and colleagues in the Vaccine and Infectious Disease Division of Fred Hutchinson Cancer Research Center, are published in the April 11, 2011 early edition of the Proceedings of the National Academy of Sciences.

Tissue engineers use new system to measure biomaterials, structures

PROVIDENCE, R.I. [Brown University] — Tissue engineering makes biologists builders, but compared to their civil engineering counterparts, they don't know much about the properties of the materials and structures they use, namely living cells. To improve that knowledge, Brown University researchers have developed a simple and reliable system for measuring the power that cells employ to assemble into three-dimensional tissue. The research appears online the week of April 11 in Proceedings of the National Academy of Sciences.

Scientists flex their muscles to solve an old problem

In a famous experiment first performed more than 220 years ago, Italian physician Luigi Galvani discovered that the muscles of a frog's leg twitch when an electric voltage is applied. An international group of scientists from Italy, the UK and France has now brought this textbook classic into the era of nanoscience. They used a powerful new synchrotron X-ray technique to observe for the first time at the molecular scale how muscle proteins change form and structure inside an intact and contracting muscle cell.