Body

A molecule that lies dormant until it encounters a cancer cell, then suddenly activates and rouses the body's immune system to fight cancer cells directly, marks the latest step in scientists' efforts to tap the body's own resources to fight the disease.

The developers of the technology at the University of Rochester Medical Center dub it the "Pacman strategy" because it hinges upon molecular machines produced in abundance by tumors to chew through and gobble up particular chains of molecules.

BLOOMINGTON, Ind. -- The discovery of two genes that encode copper- and sulfur-binding repressors in the hospital terror Staphylococcus aureus means two new potential avenues for controlling the increasingly drug-resistant bacterium, scientists say in the April 15, 2011 issue of the Journal of Biological Chemistry.

"We need to come up with new targets for antibacterial agents," said Indiana University Bloomington biochemist David Giedroc, who led the project. "Staph is becoming more and more multi-drug resistant, and both of the systems we discovered are promising."

New York, NY, April 11, 2011 – How do we assess the current and future quality of life (QoL) for infants and children with life-threatening conditions? In the April issue of Current Problems in Pediatric and Adolescent Health Care, "The Quality of Life of Young Children and Infants with Chronic Medical Problems," presents a collection of essays in which physicians, medical ethicists, parents, and caregivers address one of the most contentious topics in pediatric and clinical ethics today, the assessment of QoL).

Mothers' exposure during pregnancy to pollutants created by the incomplete combustion of fossil fuels and other organic material may lead to behavioral problems in their children, according to a new study. Researchers found that within a sample of 215 children monitored from birth, those children with high levels of a pollution exposure marker in their cord blood had more symptoms of attention problems and anxiety/depression at ages 5 and 7 than did children with lower exposure.

Osteoporosis constitutes a major public health problem through its association with age-related fractures, most notably those of the hip. As life expectancy rises around the world, along with the number of elderly people in every geographic region, the incidence of hip fractures is estimated to reach 6.3 million in 2050 - assuming a constant age-specific rate of fracture in men and women.

Animal and bird species found only on a single island should still be common within that island.

This is the finding of a new model developed by researchers from the University of Leeds and Imperial College London. The model could apply both to actual islands and isolated areas of habitat on the mainland that are home to unique species, such as the table top mountains of South America.

Despite current prohibitions on the words 'light' and 'mild', smokers in Western countries continue falsely to believe that some cigarette brands may be less harmful than others. In fact, all conventional brands of cigarette present the same level of risk to smokers, including 'mild' and 'low-tar' brands.

A new study conducted by researchers in the Center for Injury Research and Policy of The Research Institute at Nationwide Children's Hospital found that an estimated 5.25 million football-related injuries among children and adolescents between 6 and 17 years of age were treated in U.S. emergency departments between 1990 and 2007. The annual number of football-related injuries increased 27 percent during the 18-year study period, jumping from 274,094 in 1990 to 346,772 in 2007.

Nasal vaccines that effectively protect against flu, pneumonia and even bioterrorism agents such as Yersinia pestis that causes the plague, could soon be a possibility, according to research presented at the Society for General Microbiology's Spring Conference in Harrogate. Professor Dennis Metzger describes how including a natural immune chemical with standard vaccines can boost their protective effect when delivered through the nose.

Bacteria that grow in the antennae of wasps help ward off fungal threats by secreting a 'cocktail' of antibiotics explains a scientist at the Society for General Microbiology's Spring Conference in Harrogate.

Dr Martin Kaltenpoth describes how this is the first known example of non-human animals using a combination prophylaxis strategy similar to the one used in human medicine. This discovery could help us find novel antimicrobials for human use and lead to more effective strategies for using them.

CAMBRIDGE, Mass (April 11, 2011)—In a research collaboration blind to affairs of politics, ethnicity, and religion, an international team led by Israeli scientists has identified the genetic cause of a neurological disorder afflicting members of a Palestinian family.

Taking a statin before having major elective surgery reduces potentially serious kidney complications, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology (JASN).

Each year, more than 230 million major elective surgeries are performed around the world. Unfortunately, many patients who undergo major operations develop kidney injury soon after surgery, often due to decreased blood flow to the kidneys and/or the effects of inflammation.

PORTLAND, Ore. — An Oregon Health & Science University researcher has co-authored an international study that revealed a drug approved to prevent rejection in organ transplant patients helped treat a rare lung disease in women.

The life-threatening disease has no cure and, until now, no known treatment.

The clinical trial of the drug -- called sirolimus -- was the first randomized, controlled study designed to develop a therapy for the lung disease, lymphangioleiomyomatosis, or LAM.

HONOLULU – The American Academy of Neurology has issued a new guideline on the most effective treatments for diabetic nerve pain, the burning or tingling pain in the hands and feet that affects millions of people with diabetes. The guideline is published in the April 11, 2011, online issue of Neurology®, the medical journal of the American Academy of Neurology, and will be presented April 11, 2011, at the American Academy of Neurology's Annual Meeting in Honolulu.

Measuring the wrist bone may be a new way to identify which overweight children and adolescents face an increased risk of developing cardiovascular disease, according to research in Circulation: Journal of the American Heart Association.